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Biology and Biochemistry

D-Index
61
Citations
10545
World Ranking
11575
National Ranking
225

Research.com Recognitions

  • 1993 - Member of Academia Europaea
  • 1991 - Fellow, The World Academy of Sciences

Overview

Federico Mayor is affiliated with the Spanish National Research Council in Spain. Their research spans multiple areas within medicine and biochemistry, genetics, and molecular biology, focusing particularly on molecular biology, oncology, and cell biology. Their work also touches on epidemiology and surgery.

The scientist's research agenda covers a range of specialized topics, including:

  • Receptor mechanisms and signaling
  • Chemokine receptors and signaling
  • Microtubule and mitosis dynamics
  • Immunotherapy and immune responses
  • Pancreatic function and diabetes
  • Metabolism, diabetes, and cancer
  • Cardiac electrophysiology and arrhythmias

Federico Mayor has contributed papers to various scientific venues, with repeated publications in the journal Cells and preprints in bioRxiv (Cold Spring Harbor Laboratory). Other publication outlets include The Annual Review of Pharmacology and Toxicology, International Journal of Molecular Sciences, and Cell Death Discovery.

Recent notable publications by Federico Mayor include:

  • The CXCL12/CXCR4/ACKR3 Axis in the Tumor Microenvironment: Signaling, Crosstalk, and Therapeutic Targeting (2020) in The Annual Review of Pharmacology and Toxicology
  • Gαq activation modulates autophagy by promoting mTORC1 signaling (2021) in Nature Communications
  • GRK2-Dependent HuR Phosphorylation Regulates HIF1α Activation under Hypoxia or Adrenergic Stress (2020) in Cancers
  • Crosstalk between CXCR4/ACKR3 and EGFR Signaling in Breast Cancer Cells (2022) in International Journal of Molecular Sciences
  • GRK2 regulates GLP-1R-mediated early phase insulin secretion in vivo (2021) in BMC Biology

Frequent collaborators in Federico Mayor's research include:

  • Petronila Penela
  • Cristina Murga
  • Alba C. Arcones
  • Verónica Rivas
  • Catalina Ribas

Federico Mayor has been recognized with memberships and fellowships, including:

  • Member of Academia Europaea (1993)
  • Fellow, The World Academy of Sciences (1991)

Best Publications

  • The G protein-coupled receptor kinase (GRK) interactome: Role of GRKs in GPCR regulation and signaling

    Catalina Ribas;Petronila Penela;Cristina Murga;Alicia Salcedo

  • Mechanisms of regulation of the expression and function of G protein-coupled receptor kinases.

    Petronila Penela;Catalina Ribas;Federico Mayor

  • Purification and characterization of the beta-adrenergic receptor kinase.

    J L Benovic;F Mayor;C Staniszewski;R J Lefkowitz

  • The chemokine monocyte chemotactic protein 1 triggers Janus kinase 2 activation and tyrosine phosphorylation of the CCR2B receptor.

    M. Mellado;J. M. Rodríguez-Frade;A. Aragay;G. del Real

  • Light-dependent phosphorylation of rhodopsin by β -adrenergic receptor kinase

    Jeffrey L. Benovic;Federico Mayor;Robert L. Somers;Marc G. Caron

  • The complex G protein-coupled receptor kinase 2 (GRK2) interactome unveils new physiopathological targets

    Petronila Penela;Cristina Murga;Catalina Ribas;Vanesa Lafarga

  • Mechanisms of regulation of G protein-coupled receptor kinases (GRKs) and cardiovascular disease

    Petronila Penela;Cristina Murga;Catalina Ribas;Antonio S. Tutor

  • Monocyte chemoattractant protein-1-induced CCR2B receptor desensitization mediated by the G protein-coupled receptor kinase 2

    A. M. Aragay;M. Mellado;J. M. R. Frade;A. M. Martin

  • Agonist-dependent phosphorylation of the alpha 2-adrenergic receptor by the beta-adrenergic receptor kinase.

    J. L. Benovic;J. W. Regan;H. Matsui;F. Mayor

  • β-arrestin- and c-Src-dependent degradation of G-protein-coupled receptor kinase 2

    Petronila Penela;Ana Elorza;Susana Sarnago;Federico Mayor

  • Phosphorylation of p38 by GRK2 at the Docking Groove Unveils a Novel Mechanism for Inactivating p38MAPK

    Sandra Peregrin;Maria Jurado-Pueyo;Pedro M. Campos;Victoria Sanz-Moreno

  • Mdm2 is involved in the ubiquitination and degradation of G-protein-coupled receptor kinase 2.

    Alicia Salcedo;Federico Mayor;Petronila Penela

  • Degradation of the G Protein-coupled Receptor Kinase 2 by the Proteasome Pathway *

    Petronila Penela;Ana Ruiz-Gómez;José G. Castaño;Federico Mayor

  • Agonist-dependent Phosphorylation of the G Protein-coupled Receptor Kinase 2 (GRK2) by Src Tyrosine Kinase

    Susana Sarnago;Ana Elorza;Federico Mayor

  • Modulation of inhibitory glycine receptors by phosphorylation by protein kinase C and cAMP-dependent protein kinase.

    M L Vaello;A Ruiz-Gómez;J Lerma;F Mayor

  • beta-Adrenergic receptor kinase. Activity of partial agonists for stimulation of adenylate cyclase correlates with ability to promote receptor phosphorylation.

    J L Benovic;C Staniszewski;F Mayor;M G Caron

  • The Adenosine A2A Receptor Interacts with the Actin-binding Protein α-Actinin *

    Javier Burgueño;Derek J. Blake;Matthew A. Benson;Caroline L. Tinsley

  • Somatostatin induces translocation of the beta-adrenergic receptor kinase and desensitizes somatostatin receptors in S49 lymphoma cells.

    F Mayor;J L Benovic;M G Caron;R J Lefkowitz

  • Reduced GRK2 level in T cells potentiates chemotaxis and signaling in response to CCL4.

    Anne Vroon;Cobi Jacoba Johanna Heijnen;Maria Stella Lombardi;Pieter M. Cobelens

  • Signaling pathways for monocyte chemoattractant protein 1-mediated extracellular signal-regulated kinase activation.

    M. Carmen Jiménez-Sainz;Beate Fast;Federico Mayor;Anna M. Aragay

Frequent Co-Authors

Cobi Jacoba Johanna Heijnen
Cobi Jacoba Johanna Heijnen The University of Texas MD Anderson Cancer Center
Annemieke Kavelaars
Annemieke Kavelaars The University of Texas MD Anderson Cancer Center
Jesús Vázquez
Jesús Vázquez Spanish National Centre for Cardiovascular Research
Robert J. Lefkowitz
Robert J. Lefkowitz Duke University
David Garcia-Dorado
David Garcia-Dorado Autonomous University of Barcelona
Marc G. Caron
Marc G. Caron Duke University
Jeffrey L. Benovic
Jeffrey L. Benovic Thomas Jefferson University
Francisco Sánchez-Madrid
Francisco Sánchez-Madrid Autonomous University of Madrid
José M. Cuezva
José M. Cuezva Autonomous University of Madrid
Martine J. Smit
Martine J. Smit Vrije Universiteit Amsterdam

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