World's Best Scientists 2026 revealed!
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Best Scientists
2025
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Biology and Biochemistry
USA
2023

D-Index & Metrics

Best Scientists

D-Index
209
Citations
143608
World Ranking
211
National Ranking
137

Biology and Biochemistry

D-Index
208
Citations
144500
World Ranking
28
National Ranking
23

Research.com Recognitions

  • 2025 - Research.com Best Scientists Award
  • 2023 - Research.com Biology and Biochemistry in United States Leader Award
  • 2015 - Fellow of the American Academy of Arts and Sciences
  • 2013 - Fellow of the American Association for the Advancement of Science (AAAS)

Overview

Marc G. Caron was affiliated with Duke University in the United States. Their research spanned multiple scientific fields, primarily in biochemistry, genetics, and molecular biology, with additional contributions to neuroscience and medicine. Their scientific work included key subfields such as molecular biology, cellular and molecular neuroscience, oncology, radiology, nuclear medicine and imaging, and physiology.

The main topics explored in their research focused on receptor mechanisms and signaling, neuropeptides and animal physiology, neurotransmitter receptor influence on behavior, neuroscience and neuropharmacology research, pharmacological receptor mechanisms and effects, monoclonal and polyclonal antibodies research, and chemokine receptors and signaling.

The scientist contributed to a number of research articles published in notable venues. Frequent publication venues included UNC Libraries, bioRxiv (Cold Spring Harbor Laboratory), Cell, IUPHAR/BPS Guide to Pharmacology CITE, and Trends in Pharmacological Sciences.

Among the recent scientific papers authored as part of their research network were:

  • Biased Allosteric Modulators: New Frontiers in GPCR Drug Discovery, 2021, Trends in Pharmacological Sciences
  • β-Arrestin-Biased Allosteric Modulator of NTSR1 Selectively Attenuates Addictive Behaviors, 2020, Cell
  • Noncanonical scaffolding of G αi and β-arrestin by G protein-coupled receptors, 2021, Science
  • Neurotensin Receptor Allosterism Revealed in Complex with a Biased Allosteric Modulator, 2023, Biochemistry
  • Ghrelin receptor signaling in health and disease: a biased view, 2022, Trends in Endocrinology and Metabolism

The scientist collaborated frequently with a range of co-authors, including Lawrence S Barak, William C. Wetsel, Lauren M. Slosky, Thomas F. Pack, and Raul R. Gainetdinov. This collaborative network supported the production of multiple publications and research findings.

Marc G. Caron was recognized with several honors during their career, including election as a Fellow of the American Academy of Arts and Sciences in 2015 and as a Fellow of the American Association for the Advancement of Science (AAAS) in 2013.

Best Publications

  • Dopamine Receptors: From Structure to Function

    Cristina Missale;S. Russel Nash;Susan W. Robinson;Mohamed Jaber

  • Hyperlocomotion and indifference to cocaine and amphetamine in mice lacking the dopamine transporter

    B Giros;M Jaber;S R Jones;R M Wightman

  • Model systems for the study of seven-transmembrane-segment receptors.

    Henrik G. Dohlman;Jeremy Thorner;Marc G. Caron;Robert J. Lefkowitz

  • Beta-arrestin-dependent formation of beta2 adrenergic receptor-Src protein kinase complexes.

    L. M. Luttrell;S. S. G. Ferguson;Y. Daaka;W. E. Miller

  • Turning off the signal: desensitization of beta-adrenergic receptor function.

    William P. Hausdorff;Marc G. Caron;Robert J. Lefkowitz

  • Cloning of the gene and cDNA for mammalian β -adrenergic receptor and homology with rhodopsin

    Richard A. F. Dixon;Brian K. Kobilka;David J. Strader;Jeffrey L. Benovic

  • Beta-arrestin: a protein that regulates beta-adrenergic receptor function

    Martin J. Lohse;Jeffrey L. Benovic;Juan Codina;Marc G. Caron

  • Mice with Reduced NMDA Receptor Expression Display Behaviors Related to Schizophrenia

    Amy R Mohn;Raul R Gainetdinov;Marc G Caron;Beverly H Koller

  • Plasma membrane monoamine transporters: structure, regulation and function

    Gonzalo E. Torres;Raul R. Gainetdinov;Marc G. Caron

  • An Akt/β-Arrestin 2/PP2A Signaling Complex Mediates Dopaminergic Neurotransmission and Behavior

    Jean-Martin Beaulieu;Tatyana D. Sotnikova;Sébastien Marion;Robert J. Lefkowitz

  • Role of β-Arrestin in Mediating Agonist-Promoted G Protein-Coupled Receptor Internalization

    Stephen S. G. Ferguson;William E. Downey;Anne-Marie Colapietro;Larry S. Barak

  • Enhanced Morphine Analgesia in Mice Lacking β-Arrestin 2

    Laura M. Bohn;Robert J. Lefkowitz;Raul R. Gainetdinov;Karsten Peppel

  • Mu-opioid receptor desensitization by beta-arrestin-2 determines morphine tolerance but not dependence.

    Laura M. Bohn;Raul R. Gainetdinov;Fang-Tsyr Lin;Robert J. Lefkowitz

  • Role of serotonin in the paradoxical calming effect of psychostimulants on hyperactivity.

    Raul R. Gainetdinov;William C. Wetsel;Sara R. Jones;Edward D. Levin

  • Chimeric alpha 2-,beta 2-adrenergic receptors: delineation of domains involved in effector coupling and ligand binding specificity

    Brian K. Kobilka;Tong Sun Kobilka;Kiefer Daniel;John W. Regan

  • Recent Advances in the Molecular Biology of Dopamine Receptors

    Jay A. Gingrich;Marc G. Caron

  • Differential Affinities of Visual Arrestin, βArrestin1, and βArrestin2 for G Protein-coupled Receptors Delineate Two Major Classes of Receptors

    Robert H. Oakley;Stéphane A. Laporte;Jason A. Holt;Marc G. Caron

  • DESENSITIZATION OF G PROTEIN–COUPLED RECEPTORS AND NEURONAL FUNCTIONS

    Raul R. Gainetdinov;Richard T. Premont;Laura M. Bohn;Robert J. Lefkowitz

  • Cloning, sequencing, and expression of the gene coding for the human platelet alpha 2-adrenergic receptor

    B. K. Kobilka;H. Matsui;T. S. Kobilka;T. L. Yang-Feng

  • Cloning and expression of a functional serotonin transporter from rat brain.

    Randy D. Blakely;Haley E. Berson;Robert T. Fremeau;Marc G. Caron

Frequent Co-Authors

Robert J. Lefkowitz
Robert J. Lefkowitz Duke University
Raul R. Gainetdinov
Raul R. Gainetdinov Saint Petersburg State University
Larry S. Barak
Larry S. Barak Duke University
Tatyana D. Sotnikova
Tatyana D. Sotnikova Italian Institute of Technology
Bruno Giros
Bruno Giros McGill University
Jean-Martin Beaulieu
Jean-Martin Beaulieu University of Toronto
Stephen S. G. Ferguson
Stephen S. G. Ferguson University of Ottawa
William C. Wetsel
William C. Wetsel Duke University
Jeffrey L. Benovic
Jeffrey L. Benovic Thomas Jefferson University
Sara R. Jones
Sara R. Jones Wake Forest University

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