D-Index & Metrics Best Publications

D-Index & Metrics D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines.

Discipline name D-index D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines. Citations Publications World Ranking National Ranking
Biology and Biochemistry D-index 73 Citations 22,083 134 World Ranking 2581 National Ranking 78

Overview

What is he best known for?

The fields of study he is best known for:

  • G protein-coupled receptor
  • Signal transduction
  • Cell membrane

His scientific interests lie mostly in Cell biology, G protein-coupled receptor, G protein-coupled receptor kinase, Arrestin and Signal transduction. Stephen S. G. Ferguson interconnects Endocytic cycle, Endocytosis and Internalization in the investigation of issues within Cell biology. His G protein-coupled receptor study incorporates themes from Heterotrimeric G protein and Enzyme-linked receptor.

His research investigates the connection between Heterotrimeric G protein and topics such as Rhodopsin-like receptors that intersect with issues in Small G Protein, GTP-binding protein regulators, Transport protein and PDZ domain. His work in G protein-coupled receptor kinase addresses issues such as Mitogen-activated protein kinase kinase, which are connected to fields such as MAP kinase kinase kinase. His Signal transduction research includes elements of Agonist, Receptor, Opioid peptide and Pharmacology.

His most cited work include:

  • Evolving Concepts in G Protein-Coupled Receptor Endocytosis: The Role in Receptor Desensitization and Signaling (1630 citations)
  • Beta-arrestin-dependent formation of beta2 adrenergic receptor-Src protein kinase complexes. (1289 citations)
  • Role of β-Arrestin in Mediating Agonist-Promoted G Protein-Coupled Receptor Internalization (847 citations)

What are the main themes of his work throughout his whole career to date?

Stephen S. G. Ferguson focuses on Cell biology, G protein-coupled receptor, Receptor, Biochemistry and Signal transduction. His Cell biology research is multidisciplinary, incorporating perspectives in Internalization, Endocytosis and Metabotropic glutamate receptor. His G protein-coupled receptor study combines topics in areas such as Heterotrimeric G protein, G protein and Rhodopsin-like receptors.

In his research, Agonist is intimately related to Pharmacology, which falls under the overarching field of Receptor. In the subject of general Signal transduction, his work in Cell signaling is often linked to Green fluorescent protein, thereby combining diverse domains of study. Stephen S. G. Ferguson has included themes like 5-HT5A receptor, Enzyme-linked receptor and Beta adrenergic receptor kinase in his G protein-coupled receptor kinase study.

He most often published in these fields:

  • Cell biology (92.47%)
  • G protein-coupled receptor (42.47%)
  • Receptor (32.88%)

What were the highlights of his more recent work (between 2012-2021)?

  • Cell biology (92.47%)
  • G protein-coupled receptor (42.47%)
  • Metabotropic glutamate receptor 5 (13.01%)

In recent papers he was focusing on the following fields of study:

His primary areas of study are Cell biology, G protein-coupled receptor, Metabotropic glutamate receptor 5, Receptor and Endocytosis. His research is interdisciplinary, bridging the disciplines of HEK 293 cells and Cell biology. His biological study spans a wide range of topics, including Heterotrimeric G protein, Cell type and GTPase-activating protein.

His Metabotropic glutamate receptor 5 research incorporates elements of Metabotropic glutamate receptor 4, Neuroscience, Metabotropic glutamate receptor 7 and Metabotropic glutamate receptor 3. As a member of one scientific family, Stephen S. G. Ferguson mostly works in the field of Receptor, focusing on Endocrinology and, on occasion, G protein-coupled receptor kinase, Sensitization and Excitatory postsynaptic potential. His research investigates the link between Endocytosis and topics such as Intracellular that cross with problems in Arrestin, Transport protein, Desensitization, Rab and GTPase.

Between 2012 and 2021, his most popular works were:

  • Metabotropic glutamate receptor 5 knockout reduces cognitive impairment and pathogenesis in a mouse model of Alzheimer's disease (79 citations)
  • PDZ Protein Regulation of G Protein-Coupled Receptor Trafficking and Signaling Pathways. (70 citations)
  • A Dopamine D2 Receptor-DISC1 Protein Complex may Contribute to Antipsychotic-Like Effects (65 citations)

In his most recent research, the most cited papers focused on:

  • Signal transduction
  • G protein-coupled receptor
  • Cell membrane

Stephen S. G. Ferguson spends much of his time researching Cell biology, Receptor, G protein-coupled receptor, Metabotropic glutamate receptor 5 and Endocytosis. Stephen S. G. Ferguson is interested in Phosphorylation, which is a field of Cell biology. His studies deal with areas such as Endocrinology and GSK-3 as well as Receptor.

His study on G protein-coupled receptor is covered under Biochemistry. As a part of the same scientific family, Stephen S. G. Ferguson mostly works in the field of Metabotropic glutamate receptor 5, focusing on Neuroscience and, on occasion, Signal transduction, Glutamatergic and Glutamate receptor. His work carried out in the field of Endocytosis brings together such families of science as Transport protein, Arrestin, Desensitization, Scaffold protein and Intracellular.

This overview was generated by a machine learning system which analysed the scientist’s body of work. If you have any feedback, you can contact us here.

Best Publications

Evolving Concepts in G Protein-Coupled Receptor Endocytosis: The Role in Receptor Desensitization and Signaling

Stephen S. G. Ferguson.
Pharmacological Reviews (2001)

2304 Citations

Beta-arrestin-dependent formation of beta2 adrenergic receptor-Src protein kinase complexes.

L. M. Luttrell;S. S. G. Ferguson;Y. Daaka;W. E. Miller.
Science (1999)

1717 Citations

Role of β-Arrestin in Mediating Agonist-Promoted G Protein-Coupled Receptor Internalization

Stephen S. G. Ferguson;William E. Downey;Anne-Marie Colapietro;Larry S. Barak.
Science (1996)

1085 Citations

The β2-adrenergic receptor/βarrestin complex recruits the clathrin adaptor AP-2 during endocytosis

Stéphane A. Laporte;Robert H. Oakley;Jie Zhang;Jason A. Holt.
Proceedings of the National Academy of Sciences of the United States of America (1999)

758 Citations

Essential Role for G Protein-coupled Receptor Endocytosis in the Activation of Mitogen-activated Protein Kinase

Yehia Daaka;Louis M. Luttrell;Seungkirl Ahn;Gregory J. Della Rocca.
Journal of Biological Chemistry (1998)

648 Citations

Role for G protein-coupled receptor kinase in agonist-specific regulation of μ-opioid receptor responsiveness

Jie Zhang;Stephen S. G. Ferguson;Larry S. Barak;Sobha R. Bodduluri.
Proceedings of the National Academy of Sciences of the United States of America (1998)

602 Citations

Dynamin and β-Arrestin Reveal Distinct Mechanisms for G Protein-coupled Receptor Internalization

Jie Zhang;Stephen S.G. Ferguson;Larry S. Barak;Luc Ménard.
Journal of Biological Chemistry (1996)

578 Citations

A β-Arrestin/Green Fluorescent Protein Biosensor for Detecting G Protein-coupled Receptor Activation

Larry S. Barak;Stephen S.G. Ferguson;Jie Zhang;Marc G. Caron.
Journal of Biological Chemistry (1997)

556 Citations

G-protein-coupled receptor regulation: role of G-protein-coupled receptor kinases and arrestins

S. S. G. Ferguson;L. S. Barak;J. Zhang;M. G. Caron.
Canadian Journal of Physiology and Pharmacology (1996)

454 Citations

A central role for beta-arrestins and clathrin-coated vesicle-mediated endocytosis in beta2-adrenergic receptor resensitization. Differential regulation of receptor resensitization in two distinct cell types.

Jie Zhang;Larry S. Barak;Katharine E. Winkler;Marc G. Caron.
Journal of Biological Chemistry (1997)

345 Citations

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