His scientific interests lie mostly in Cell biology, G protein-coupled receptor, G protein-coupled receptor kinase, Arrestin and Signal transduction. Stephen S. G. Ferguson interconnects Endocytic cycle, Endocytosis and Internalization in the investigation of issues within Cell biology. His G protein-coupled receptor study incorporates themes from Heterotrimeric G protein and Enzyme-linked receptor.
His research investigates the connection between Heterotrimeric G protein and topics such as Rhodopsin-like receptors that intersect with issues in Small G Protein, GTP-binding protein regulators, Transport protein and PDZ domain. His work in G protein-coupled receptor kinase addresses issues such as Mitogen-activated protein kinase kinase, which are connected to fields such as MAP kinase kinase kinase. His Signal transduction research includes elements of Agonist, Receptor, Opioid peptide and Pharmacology.
Stephen S. G. Ferguson focuses on Cell biology, G protein-coupled receptor, Receptor, Biochemistry and Signal transduction. His Cell biology research is multidisciplinary, incorporating perspectives in Internalization, Endocytosis and Metabotropic glutamate receptor. His G protein-coupled receptor study combines topics in areas such as Heterotrimeric G protein, G protein and Rhodopsin-like receptors.
In his research, Agonist is intimately related to Pharmacology, which falls under the overarching field of Receptor. In the subject of general Signal transduction, his work in Cell signaling is often linked to Green fluorescent protein, thereby combining diverse domains of study. Stephen S. G. Ferguson has included themes like 5-HT5A receptor, Enzyme-linked receptor and Beta adrenergic receptor kinase in his G protein-coupled receptor kinase study.
His primary areas of study are Cell biology, G protein-coupled receptor, Metabotropic glutamate receptor 5, Receptor and Endocytosis. His research is interdisciplinary, bridging the disciplines of HEK 293 cells and Cell biology. His biological study spans a wide range of topics, including Heterotrimeric G protein, Cell type and GTPase-activating protein.
His Metabotropic glutamate receptor 5 research incorporates elements of Metabotropic glutamate receptor 4, Neuroscience, Metabotropic glutamate receptor 7 and Metabotropic glutamate receptor 3. As a member of one scientific family, Stephen S. G. Ferguson mostly works in the field of Receptor, focusing on Endocrinology and, on occasion, G protein-coupled receptor kinase, Sensitization and Excitatory postsynaptic potential. His research investigates the link between Endocytosis and topics such as Intracellular that cross with problems in Arrestin, Transport protein, Desensitization, Rab and GTPase.
Stephen S. G. Ferguson spends much of his time researching Cell biology, Receptor, G protein-coupled receptor, Metabotropic glutamate receptor 5 and Endocytosis. Stephen S. G. Ferguson is interested in Phosphorylation, which is a field of Cell biology. His studies deal with areas such as Endocrinology and GSK-3 as well as Receptor.
His study on G protein-coupled receptor is covered under Biochemistry. As a part of the same scientific family, Stephen S. G. Ferguson mostly works in the field of Metabotropic glutamate receptor 5, focusing on Neuroscience and, on occasion, Signal transduction, Glutamatergic and Glutamate receptor. His work carried out in the field of Endocytosis brings together such families of science as Transport protein, Arrestin, Desensitization, Scaffold protein and Intracellular.
This overview was generated by a machine learning system which analysed the scientist’s body of work. If you have any feedback, you can contact us here.
Evolving Concepts in G Protein-Coupled Receptor Endocytosis: The Role in Receptor Desensitization and Signaling
Stephen S. G. Ferguson.
Pharmacological Reviews (2001)
Beta-arrestin-dependent formation of beta2 adrenergic receptor-Src protein kinase complexes.
L. M. Luttrell;S. S. G. Ferguson;Y. Daaka;W. E. Miller.
Science (1999)
Role of β-Arrestin in Mediating Agonist-Promoted G Protein-Coupled Receptor Internalization
Stephen S. G. Ferguson;William E. Downey;Anne-Marie Colapietro;Larry S. Barak.
Science (1996)
The β2-adrenergic receptor/βarrestin complex recruits the clathrin adaptor AP-2 during endocytosis
Stéphane A. Laporte;Robert H. Oakley;Jie Zhang;Jason A. Holt.
Proceedings of the National Academy of Sciences of the United States of America (1999)
Essential Role for G Protein-coupled Receptor Endocytosis in the Activation of Mitogen-activated Protein Kinase
Yehia Daaka;Louis M. Luttrell;Seungkirl Ahn;Gregory J. Della Rocca.
Journal of Biological Chemistry (1998)
Role for G protein-coupled receptor kinase in agonist-specific regulation of μ-opioid receptor responsiveness
Jie Zhang;Stephen S. G. Ferguson;Larry S. Barak;Sobha R. Bodduluri.
Proceedings of the National Academy of Sciences of the United States of America (1998)
Dynamin and β-Arrestin Reveal Distinct Mechanisms for G Protein-coupled Receptor Internalization
Jie Zhang;Stephen S.G. Ferguson;Larry S. Barak;Luc Ménard.
Journal of Biological Chemistry (1996)
A β-Arrestin/Green Fluorescent Protein Biosensor for Detecting G Protein-coupled Receptor Activation
Larry S. Barak;Stephen S.G. Ferguson;Jie Zhang;Marc G. Caron.
Journal of Biological Chemistry (1997)
G-protein-coupled receptor regulation: role of G-protein-coupled receptor kinases and arrestins
S. S. G. Ferguson;L. S. Barak;J. Zhang;M. G. Caron.
Canadian Journal of Physiology and Pharmacology (1996)
A central role for beta-arrestins and clathrin-coated vesicle-mediated endocytosis in beta2-adrenergic receptor resensitization. Differential regulation of receptor resensitization in two distinct cell types.
Jie Zhang;Larry S. Barak;Katharine E. Winkler;Marc G. Caron.
Journal of Biological Chemistry (1997)
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