Joyce A. Goldstein

Overview

Best Publications

• The major genetic defect responsible for the polymorphism of S-mephenytoin metabolism in humans.

  S. M. F. De Morais;G. R. Wilkinson;J. Blaisdell;K. Nakamura

  1307
  Citations

• IDENTIFICATION OF A NEW GENETIC DEFECT RESPONSIBLE FOR THE POLYMORPHISM OF (S)-MEPHENYTOIN METABOLISM IN JAPANESE

  S. M. F. De Morais;G. R. Wilkinson;J. Blaisdell;U. A. Meyer

  1012
  Citations

• Cytochrome P450 2C9 polymorphisms: a comprehensive review of the in-vitro and human data.

  Craig R Lee;Joyce A Goldstein;John A Pieper

  890
  Citations

• Clinical relevance of genetic polymorphisms in the human CYP2C subfamily

  Joyce A. Goldstein

  863
  Citations

• The role of the CYP2C9-Leu359 allelic variant in the tolbutamide polymorphism.

  Theresa H. Sullivan-Klose;Burhan I. Ghanayem;Douglas A. Bell;Zhi Yi Zhang

  822
  Citations

• Biochemistry and molecular biology of the human CYP2C subfamily.

  Joyce A. Goldstein;Sonia M. F. de Morais

  710
  Citations

• Polymorphisms in human CYP2C8 decrease metabolism of the anticancer drug paclitaxel and arachidonic acid.

  Ding Dai;Darryl C. Zeldin;Joyce A. Blaisdell;Brian Chanas

  601
  Citations

• Frequencies of the defective CYP2C19 alleles responsible for the mephenytoin poor metabolizer phenotype in various Oriental, Caucasian, Saudi Arabian and American black populations.

  Joyce A. Goldstein;Takashi Ishizaki;Kan Chiba;Sonia M.F. de Morais

  481
  Citations

• Identification of Variants of CYP3A4 and Characterization of Their Abilities to Metabolize Testosterone and Chlorpyrifos

  Diana Dai;Jun Tang;Randy Rose;Ernest Hodgson

  475
  Citations

• Evidence that CYP2C19 is the major (S)-mephenytoin 4'-hydroxylase in humans

  J A Goldstein;M B Faletto;M Romkes-Sparks;T Sullivan

  470
  Citations

• Kidney Function Influences Warfarin Responsiveness and Hemorrhagic Complications

  Nita A. Limdi;T. Mark Beasley;Melissa F. Baird;Joyce A. Goldstein

  382
  Citations

• Cloning and expression of complementary DNAs for multiple members of the human cytochrome P450 2C subfamily

  Joyce A. Goldstein;Marjorie Romkes-Sparks

  348
  Citations

• Identification of a null allele of CYP2C9 in an African-American exhibiting toxicity to phenytoin.

  Robert S. Kidd;Timothy B. Curry;Susan Gallagher;Timi Edeki

  333
  Citations

• Influence of CYP2C9 and VKORC1 1173C/T genotype on the risk of hemorrhagic complications in African-American and European-American patients on warfarin.

  NA Limdi;G McGwin;JA Goldstein;TM Beasley

  331
  Citations

• Separation of pure polychlorinated biphenyl isomers into two types of inducers on the basis of induction of cytochrome P-450 or P-448

  Joyce A. Goldstein;Patricia Hickman;Hinda Bergman;James D. Mckinney

  296
  Citations

• Metabolism of chlorpyrifos by human cytochrome P450 isoforms and human, mouse, and rat liver microsomes.

  Jun Tang;Yan Cao;Randy L. Rose;Alan A. Brimfield

  288
  Citations

• A New Genetic Defect in Human CYP2C19: Mutation of the Initiation Codon Is Responsible for Poor Metabolism of S-Mephenytoin

  R. J. Ferguson;S. M. F. De Morais;S. Benhamou;C. Bouchardy

  280
  Citations

• Induction of human CYP2C9 by rifampicin, hyperforin, and phenobarbital is mediated by the pregnane X receptor.

  Yuping Chen;Stephen S. Ferguson;Masahiko Negishi;Joyce A. Goldstein

  275
  Citations

• Gene structure of CYP2C8 and extrahepatic distribution of the human CYP2Cs.

  Theresa S. Klose;Joyce A. Blaisdell;Joyce A. Goldstein

  255
  Citations

• Differences in the incidence of the CYP2C19 polymorphism affecting the S-mephenytoin phenotype in Chinese Han and Bai populations and identification of a new rare CYP2C19 mutant allele.

  Zhou-Sheng Xiao;Joyce A. Goldstein;Hong-Guang Xie;Joyce Blaisdell

  252
  Citations