What is he best known for?
The fields of study he is best known for:
- Internal medicine
- Cancer
- Pharmacology
Jos H. Beijnen mostly deals with Pharmacology, Pharmacokinetics, Internal medicine, Chemotherapy and Paclitaxel.
His work carried out in the field of Pharmacology brings together such families of science as P-glycoprotein and Docetaxel.
His P-glycoprotein research focuses on Abcg2 and how it connects with Tyrosine-kinase inhibitor.
His Pharmacokinetics study combines topics from a wide range of disciplines, such as Metabolite, Toxicity, In vivo and Dosing.
His Internal medicine study integrates concerns from other disciplines, such as Gastroenterology, Endocrinology, Immunology and Oncology.
His Drug research incorporates elements of CYP3A4, Pharmacogenetics and Pharmacotherapy.
His most cited work include:
- Disruption of the mouse mdr1a P-glycoprotein gene leads to a deficiency in the blood-brain barrier and to increased sensitivity to drugs (1972 citations)
- Limited oral bioavailability and active epithelial excretion of paclitaxel (Taxol) caused by P-glycoprotein in the intestine (770 citations)
- The breast cancer resistance protein protects against a major chlorophyll-derived dietary phototoxin and protoporphyria (674 citations)
What are the main themes of his work throughout his whole career to date?
The scientist’s investigation covers issues in Pharmacology, Pharmacokinetics, Chromatography, Internal medicine and Oncology.
His research in Pharmacology intersects with topics in Paclitaxel and Toxicity.
His Pharmacokinetics research integrates issues from Metabolite and Chemotherapy, Docetaxel.
His studies examine the connections between Metabolite and genetics, as well as such issues in Urine, with regards to Excretion.
His studies in Internal medicine integrate themes in fields like Gastroenterology and Endocrinology.
He focuses mostly in the field of Bioanalysis, narrowing it down to topics relating to Protein precipitation and, in certain cases, Triple quadrupole mass spectrometer.
He most often published in these fields:
- Pharmacology (54.82%)
- Pharmacokinetics (51.90%)
- Chromatography (45.28%)
What were the highlights of his more recent work (between 2015-2021)?
- Pharmacokinetics (51.90%)
- Pharmacology (54.82%)
- Internal medicine (29.70%)
In recent papers he was focusing on the following fields of study:
Jos H. Beijnen focuses on Pharmacokinetics, Pharmacology, Internal medicine, Chromatography and Oncology.
The Pharmacokinetics study which covers Dosing that intersects with Urology.
His study in Pharmacology focuses on Oral administration in particular.
Many of his studies on Internal medicine involve topics that are commonly interrelated, such as Gastroenterology.
His study in Oncology is interdisciplinary in nature, drawing from both Cohort, Dihydropyrimidine dehydrogenase, DPYD, Prostate cancer and Drug.
His work in Liquid chromatography–mass spectrometry addresses subjects such as Tandem mass spectrometry, which are connected to disciplines such as Detection limit and Metabolite.
Between 2015 and 2021, his most popular works were:
- Upfront Genotyping of DPYD*2A to Individualize Fluoropyrimidine Therapy: A Safety and Cost Analysis (153 citations)
- Phase II Study of WEE1 Inhibitor AZD1775 Plus Carboplatin in Patients With TP53-Mutated Ovarian Cancer Refractory or Resistant to First-Line Therapy Within 3 Months (113 citations)
- An Acquired Vulnerability of Drug-Resistant Melanoma with Therapeutic Potential (112 citations)
In his most recent research, the most cited papers focused on:
- Internal medicine
- Cancer
- Enzyme
Jos H. Beijnen spends much of his time researching Pharmacology, Pharmacokinetics, Internal medicine, Oncology and Chromatography.
His biological study focuses on Drug.
His studies deal with areas such as Uridine triphosphate, Intracellular and Deoxyuridine as well as Pharmacokinetics.
His Internal medicine study combines topics in areas such as Gastroenterology and Genotype.
His research investigates the connection between Oncology and topics such as Clinical trial that intersect with issues in Patient safety.
His biological study spans a wide range of topics, including Metabolite, Detection limit and High-performance liquid chromatography.
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