2023 - Research.com Medicine in Netherlands Leader Award
2010 - Royal Netherlands Academy of Arts and Sciences
Jos H. Beijnen mostly deals with Pharmacology, Pharmacokinetics, Internal medicine, Chemotherapy and Paclitaxel. His work carried out in the field of Pharmacology brings together such families of science as P-glycoprotein and Docetaxel. His P-glycoprotein research focuses on Abcg2 and how it connects with Tyrosine-kinase inhibitor.
His Pharmacokinetics study combines topics from a wide range of disciplines, such as Metabolite, Toxicity, In vivo and Dosing. His Internal medicine study integrates concerns from other disciplines, such as Gastroenterology, Endocrinology, Immunology and Oncology. His Drug research incorporates elements of CYP3A4, Pharmacogenetics and Pharmacotherapy.
The scientist’s investigation covers issues in Pharmacology, Pharmacokinetics, Chromatography, Internal medicine and Oncology. His research in Pharmacology intersects with topics in Paclitaxel and Toxicity. His Pharmacokinetics research integrates issues from Metabolite and Chemotherapy, Docetaxel.
His studies examine the connections between Metabolite and genetics, as well as such issues in Urine, with regards to Excretion. His studies in Internal medicine integrate themes in fields like Gastroenterology and Endocrinology. He focuses mostly in the field of Bioanalysis, narrowing it down to topics relating to Protein precipitation and, in certain cases, Triple quadrupole mass spectrometer.
Jos H. Beijnen focuses on Pharmacokinetics, Pharmacology, Internal medicine, Chromatography and Oncology. The Pharmacokinetics study which covers Dosing that intersects with Urology. His study in Pharmacology focuses on Oral administration in particular.
Many of his studies on Internal medicine involve topics that are commonly interrelated, such as Gastroenterology. His study in Oncology is interdisciplinary in nature, drawing from both Cohort, Dihydropyrimidine dehydrogenase, DPYD, Prostate cancer and Drug. His work in Liquid chromatography–mass spectrometry addresses subjects such as Tandem mass spectrometry, which are connected to disciplines such as Detection limit and Metabolite.
Jos H. Beijnen spends much of his time researching Pharmacology, Pharmacokinetics, Internal medicine, Oncology and Chromatography. His biological study focuses on Drug. His studies deal with areas such as Uridine triphosphate, Intracellular and Deoxyuridine as well as Pharmacokinetics.
His Internal medicine study combines topics in areas such as Gastroenterology and Genotype. His research investigates the connection between Oncology and topics such as Clinical trial that intersect with issues in Patient safety. His biological study spans a wide range of topics, including Metabolite, Detection limit and High-performance liquid chromatography.
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Disruption of the mouse mdr1a P-glycoprotein gene leads to a deficiency in the blood-brain barrier and to increased sensitivity to drugs
A.H. Schinkel;J.J.M. Smit;O. van Tellingen;J.H. Beijnen.
Limited oral bioavailability and active epithelial excretion of paclitaxel (Taxol) caused by P-glycoprotein in the intestine
A. Sparreboom;J. van Asperen;U. Mayer;A.H. Schinkel.
Proceedings of the National Academy of Sciences of the United States of America (1997)
A Phase I and Pharmacological Study with Imidazolium-trans-DMSO-imidazole-tetrachlororuthenate, a Novel Ruthenium Anticancer Agent
Jeany M. Rademaker-Lakhai;Desiree van den Bongard;Dick Pluim;Jos H. Beijnen.
Clinical Cancer Research (2004)
The breast cancer resistance protein protects against a major chlorophyll-derived dietary phototoxin and protoporphyria
Johan W. Jonker;Marije Buitelaar;Els Wagenaar;Martin A. van der Valk.
Proceedings of the National Academy of Sciences of the United States of America (2002)
Role of Breast Cancer Resistance Protein in the Bioavailability and Fetal Penetration of Topotecan
Johan W. Jonker;Johan W. Smit;Remco F. Brinkhuis;Marc Maliepaard.
Journal of the National Cancer Institute (2000)
A phase I study of the natural killer T-cell ligand alpha-galactosylceramide (KRN7000) in patients with solid tumors.
Giuseppe Giaccone;Cornelis J. A. Punt;Yoshitaka Ando;Rita Ruijter.
Clinical Cancer Research (2002)
An update on in vitro test methods in human hepatic drug biotransformation research: pros and cons.
Esther F.A Brandon;Christiaan D Raap;Irma Meijerman;Jos H Beijnen;Jos H Beijnen.
Toxicology and Applied Pharmacology (2003)
Miltefosine: a review of its pharmacology and therapeutic efficacy in the treatment of leishmaniasis
Thomas P. C. Dorlo;Thomas P. C. Dorlo;Manica Balasegaram;Jos H. Beijnen;Peter J. de Vries.
Journal of Antimicrobial Chemotherapy (2012)
Stable isotopically labeled internal standards in quantitative bioanalysis using liquid chromatography/mass spectrometry: necessity or not?
Ellen Stokvis;Hilde Rosing;Jos H. Beijnen;Jos H. Beijnen.
Rapid Communications in Mass Spectrometry (2005)
Role of glutathione in the export of compounds from cells by the multidrug-resistance-associated protein
G J Zaman;J Lankelma;O van Tellingen;J Beijnen.
Proceedings of the National Academy of Sciences of the United States of America (1995)
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