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Microbiology

D-Index
54
Citations
10224
World Ranking
3969
National Ranking
354

Overview

Andrew M. L. Lever is affiliated with the University of Cambridge in the United Kingdom. Their research spans multiple areas broadly within Biochemistry, Genetics and Molecular Biology, Medicine, and Immunology and Microbiology, with a total of 25, 23, and 16 publications in these fields respectively.

The scientist's work covers key subfields including Molecular Biology, Infectious Diseases, Virology, Ocean Engineering, and Genetics. Research topics of focus include HIV Research and Treatment, RNA Interference and Gene Delivery, SARS-CoV-2 and COVID-19 Research, Cellular transport and secretion, CRISPR and Genetic Engineering, Virus-based gene therapy research, and Drilling and Well Engineering.

Andrew M. L. Lever has contributed to several notable papers, including:

  • Recurrent emergence and transmission of a SARS-CoV-2 spike deletion H69/V70, 2020, bioRxiv (Cold Spring Harbor Laboratory)
  • Antiretroviral therapy alone versus antiretroviral therapy with a kick and kill approach, on measures of the HIV reservoir in participants with recent HIV infection (the RIVER trial): a phase 2, randomised trial, 2020, The Lancet
  • Recurrent Emergence and Transmission of a SARS-CoV-2 Spike Deletion H69/V70, 2021, SSRN Electronic Journal
  • The Interplay between ESCRT and Viral Factors in the Enveloped Virus Life Cycle, 2021, Viruses
  • ESCRT-II functions by linking to ESCRT-I in human immunodeficiency virus-1 budding, 2020, Cellular Microbiology

The frequent co-authors associated with their publications include:

  • Julia C. Kenyon
  • Sarah Fidler
  • John Frater
  • Bo Meng
  • Wolfgang Stöhr

Andrew M. L. Lever has published extensively in various research venues. The most frequent publication outlets include:

  • bioRxiv (Cold Spring Harbor Laboratory)
  • Viruses
  • Zenodo (CERN European Organization for Nuclear Research)
  • Nature
  • UNC Libraries

The research output reflects a multidisciplinary approach spanning molecular and clinical aspects of infectious diseases, specifically focusing on viral pathogens such as HIV and SARS-CoV-2. Their work also explores cellular mechanisms related to virus-host interactions and gene delivery technologies, highlighting cross-disciplinary connections with genetic engineering and viral therapies.

Best Publications

  • HIV-1 remission following CCR5Δ32/Δ32 haematopoietic stem-cell transplantation

    Ravindra K. Gupta;Sultan Abdul-Jawad;Laura E. McCoy;Hoi Ping Mok

  • Identification of a sequence required for efficient packaging of human immunodeficiency virus type 1 RNA into virions.

    A Lever;H Gottlinger;W Haseltine;J Sodroski

  • Recurrent emergence of SARS-CoV-2 spike deletion H69/V70 and its role in the Alpha variant B.1.1.7.

    Bo Meng;Steven A Kemp;Steven A Kemp;Guido Papa;Rawlings Datir

  • The human immunodeficiency virus type 1 packaging signal and major splice donor region have a conserved stable secondary structure.

    G. P. Harrison;A. M. L. Lever

  • HIV Gag polyprotein: processing and early viral particle assembly

    Neil M. Bell;Andrew M.L. Lever

  • Non-adherent, low-density cells from human peripheral blood contain dendritic cells and monocytes, both with veiled morphology.

    S. C. Knight;J. Farrant;A. Bryant;A. J. Edwards

  • Non-A, non-B hepatitis occurring in agammaglobulinaemic patients after intravenous immunoglobulin

    A.M.L Lever;D Brown;A.D.B Webster;H.C Thomas

  • Rotaviruses Associate with Cellular Lipid Droplet Components To Replicate in Viroplasms, and Compounds Disrupting or Blocking Lipid Droplets Inhibit Viroplasm Formation and Viral Replication

    Winsome Cheung;Michael Gill;Alessandro Esposito;Clemens F. Kaminski

  • Gene transfer into human lymphocytes by a defective human immunodeficiency virus type 1 vector

    M Poznansky;A Lever;L Bergeron;W Haseltine

  • Effects of deletions in the cytoplasmic domain on biological functions of human immunodeficiency virus type 1 envelope glycoproteins.

    D H Gabuzda;A Lever;E Terwilliger;J Sodroski

  • Recurrent emergence and transmission of a SARS-CoV-2 Spike deletion ΔH69/V70

    Steven Kemp;Steven Kemp;Bo Meng;Isabella Ferreira;Rawlings Datir

  • Vectors containing hiv packaging sequences, packaging defective hiv vectors, and uses thereof

    Joseph G. Sodroski;William A. Haseltine;Mark Poznansky;Andrew Lever

  • Recurrent Emergence and Transmission of a SARS-CoV-2 Spike Deletion H69/V70

    S.A. Kemp;B. Meng;I.A.T.M. Ferriera;Rawlings Datir

  • HLA class I antigens on the hepatocyte membrane during recovery from acute hepatitis B virus infection and during interferon therapy in chronic hepatitis B virus infection.

    Massimo Pignatelli;Jenny Waters;Dave Brown;Andrew Lever

  • Evidence for a deficiency of interferon production in patients with chronic hepatitis B virus infection acquired in adult life.

    Tadashi Ikeda;Andrew M. L. Lever;Howard C. Thomas

  • Nonreciprocal Packaging of Human Immunodeficiency Virus Type 1 and Type 2 RNA: a Possible Role for the p2 Domain of Gag in RNA Encapsidation

    Jane F. Kaye;Andrew M. L. Lever

  • ALPHA-INTERFERON THERAPY FOR NON-A, NON-B HEPATITIS TRANSMITTED BY GAMMAGLOBULIN REPLACEMENT THERAPY

    B.J. Thomson;A.M.L. Lever;M. Doran;A.D.B. Webster

  • Packaging of human immunodeficiency virus type 1 RNA requires cis-acting sequences outside the 5' leader region.

    J. H. Richardson;L. A. Child;A. M. L. Lever

  • Pausing of reverse transcriptase on retroviral RNA templates is influenced by secondary structures both 5' and 3' of the catalytic site.

    Geoffrey P. Harrison;Matthew S. Mayo;Eric Hunter;Andrew M. L. Lever

  • HIV-1 Gag-RNA interaction occurs at a perinuclear/centrosomal site; analysis by confocal microscopy and FRET.

    Emma Poole;Padraig Strappe;Hoi-Ping Mok;Ray Hicks

Frequent Co-Authors

Joseph Sodroski
Joseph Sodroski Harvard Medical School
Eric Hunter
Eric Hunter Emory University
Mark A. Wainberg
Mark A. Wainberg McGill University
Mark R. Wills
Mark R. Wills University of Cambridge
Heinrich G. Göttlinger
Heinrich G. Göttlinger University of Massachusetts Chan Medical School
Graeme J. M. Alexander
Graeme J. M. Alexander University College London
Ben Berkhout
Ben Berkhout University of Amsterdam
John Frater
John Frater University of Oxford
Michael J. Gait
Michael J. Gait MRC Laboratory of Molecular Biology
Paul D. Griffiths
Paul D. Griffiths University College London

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