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Graeme J. M. Alexander

Graeme J. M. Alexander

D-Index & Metrics

Medicine

D-Index
90
Citations
36661
World Ranking
12067
National Ranking
1140

Overview

Graeme J. M. Alexander is affiliated with University College London in the United Kingdom. Their primary field of study is Medicine, with significant contributions in Hepatology, Epidemiology, Surgery, Nutrition and Dietetics, and Health, Toxicology and Mutagenesis.

The scientist's research topics focus on Liver Disease Diagnosis and Treatment, Hepatitis C virus research, Hepatocellular Carcinoma Treatment and Prognosis, Trace Elements in Health, Hepatitis B Virus Studies, Cholangiocarcinoma and Gallbladder Cancer Studies, and Heavy Metal Exposure and Toxicity.

Recent publications include the following:

  • Primary liver cancer in the UK: Incidence, incidence-based mortality, and survival by subtype, sex, and nation (2021) published in JHEP Reports
  • Investigation and management of Wilson's disease: a practical guide from the British Association for the Study of the Liver (2022) published in The Lancet. Gastroenterology & hepatology
  • Reduced circulating BMP10 and BMP9 and elevated endoglin are associated with disease severity, decompensation and pulmonary vascular syndromes in patients with cirrhosis (2020) published in EBioMedicine
  • Role of Hepatocyte Senescence in the Activation of Hepatic Stellate Cells and Liver Fibrosis Progression (2022) published in Cells
  • Regional variations in hepatocellular carcinoma incidence, routes to diagnosis, treatment and survival in England (2021) published in British Journal of Cancer

They have frequently published in venues such as:

  • Genes and Immunity
  • JHEP Reports
  • The Lancet. Gastroenterology & hepatology
  • Cells
  • EBioMedicine

Collaborations are notable with frequent co-authors including:

  • Anya Burton
  • Daniela Tataru
  • Ian Rowe
  • Aileen Marshall
  • Ana Valencia

Best Publications

  • Genetic variation in IL28B and spontaneous clearance of hepatitis C virus

    David L. Thomas;Chloe L Thio;Maureen P. Martin;Ying Qi

  • Early indicators of prognosis in fulminant hepatic failure

    John G. O'Grady;Graeme J.M. Alexander;Karen M. Hayllar;Roger Williams

  • HLA and NK Cell Inhibitory Receptor Genes in Resolving Hepatitis C Virus Infection

    Salim I. Khakoo;Chloe L. Thio;Maureen P. Martin;Collin R. Brooks

  • Liver Transplantation in European Patients with the Hepatitis B Surface Antigen

    Didier Samuel;Rainer Muller;Graeme Alexander;Luigi Fassati

  • Association of diabetes mellitus and chronic hepatitis C virus infection.

    Andrew L. Mason;Johnson Y. Lau;Nicole Hoang;KePing Qian

  • Targeted gene correction of α1-antitrypsin deficiency in induced pluripotent stem cells

    Kosuke Yusa;S. Tamir Rashid;Helene Strick-Marchand;Helene Strick-Marchand;Ignacio Varela

  • Improvement by acetylcysteine of hemodynamics and oxygen transport in fulminant hepatic failure.

    Phillip M. Harrison;Julia A. Wendon;Alexander E.S. Gimson;Graeme J.M. Alexander

  • Modeling inherited metabolic disorders of the liver using human induced pluripotent stem cells

    S. Tamir Rashid;Sebastien Corbineau;Nick Hannan;Stefan J. Marciniak

  • TM6SF2 rs58542926 influences hepatic fibrosis progression in patients with non-alcoholic fatty liver disease

    Yang-Lin Liu;Helen L Reeves;Alastair D Burt;Dina Tiniakos

  • Evidence for a link between hepatitis C virus infection and diabetes mellitus in a cirrhotic population

    Michael E.D. Allison;Tim Wreghitt;Chris R. Palmer;Graeme J.M. Alexander

  • 2016 Comprehensive Update of the Banff Working Group on Liver Allograft Pathology: Introduction of Antibody-Mediated Rejection.

    A J Demetris;C Bellamy;S G Hübscher;J O'Leary

  • Further evidence for an association between non-insulin-dependent diabetes mellitus and chronic hepatitis C virus infection.

    Simona Caronia;Kevin Taylor;Luigi Pagliaro;Colin Carr

  • Genome-wide association study identifies 12 new susceptibility loci for primary biliary cirrhosis

    George F Mells;James A B Floyd;Katherine I Morley;Katherine I Morley;Heather J Cordell

  • Hepatitis B virus reinfection after orthotopic liver transplantation. Serological and clinical implications.

    John G. O'Grady;Heather M. Smith;Susan E. Davies;Helena M. Daniels

  • Sex and Age Are Determinants of the Clinical Phenotype of Primary Biliary Cirrhosis and Response to Ursodeoxycholic Acid

    Marco Carbone;George F. Mells;Greta Pells;Muhammad F. Dawwas

  • Dense genotyping of immune-related disease regions identifies nine new risk loci for primary sclerosing cholangitis

    Jimmy Z Liu;Johannes Roksund Hov;Trine Folseraas;Trine Folseraas;Eva Ellinghaus

  • Prospective study of bacterial infection in acute liver failure: An analysis of fifty patients

    Nancy Rolando;Felicity Harvey;Javier Brahm;John Philpott-Howard

  • European collaborative study on factors influencing outcome after liver transplantation for hepatitis C

    Cyrille Féray;Lucio Caccamo;Graeme J.M. Alexander;Béatrice Ducot

  • Regulatory T cells suppress in vitro proliferation of virus-specific CD8+ T cells during persistent hepatitis C virus infection.

    Simon M. Rushbrook;Scott M. Ward;Esther Unitt;Sarah L. Vowler

  • Enhanced liver fibrosis test can predict clinical outcomes in patients with chronic liver disease

    Julie Parkes;Paul Roderick;Scott Harris;Christopher Day

Frequent Co-Authors

Roger Williams
Roger Williams Foundation for Liver Research
Gideon M. Hirschfield
Gideon M. Hirschfield University Health Network
Salim I. Khakoo
Salim I. Khakoo University of Southampton
David Jones
David Jones Newcastle University
Nicholas Coleman
Nicholas Coleman University of Cambridge
Heather J. Cordell
Heather J. Cordell Newcastle University
Tom H. Karlsen
Tom H. Karlsen Oslo University Hospital
James Neuberger
James Neuberger Queen Elizabeth Hospital Birmingham
Peter J. Friend
Peter J. Friend University of Oxford
Roger W. Chapman
Roger W. Chapman University of Oxford

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