His main research concerns Genome-wide association study, Primary sclerosing cholangitis, Immunology, Genetics and Inflammatory bowel disease. His study in Genome-wide association study is interdisciplinary in nature, drawing from both Disease, Genetic predisposition, Genetic association and Locus. His Primary sclerosing cholangitis study is related to the wider topic of Internal medicine.
His work on Human leukocyte antigen as part of general Immunology study is frequently linked to Alkaline phosphatase, therefore connecting diverse disciplines of science. His Genetics study incorporates themes from Inflammatory response and Primary biliary cirrhosis. As part of the same scientific family, Tom H. Karlsen usually focuses on Inflammatory bowel disease, concentrating on Allele and intersecting with Medical genetics, IRGM and Genetic architecture.
Tom H. Karlsen mainly investigates Primary sclerosing cholangitis, Internal medicine, Immunology, Gastroenterology and Genetics. His Primary sclerosing cholangitis research is multidisciplinary, incorporating perspectives in Liver transplantation, Inflammatory bowel disease and Ulcerative colitis. His Inflammatory bowel disease study combines topics in areas such as Crohn's disease and Pathogenesis.
His work on Liver disease, Hepatology, Framingham Risk Score and Cohort as part of his general Internal medicine study is frequently connected to In patient, thereby bridging the divide between different branches of science. His work in Immunology is not limited to one particular discipline; it also encompasses Allele. His Genome-wide association study study necessitates a more in-depth grasp of Single-nucleotide polymorphism.
His primary areas of study are Primary sclerosing cholangitis, Internal medicine, Inflammatory bowel disease, Gastroenterology and Pathology. Tom H. Karlsen interconnects Liver transplantation, Immunology, Bile acid, Ulcerative colitis and Fibrosis in the investigation of issues within Primary sclerosing cholangitis. The various areas that he examines in his Inflammatory bowel disease study include Ursodeoxycholic acid, Cirrhosis, Cancer and Genetic association.
His work carried out in the field of Pathology brings together such families of science as Natural killer T cell and Bile duct. His Human leukocyte antigen research focuses on subjects like Linkage disequilibrium, which are linked to Disease. He works mostly in the field of Disease, limiting it down to concerns involving Genome-wide association study and, occasionally, Case-control study.
His scientific interests lie mostly in Primary sclerosing cholangitis, Internal medicine, Microbiome, Framingham Risk Score and Cohort. Primary sclerosing cholangitis is a subfield of Pathology that Tom H. Karlsen tackles. The Internal medicine study combines topics in areas such as Gastroenterology and Locus.
He has included themes like Inflammatory bowel disease, Zonulin, Pathophysiology, CD14 and Concomitant in his Gastroenterology study. Tom H. Karlsen has researched Cohort in several fields, including Biliary disease, Liver transplantation, Human leukocyte antigen and Hazard ratio. His research integrates issues of RNA, Area under the curve, Colitis and Cancer research in his study of Ulcerative colitis.
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Host-microbe interactions have shaped the genetic architecture of inflammatory bowel disease
Luke Jostins;Stephan Ripke;Rinse K Weersma;Richard H Duerr.
Meta-analysis identifies 29 additional ulcerative colitis risk loci, increasing the number of confirmed associations to 47.
Carl A. Anderson;Gabrielle Boucher;Charlie W. Lees;Andre Franke.
Nature Genetics (2011)
Sequence variants in IL10, ARPC2 and multiple other loci contribute to ulcerative colitis susceptibility
Andre Franke;Tobias Balschun;Tom H Karlsen;Jurgita Sventoraityte.
Nature Genetics (2008)
Genomewide Association Study of Severe Covid-19 with Respiratory Failure.
David Ellinghaus;Frauke Degenhardt;Luis Bujanda;Maria Buti.
The New England Journal of Medicine (2020)
Primary sclerosing cholangitis
Gideon M Hirschfield;Tom H Karlsen;Tom H Karlsen;Keith D Lindor;David H Adams.
The Lancet (2013)
Replication of signals from recent studies of Crohn's disease identifies previously unknown disease loci for ulcerative colitis.
Andre Franke;Tobias Balschun;Tom H Karlsen;Jürgen Hedderich.
Nature Genetics (2008)
Analysis of five chronic inflammatory diseases identifies 27 new associations and highlights disease-specific patterns at shared loci
David Ellinghaus;Luke Jostins;Sarah L. Spain;Adrian Cortes.
Nature Genetics (2016)
The First European Evidence-Based Consensus on Extra-Intestinal Manifestations in Inflammatory Bowel Disease
Marcus Harbord;Vito Annese;Stephan R Vavricka;Matthieu Allez.
Journal of Crohns & Colitis (2016)
Genome-wide association analysis identifies variation in vitamin D receptor and other host factors influencing the gut microbiota
Jun Wang;Louise B Thingholm;Jurgita Skiecevičienė;Philipp Rausch;Philipp Rausch.
Nature Genetics (2016)
Genome-wide association study identifies a psoriasis susceptibility locus at TRAF3IP2
Eva Ellinghaus;David Ellinghaus;Philip E Stuart;Rajan P Nair.
Nature Genetics (2010)
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