World's Best Scientists 2026 revealed!
Ramnik J. Xavier

Ramnik J. Xavier

Award Badge
Best Scientists
2025
Award Badge
Immunology
USA
2026

D-Index & Metrics

Best Scientists

D-Index
182
Citations
187315
World Ranking
563
National Ranking
360

Immunology

D-Index
183
Citations
200653
World Ranking
28
National Ranking
19

Medicine

D-Index
185
Citations
204959
World Ranking
301
National Ranking
193

Research.com Recognitions

  • 2026 - Research.com Immunology in United States Leader Award
  • 2025 - Research.com Best Scientists Award
  • 2025 - Research.com Immunology in United States Leader Award
  • 2022 - Research.com Microbiology in United States Leader Award
  • Member of the Association of American Physicians
  • Member of the Association of American Physicians
  • Member of the Association of American Physicians
  • Member of the Association of American Physicians
  • Member of the Association of American Physicians

Overview

Ramnik J. Xavier is affiliated with the Broad Institute in the United States. Their research output spans major fields including Biochemistry, Genetics and Molecular Biology, as well as Medicine. Within these broad categories, their work is concentrated in subfields such as Molecular Biology, Immunology, Genetics, Epidemiology, and Surgery.

The scientist's research topics include:

  • Gut microbiota and health
  • Inflammatory Bowel Disease
  • Immune Cell Function and Interaction
  • Single-cell and spatial transcriptomics
  • IL-33, ST2, and ILC Pathways
  • Microscopic Colitis
  • T-cell and B-cell Immunology

Xavier has published extensively in key venues, with frequent contributions to:

  • bioRxiv (Cold Spring Harbor Laboratory)
  • University of Groningen research database (University of Groningen / Centre for Information Technology)
  • Gastroenterology
  • Nature
  • Nature Communications

Notable recent papers include:

  • Defining trained immunity and its role in health and disease, 2020, Nature Reviews. Immunology
  • Structure-based protein function prediction using graph convolutional networks, 2021, Nature Communications
  • Pathway paradigms revealed from the genetics of inflammatory bowel disease, 2020, Nature
  • Genome-wide enhancer maps link risk variants to disease genes, 2021, Nature
  • Novel bile acid biosynthetic pathways are enriched in the microbiome of centenarians, 2021, Nature

Frequent collaborators include:

  • Hera Vlamakis
  • Daniel B. Graham
  • Leo A. B. Joosten
  • Ashwin N. Ananthakrishnan
  • Mihai G. Netea

Among professional recognitions, Ramnik J. Xavier is a member of the Association of American Physicians, an affiliation that signifies a level of peer acknowledgment within the medical research community.

Best Publications

  • Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition)

    Daniel J. Klionsky;Amal Kamal Abdel-Aziz;Sara Abdelfatah;Mahmoud Abdellatif

  • Guidelines for the use and interpretation of assays for monitoring autophagy

    Daniel J. Klionsky;Fabio C. Abdalla;Hagai Abeliovich;Robert T. Abraham

  • Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)

    Daniel J. Klionsky;Kotb Abdelmohsen;Akihisa Abe;Joynal Abedin

  • Unravelling the pathogenesis of inflammatory bowel disease

    R. J. Xavier;Daniel K Podolsky

  • Host-microbe interactions have shaped the genetic architecture of inflammatory bowel disease

    Luke Jostins;Stephan Ripke;Rinse K Weersma;Richard H Duerr

  • Succinate is an inflammatory signal that induces IL-1β through HIF-1α

    G. M. Tannahill;A. M. Curtis;J. Adamik;E. M. Palsson-McDermott

  • The Treatment-Naive Microbiome in New-Onset Crohn’s Disease

    Dirk Gevers;Subra Kugathasan;Lee A. Denson;Yoshiki Vázquez-Baeza

  • Regulation of inflammatory responses by gut microbiota and chemoattractant receptor GPR43

    Kendle M. Maslowski;Angelica T. Vieira;Angelica T. Vieira;Aylwin Ng;Jan Kranich

  • Genetics and pathogenesis of inflammatory bowel disease

    Bernard Khor;Agnès Gardet;Ramnik J. Xavier;Ramnik J. Xavier

  • Genome-wide association defines more than 30 distinct susceptibility loci for Crohn's disease

    Jeffrey C. Barrett;Sarah Hansoul;Dan L. Nicolae;Judy H. Cho

  • Dysfunction of the intestinal microbiome in inflammatory bowel disease and treatment

    Xochitl C Morgan;Timothy L Tickle;Timothy L Tickle;Harry Sokol;Harry Sokol;Dirk Gevers

  • Multi-omics of the gut microbial ecosystem in inflammatory bowel diseases.

    Jason Lloyd-Price;Jason Lloyd-Price;Cesar Arze;Ashwin N. Ananthakrishnan;Melanie Schirmer;Melanie Schirmer

  • Trained immunity: A program of innate immune memory in health and disease

    Mihai G. Netea;Leo A. B. Joosten;Eicke Latz;Kingston H. G. Mills

  • SARS-CoV-2 Receptor ACE2 Is an Interferon-Stimulated Gene in Human Airway Epithelial Cells and Is Detected in Specific Cell Subsets across Tissues.

    Carly G.K. Ziegler;Samuel J. Allon;Sarah K. Nyquist;Ian M. Mbano

  • Defining trained immunity and its role in health and disease

    Mihai G. Netea;Mihai G. Netea;Jorge Domínguez-Andrés;Luis B. Barreiro;Luis B. Barreiro;Triantafyllos Chavakis;Triantafyllos Chavakis

  • CRISPR-Cas9 Knockin Mice for Genome Editing and Cancer Modeling

    Randall J. Platt;Sidi Chen;Yang Zhou;Michael J. Yim

  • mTOR- and HIF-1α–mediated aerobic glycolysis as metabolic basis for trained immunity

    Shih-Chin Cheng;Jessica Quintin;Robert A. Cramer;Kelly M. Shepardson

  • Succinate Dehydrogenase Supports Metabolic Repurposing of Mitochondria to Drive Inflammatory Macrophages

    Evanna L. Mills;Beth Kelly;Angela Logan;Ana S.H. Costa

  • Genome-wide association study identifies new susceptibility loci for Crohn disease and implicates autophagy in disease pathogenesis

    John D. Rioux;John D. Rioux;Ramnik J. Xavier;Kent D. Taylor;Mark S. Silverberg

  • The Microbiome in Inflammatory Bowel Disease: Current Status and the Future Ahead

    Aleksandar D. Kostic;Ramnik J. Xavier;Ramnik J. Xavier;Dirk Gevers

Frequent Co-Authors

Curtis Huttenhower
Curtis Huttenhower Harvard University
Mark J. Daly
Mark J. Daly Massachusetts General Hospital
Hera Vlamakis
Hera Vlamakis Broad Institute
Ashwin N. Ananthakrishnan
Ashwin N. Ananthakrishnan Harvard University
Aylwin Ng
Aylwin Ng Harvard University
Cisca Wijmenga
Cisca Wijmenga University Medical Center Groningen
Mihai G. Netea
Mihai G. Netea Radboud University
John D. Rioux
John D. Rioux University of Montreal
Daniel K. Podolsky
Daniel K. Podolsky The University of Texas at Dallas
Eric A. Franzosa
Eric A. Franzosa Harvard University

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