His scientific interests lie mostly in Cell biology, Genetics, Innate immune system, Gene and Gene expression. His Cell biology research incorporates themes from BAG3 and Necroptosis. As part of his studies on Genetics, he often connects relevant subjects like Immunology.
His Innate immune system research is multidisciplinary, relying on both Secondary infection, Protein kinase B, Anaerobic glycolysis and Immunity. His biological study spans a wide range of topics, including Crohn's disease, IRGM and ATG16L1. His Gene expression research includes elements of RNA, Transcription factor, Blood cell, Monocyte and Epigenetics.
His primary scientific interests are in Cell biology, Genetics, Immunology, Immune system and Gene. Aylwin Ng has researched Cell biology in several fields, including Innate immune system, Ubiquitin, BAG3 and Mitophagy. His Innate immune system research is multidisciplinary, incorporating elements of Secondary infection, Transcription factor, Ubiquitin ligase and Anaerobic glycolysis.
His Genetics research incorporates elements of Disease and ATG16L1. His Immunology study incorporates themes from Receptor and Candida albicans. The various areas that he examines in his Gene study include Virus and Virology.
Aylwin Ng mostly deals with Immune system, Cell biology, Computational biology, Immunology and Genetics. His Immune system research is multidisciplinary, incorporating perspectives in ATG16L1, Genetic association and Genotype. His research in Cell biology intersects with topics in Innate immune system, Ubiquitin ligase and Cytokine.
The concepts of his Computational biology study are interwoven with issues in Regulator, CRISPR and Functional genomics. His research integrates issues of Cancer research, IRF1 and Inflammatory bowel disease in his study of Immunology. His study in the field of Gene, Genetic variation, Kinase and Phosphorylation is also linked to topics like Translational regulation.
Aylwin Ng focuses on Immune system, Computational biology, Functional genomics, Systems biology and IRF1. His Immune system study combines topics in areas such as Inflammation, Antigen and Virulence. Aylwin Ng interconnects Regulator, RNA interference, Genome editing, Unfolded protein response and Regulation of gene expression in the investigation of issues within Computational biology.
Aylwin Ng has included themes like Immunology, Effector, Immunity, Disease and Regulatory T cell in his IRF1 study. His Immunity study combines topics from a wide range of disciplines, such as Virus, Interferon, Virology and Pathogen.
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Regulation of inflammatory responses by gut microbiota and chemoattractant receptor GPR43
Kendle M. Maslowski;Angelica T. Vieira;Angelica T. Vieira;Aylwin Ng;Jan Kranich.
Nature (2009)
Meta-analysis identifies 29 additional ulcerative colitis risk loci, increasing the number of confirmed associations to 47.
Carl A. Anderson;Gabrielle Boucher;Charlie W. Lees;Andre Franke.
Nature Genetics (2011)
mTOR- and HIF-1α–mediated aerobic glycolysis as metabolic basis for trained immunity
Shih-Chin Cheng;Jessica Quintin;Robert A. Cramer;Kelly M. Shepardson.
(2014)
Epigenetic programming of monocyte-to-macrophage differentiation and trained innate immunity
Sadia Saeed;Jessica Quintin;Hindrik H. D. Kerstens;Nagesha A. Rao.
(2014)
Identification of a Molecular Signaling Network that Regulates a Cellular Necrotic Cell Death Pathway
Junichi Hitomi;Dana E. Christofferson;Aylwin Ng;Jianhua Yao.
Cell (2008)
Virus-plus-susceptibility gene interaction determines Crohn's disease gene Atg16L1 phenotypes in intestine
Ken Cadwell;Khushbu K. Patel;Nicole S. Maloney;Ta Chiang Liu.
Cell (2010)
Genome-wide analysis reveals mechanisms modulating autophagy in normal brain aging and in Alzheimer's disease
Marta M. Lipinski;Bin Zheng;Tao Lu;Zhenyu Yan.
Proceedings of the National Academy of Sciences of the United States of America (2010)
RNA interference screen for human genes associated with West Nile virus infection.
Manoj N Krishnan;Aylwin Ng;Bindu Sukumaran;Felicia D Gilfoy.
Nature (2008)
CASPASE 8 inhibits programmed necrosis by processing CYLD
Marie Anne O’Donnell;Eva Perez-Jimenez;Andrew Oberst;Aylwin Ng.
Nature Cell Biology (2011)
Identifying Relationships among Genomic Disease Regions: Predicting Genes at Pathogenic SNP Associations and Rare Deletions
Soumya Raychaudhuri;Robert M. Plenge;Robert M. Plenge;Robert M. Plenge;Elizabeth J. Rossin;Elizabeth J. Rossin;Elizabeth J. Rossin;Aylwin C. Y. Ng.
PLOS Genetics (2009)
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