Aylwin Ng

Overview

Best Publications

• Regulation of inflammatory responses by gut microbiota and chemoattractant receptor GPR43

  Kendle M. Maslowski;Angelica T. Vieira;Angelica T. Vieira;Aylwin Ng;Jan Kranich

  3483
  Citations

• mTOR- and HIF-1α–mediated aerobic glycolysis as metabolic basis for trained immunity

  Shih-Chin Cheng;Jessica Quintin;Robert A. Cramer;Kelly M. Shepardson

  2188
  Citations

• Epigenetic programming of monocyte-to-macrophage differentiation and trained innate immunity

  Sadia Saeed;Jessica Quintin;Hindrik H. D. Kerstens;Nagesha A. Rao

  1727
  Citations

• Meta-analysis identifies 29 additional ulcerative colitis risk loci, increasing the number of confirmed associations to 47.

  Carl A. Anderson;Gabrielle Boucher;Charlie W. Lees;Andre Franke

  1676
  Citations

• Identification of a Molecular Signaling Network that Regulates a Cellular Necrotic Cell Death Pathway

  Junichi Hitomi;Dana E. Christofferson;Aylwin Ng;Jianhua Yao

  1145
  Citations

• Virus-plus-susceptibility gene interaction determines Crohn's disease gene Atg16L1 phenotypes in intestine

  Ken Cadwell;Khushbu K. Patel;Nicole S. Maloney;Ta Chiang Liu

  1014
  Citations

• Genome-wide analysis reveals mechanisms modulating autophagy in normal brain aging and in Alzheimer's disease

  Marta M. Lipinski;Bin Zheng;Tao Lu;Zhenyu Yan

  719
  Citations

• RNA interference screen for human genes associated with West Nile virus infection.

  Manoj N Krishnan;Aylwin Ng;Bindu Sukumaran;Felicia D Gilfoy

  625
  Citations

• CASPASE 8 inhibits programmed necrosis by processing CYLD

  Marie Anne O’Donnell;Eva Perez-Jimenez;Andrew Oberst;Aylwin Ng

  610
  Citations

• Identifying Relationships among Genomic Disease Regions: Predicting Genes at Pathogenic SNP Associations and Rare Deletions

  Soumya Raychaudhuri;Robert M. Plenge;Robert M. Plenge;Robert M. Plenge;Elizabeth J. Rossin;Elizabeth J. Rossin;Elizabeth J. Rossin;Aylwin C. Y. Ng

  499
  Citations

• Image-based genome-wide siRNA screen identifies selective autophagy factors

  Anthony Orvedahl;Rhea Sumpter;Guanghua Xiao;Aylwin Ng;Aylwin Ng

  497
  Citations

• Reovirus infection triggers inflammatory responses to dietary antigens and development of celiac disease

  Romain Bouziat;Reinhard Hinterleitner;Judy J. Brown;Jennifer E. Stencel-Baerenwald

  493
  Citations

• A genome-wide genetic screen for host factors required for hepatitis C virus propagation

  Qisheng Li;Abraham L. Brass;Aylwin Ng;Zongyi Hu

  421
  Citations

• The tumour suppressor CYLD is a negative regulator of RIG-I-mediated antiviral response

  Constantin S Friedman;Marie Anne O'Donnell;Diana Legarda‐Addison;Aylwin Ng

  394
  Citations

• High-density mapping of the MHC identifies a shared role for HLA-DRB1∗01:03 in inflammatory bowel diseases and heterozygous advantage in ulcerative colitis

  Philippe Goyette;Gabrielle Boucher;Dermot Mallon;Eva Ellinghaus

  335
  Citations

• Wnt signaling regulates mitochondrial physiology and insulin sensitivity

  John C. Yoon;Aylwin Ng;Brian H. Kim;Antonio Bianco

  264
  Citations

• A genome-wide siRNA screen reveals multiple mTORC1 independent signaling pathways regulating autophagy under normal nutritional conditions

  Marta M. Lipinski;Greg Hoffman;Aylwin Ng;Wen Zhou

  244
  Citations

• Identification of Atg5-dependent transcriptional changes and increases in mitochondrial mass in Atg5-deficient T lymphocytes.

  Linda M. Stephenson;Brian C. Miller;Aylwin Ng;Jason Eisenberg

  233
  Citations

• Ubiquitin accumulation in autophagy-deficient mice is dependent on the Nrf2-mediated stress response pathway: a potential role for protein aggregation in autophagic substrate selection

  Brigit E. Riley;Stephen E. Kaiser;Thomas A. Shaler;Aylwin C.Y. Ng;Aylwin C.Y. Ng

  230
  Citations

• Leucine-rich repeat (LRR) proteins: integrators of pattern recognition and signaling in immunity.

  Aylwin Ng;Ramnik J Xavier

  222
  Citations