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D-Index & Metrics

Genetics

D-Index
93
Citations
63646
World Ranking
948
National Ranking
135

Overview

Sarah Edkins is affiliated with Cardiff University in the United Kingdom and has contributed to research primarily in the fields of Medicine and Biochemistry, Genetics and Molecular Biology. Their work spans a range of topics including sepsis diagnosis and treatment, genetic associations and epidemiology, bioinformatics and genomic networks, nutrition, genetics and disease, acute myeloid leukemia research, epigenetics and DNA methylation, as well as cancer cells and metastasis.

Their recent published papers include the following:

  • Zeb1 modulates hematopoietic stem cell fates required for suppressing acute myeloid leukemia, 2020, Journal of Clinical Investigation
  • Distinctive Features of Orbital Adipose Tissue (OAT) in Graves' Orbitopathy, 2020, International Journal of Molecular Sciences
  • Common variants at the MHC locus and at chromosome 16q24.1 predispose to Barrett's esophagus, 2020, UNC Libraries
  • nSeP: immune and metabolic biomarkers for early detection of neonatal sepsis-protocol for a prospective multicohort study, 2021, BMJ Open
  • Gene filtering strategies for machine learning guided biomarker discovery using neonatal sepsis RNA-seq data, 2023, Frontiers in Genetics

Their collaborative network includes frequent coauthors such as Robert Andrews, James E. McLaren, Peter Ghazal, William J. Watkins, and Edward Parkinson.

Sarah Edkins's research is often published in academic venues including UNC Libraries, BMJ Open, Journal of Clinical Investigation, International Journal of Molecular Sciences, and Frontiers in Genetics.

The main areas of study reflected in their work include Medicine as well as Biochemistry, Genetics and Molecular Biology. Within these broader fields, subfields of focus encompass Molecular Biology, Genetics, Epidemiology, Immunology, and Surgery.

Key topics covered by their research are:

  • Sepsis Diagnosis and Treatment
  • Genetic Associations and Epidemiology
  • Bioinformatics and Genomic Networks
  • Nutrition, Genetics, and Disease
  • Acute Myeloid Leukemia Research
  • Epigenetics and DNA Methylation
  • Cancer Cells and Metastasis

Best Publications

  • Mutations of the BRAF gene in human cancer

    Helen Davies;Graham R. Bignell;Charles Cox;Philip Stephens

  • Patterns of somatic mutation in human cancer genomes

    Christopher Greenman;Philip Stephens;Raffaella Smith;Gillian L. Dalgliesh

  • Genetic risk and a primary role for cell-mediated immune mechanisms in multiple sclerosis

    Stephen Sawcer;Garrett Hellenthal;Matti Pirinen;Chris C. A. Spencer

  • Large-scale association analysis provides insights into the genetic architecture and pathophysiology of type 2 diabetes

    Andrew P Morris;Benjamin F Voight;Benjamin F Voight;Tanya M Teslovich;Teresa Ferreira

  • A comprehensive catalogue of somatic mutations from a human cancer genome

    Erin D. Pleasance;R. Keira Cheetham;Philip J. Stephens;David J. Mcbride

  • Genome-wide association analysis identifies 13 new risk loci for schizophrenia

    Stephan Ripke;Stephan Ripke;Colm T. O'Dushlaine;Kimberly D. Chambert;Jennifer L. Moran

  • Systematic sequencing of renal carcinoma reveals inactivation of histone modifying genes

    Gillian L. Dalgliesh;Kyle Furge;Chris Greenman;Lina Chen

  • A small-cell lung cancer genome with complex signatures of tobacco exposure

    Erin D. Pleasance;Philip J. Stephens;Sarah O’Meara;Sarah O’Meara;David J. McBride

  • Identification of 15 new psoriasis susceptibility loci highlights the role of innate immunity

    Lam C. Tsoi;Sarah L. Spain;Sarah L. Spain;Jo Knight;Eva Ellinghaus;Eva Ellinghaus

  • A Genome-Wide Association Study Identifies New Psoriasis Susceptibility Loci and an Interaction Between HLA-C and ERAP1

    Amy Strange;Francesca Capon;Chris C A Spencer

  • Interaction between ERAP1 and HLA-B27 in ankylosing spondylitis implicates peptide handling in the mechanism for HLA-B27 in disease susceptibility

    D M Evans;Spencer Cca.;J J Pointon;Z Su

  • Dense genotyping identifies and localizes multiple common and rare variant association signals in celiac disease

    Gosia Trynka;Karen A Hunt;Nicholas A Bockett;Jihane Romanos

  • Genome-wide trans-ancestry meta-analysis provides insight into the genetic architecture of type 2 diabetes susceptibility.

    Anubha Mahajan;Min Jin Go;Weihua Zhang;Jennifer E. Below

  • Complex landscapes of somatic rearrangement in human breast cancer genomes.

    Philip J. Stephens;David J. Mcbride;Meng-lay Lin;Ignacio Varela

  • Identification of somatically acquired rearrangements in cancer using genome-wide massively parallel paired-end sequencing

    Peter J Campbell;Philip J Stephens;Erin D Pleasance;Sarah O'Meara

  • Genome-wide association study of CNVs in 16,000 cases of eight common diseases and 3,000 shared controls

    Nick Craddock;Matthew E. Hurles;Niall Cardin;Richard D. Pearson

  • Somatic mutations of the histone H3K27 demethylase gene UTX in human cancer

    Gijs Van Haaften;Gillian L Dalgliesh;Helen Davies;Lina Chen

  • The UK10K project identifies rare variants in health and disease

    Klaudia Walter;Josine L. Min;Jie Huang;Lucy Crooks

  • A genome-wide asociation study identifies new psoriasis susceptibility loci and an interaction betwEn HLA-C and ERAP1

    A. Strange;F. Capon;C. C. A. Spencer;J. Knight

  • Genome-wide trans-ancestry meta-analysis provides insight into the genetic architecture of type 2 diabetes susceptibility

    Anubha Mahajan;Min Jin Go;Weihua Zhang;Jennifer E. Below

Frequent Co-Authors

Michael R. Stratton
Michael R. Stratton Wellcome Sanger Institute
Panos Deloukas
Panos Deloukas Queen Mary University of London
Colin N. A. Palmer
Colin N. A. Palmer University of Dundee
Inês Barroso
Inês Barroso University of Exeter
Sarah Hunt
Sarah Hunt European Bioinformatics Institute
Peter Donnelly
Peter Donnelly University of Oxford
Kari Stefansson
Kari Stefansson deCODE Genetics (Iceland)
Philippe Froguel
Philippe Froguel Imperial College London
Unnur Thorsteinsdottir
Unnur Thorsteinsdottir deCODE Genetics (Iceland)

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