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Genetics
Estonia
2026
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Genetics and Molecular Biology
Estonia
2024

D-Index & Metrics

Genetics

D-Index
172
Citations
162430
World Ranking
65
National Ranking
2

Research.com Recognitions

  • 2026 - Research.com Genetics in Estonia Leader Award
  • 2025 - Research.com Genetics in Estonia Leader Award
  • 2024 - Research.com Genetics in Estonia Leader Award
  • 2024 - Research.com Genetics and Molecular Biology in Estonia Leader Award
  • 2023 - Research.com Genetics in Estonia Leader Award
  • 2023 - Research.com Genetics and Molecular Biology in Estonia Leader Award
  • 2022 - Research.com Genetics and Molecular Biology in Estonia Leader Award

Overview

Tonu Esko is affiliated with the University of Tartu in Estonia, focusing on research primarily within biochemistry, genetics, and molecular biology. Their scientific contributions span a range of topics including genetics, molecular biology, immunology, epidemiology, and cardiology and cardiovascular medicine.

Their research addresses various specialized subjects such as genetic associations and epidemiology, genomics and rare diseases, liver disease diagnosis and treatment, epigenetics and DNA methylation, nutrition, genetics, and disease, RNA modifications and cancer, as well as cancer-related molecular mechanisms.

Notable recent publications authored or coauthored by Tonu Esko include:

  • The mutational constraint spectrum quantified from variation in 141,456 humans, 2020, Nature
  • A genomic mutational constraint map using variation in 76,156 human genomes, 2023, Nature
  • Genome-wide association and Mendelian randomisation analysis provide insights into the pathogenesis of heart failure, 2020, Nature Communications
  • Rare coding variants in ten genes confer substantial risk for schizophrenia, 2022, Nature
  • Genomic and drug target evaluation of 90 cardiovascular proteins in 30,931 individuals, 2020, Nature Metabolism

Frequent collaborators in their work include Reedik Mägi, Lili Milani, Andres Metspalu, Erik Abner, and Mari Nelis.

Regular publication venues for Tonu Esko's research are:

  • bioRxiv (Cold Spring Harbor Laboratory)
  • UNC Libraries
  • Nature Communications
  • Nature
  • Nature Genetics

Best Publications

  • Biological insights from 108 schizophrenia-associated genetic loci

    Stephan Ripke;Stephan Ripke;Benjamin M. Neale;Benjamin M. Neale;Aiden Corvin;James T. R. Walters

  • The Genotype-Tissue Expression (GTEx) pilot analysis: Multitissue gene regulation in humans

    Kristin G. Ardlie;David S. Deluca;Ayellet V. Segrè

  • Genetic studies of body mass index yield new insights for obesity biology

    Unknown

  • Association analyses of 249,796 individuals reveal 18 new loci associated with body mass index

    Elizabeth K. Speliotes;Elizabeth K. Speliotes;Cristen J. Willer;Sonja I. Berndt;Keri L. Monda

  • Mapping genomic loci implicates genes and synaptic biology in schizophrenia

    Unknown

  • Discovery and refinement of loci associated with lipid levels

    Cristen J. Willer;Ellen M. Schmidt;Sebanti Sengupta;Gina M. Peloso;Gina M. Peloso;Gina M. Peloso

  • Genome-wide association analyses identify 44 risk variants and refine the genetic architecture of major depression

    Naomi R. Wray;Stephan Ripke;Stephan Ripke;Stephan Ripke;Manuel Mattheisen;MacIej Trzaskowski

  • Gene discovery and polygenic prediction from a genome-wide association study of educational attainment in 1.1 million individuals

    James J. Lee;Robbee Wedow;Aysu Okbay;Edward Kong

  • Genetics of rheumatoid arthritis contributes to biology and drug discovery

    Yukinori Okada;Yukinori Okada;Di Wu;Di Wu;Di Wu;Gosia Trynka;Gosia Trynka;Towfique Raj;Towfique Raj

  • Association studies of up to 1.2 million individuals yield new insights into the genetic etiology of tobacco and alcohol use

    Unknown

  • FinnGen provides genetic insights from a well-phenotyped isolated population

    Unknown

  • A comprehensive 1000 Genomes–based genome-wide association meta-analysis of coronary artery disease

    M Nikpay;A Goel;Won H-H.;L M Hall

  • Hundreds of variants clustered in genomic loci and biological pathways affect human height

    Hana Lango Allen;Karol Estrada;Guillaume Lettre;Sonja I. Berndt

  • Defining the role of common variation in the genomic and biological architecture of adult human height

    Andrew R. Wood;Tonu Esko;Jian Yang;Sailaja Vedantam

  • Large-scale association analysis provides insights into the genetic architecture and pathophysiology of type 2 diabetes

    Andrew P Morris;Benjamin F Voight;Benjamin F Voight;Tanya M Teslovich;Teresa Ferreira

  • Systematic identification of trans eQTLs as putative drivers of known disease associations

    Harm-Jan Westra;Marjolein J Peters;Tõnu Esko;Hanieh Yaghootkar

  • New genetic loci link adipose and insulin biology to body fat distribution

    Unknown

  • Large-scale association analysis identifies new risk loci for coronary artery disease

    Panos Deloukas;Stavroula Kanoni;Christina Willenborg;Martin Farrall

  • Genome-wide association study identifies 30 loci associated with bipolar disorder

    Eli A. Stahl;Eli A. Stahl;Gerome Breen;Andreas J. Forstner;Andrew McQuillin

  • Genome-wide association study identifies 74 loci associated with educational attainment

    Aysu Okbay;Jonathan P. Beauchamp;Mark Alan Fontana;James J. Lee

Frequent Co-Authors

Andres Metspalu
Andres Metspalu University of Tartu
Markus Perola
Markus Perola Finnish Institute for Health and Welfare
André G. Uitterlinden
André G. Uitterlinden Erasmus University Rotterdam
Reedik Mägi
Reedik Mägi University of Tartu
Kari Stefansson
Kari Stefansson deCODE Genetics (Iceland)
Albert Hofman
Albert Hofman Harvard University
Olli T. Raitakari
Olli T. Raitakari Turku University Hospital
Aarno Palotie
Aarno Palotie University of Helsinki
Caroline Hayward
Caroline Hayward University of Edinburgh
Daniel I. Chasman
Daniel I. Chasman Brigham and Women's Hospital

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