World's Best Scientists 2026 revealed!
Andres Metspalu

Andres Metspalu

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Best Scientists
2025
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Genetics
Estonia
2026

D-Index & Metrics

Best Scientists

D-Index
191
Citations
187126
World Ranking
396
National Ranking
2

Genetics

D-Index
188
Citations
177453
World Ranking
37
National Ranking
1

Research.com Recognitions

  • 2026 - Research.com Genetics in Estonia Leader Award
  • 2025 - Research.com Best Scientists Award
  • 2025 - Research.com Genetics in Estonia Leader Award
  • 2024 - Research.com Genetics in Estonia Leader Award
  • 2024 - Research.com Genetics and Molecular Biology in Estonia Leader Award
  • 2023 - Research.com Genetics in Estonia Leader Award
  • 2023 - Research.com Genetics and Molecular Biology in Estonia Leader Award
  • 2022 - Research.com Genetics and Molecular Biology in Estonia Leader Award

Overview

Andres Metspalu is affiliated with the University of Tartu in Estonia. Their research spans across multiple areas within the fields of biochemistry, genetics, and molecular biology, as well as medicine. They have a strong focus on genetics, having published extensively in this subfield along with molecular biology, immunology, physiology, and cardiology and cardiovascular medicine.

The scientist's work covers a range of topics, including:

  • Genetic Associations and Epidemiology
  • Genomics and Rare Diseases
  • Epigenetics and DNA Methylation
  • BRCA Gene Mutations in Cancer
  • Metabolomics and Mass Spectrometry Studies
  • T-cell and B-cell Immunology
  • Genetic and Phenotypic Traits in Livestock

Recent publications demonstrate their involvement in high-impact research. Notable papers include:

  • "Genetics of circulating inflammatory proteins identifies drivers of immune-mediated disease risk and therapeutic targets," 2023, Nature Immunology
  • "Global Effect of Modifiable Risk Factors on Cardiovascular Disease and Mortality," 2023, New England Journal of Medicine
  • "Genomic and phenotypic insights from an atlas of genetic effects on DNA methylation," 2021, Nature Genetics
  • "Personalized early detection and prevention of breast cancer: ENVISION consensus statement," 2020, Nature Reviews Clinical Oncology
  • "A cross-disorder dosage sensitivity map of the human genome," 2022, Cell

Frequent collaborators include:

  • Tõnu Esko
  • Reedik Mägi
  • Lili Milani
  • Mari Nelis
  • Georgi Hudjashov

The scientist's research has been published repeatedly in specific venues, indicating an ongoing relationship with these journals and platforms:

  • Nature Communications
  • bioRxiv (Cold Spring Harbor Laboratory)
  • UNC Libraries
  • Nature Genetics
  • The American Journal of Human Genetics

Andres Metspalu's academic output reflects a comprehensive engagement with genetics and molecular biology in the context of human health and disease. Their work contributes data and insights relevant to genetic epidemiology, epigenetics, immunology, and cancer genetics, aligning with their multidisciplinary approach to biomedicine and related molecular sciences.

Best Publications

  • Biological insights from 108 schizophrenia-associated genetic loci

    Stephan Ripke;Stephan Ripke;Benjamin M. Neale;Benjamin M. Neale;Aiden Corvin;James T. R. Walters

  • Association analyses of 249,796 individuals reveal 18 new loci associated with body mass index

    Elizabeth K. Speliotes;Elizabeth K. Speliotes;Cristen J. Willer;Sonja I. Berndt;Keri L. Monda

  • Worldwide trends in hypertension prevalence and progress in treatment and control from 1990 to 2019: a pooled analysis of 1201 population-representative studies with 104 million participants

    Bin Zhou;Rodrigo M Carrillo-Larco;Goodarz Danaei;Leanne M Riley

  • Discovery and refinement of loci associated with lipid levels

    Cristen J. Willer;Ellen M. Schmidt;Sebanti Sengupta;Gina M. Peloso;Gina M. Peloso;Gina M. Peloso

  • Genome-wide association analyses identify 44 risk variants and refine the genetic architecture of major depression

    Naomi R. Wray;Stephan Ripke;Stephan Ripke;Stephan Ripke;Manuel Mattheisen;MacIej Trzaskowski

  • Gene discovery and polygenic prediction from a genome-wide association study of educational attainment in 1.1 million individuals

    James J. Lee;Robbee Wedow;Aysu Okbay;Edward Kong

  • Genetics of rheumatoid arthritis contributes to biology and drug discovery

    Yukinori Okada;Yukinori Okada;Di Wu;Di Wu;Di Wu;Gosia Trynka;Gosia Trynka;Towfique Raj;Towfique Raj

  • Worldwide trends in blood pressure from 1975 to 2015: a pooled analysis of 1479 population-based measurement studies with 19·1 million participants

    Bin Zhou;James Bentham;Mariachiara Di Cesare;Honor Bixby

  • A comprehensive 1000 Genomes–based genome-wide association meta-analysis of coronary artery disease

    M Nikpay;A Goel;Won H-H.;L M Hall

  • Hundreds of variants clustered in genomic loci and biological pathways affect human height

    Hana Lango Allen;Karol Estrada;Guillaume Lettre;Sonja I. Berndt

  • Defining the role of common variation in the genomic and biological architecture of adult human height

    Andrew R. Wood;Tonu Esko;Jian Yang;Sailaja Vedantam

  • Large-scale association analysis provides insights into the genetic architecture and pathophysiology of type 2 diabetes

    Andrew P Morris;Benjamin F Voight;Benjamin F Voight;Tanya M Teslovich;Teresa Ferreira

  • Analysis of shared heritability in common disorders of the brain

    Verneri Anttila;Verneri Anttila;Brendan Bulik-Sullivan;Brendan Bulik-Sullivan;Hilary K. Finucane;Raymond K. Walters;Raymond K. Walters

  • Systematic identification of trans eQTLs as putative drivers of known disease associations

    Harm-Jan Westra;Marjolein J Peters;Tõnu Esko;Hanieh Yaghootkar

  • Large-scale association analysis identifies new risk loci for coronary artery disease

    Panos Deloukas;Stavroula Kanoni;Christina Willenborg;Martin Farrall

  • Genetic studies of body mass index yield new insights for obesity biology

    Adam E. Locke;Bratati Kahali;Sonja I. Berndt;Anne E. Justice

  • Fine-mapping type 2 diabetes loci to single-variant resolution using high-density imputation and islet-specific epigenome maps.

    Anubha Mahajan;Daniel Taliun;Matthias Thurner;Neil R. Robertson

  • Genome-wide association study identifies 74 loci associated with educational attainment

    Aysu Okbay;Jonathan P. Beauchamp;Mark Alan Fontana;James J. Lee

  • A comprehensive 1000 Genomes-based genome-wide association meta-analysis of coronary artery disease

    Majid Nikpay;Anuj Goel;Hong-Hee Won;Leanne M. Hall

  • Hundreds of variants clustered in genomic loci and biological pathways affect human height

    H. Lango Allen;K. Estrada;G. Lettre;S. I. Berndt

Frequent Co-Authors

Tonu Esko
Tonu Esko University of Tartu
Markus Perola
Markus Perola Finnish Institute for Health and Welfare
Reedik Mägi
Reedik Mägi University of Tartu
Kari Stefansson
Kari Stefansson deCODE Genetics (Iceland)
André G. Uitterlinden
André G. Uitterlinden Erasmus University Rotterdam
Veikko Salomaa
Veikko Salomaa Finnish Institute for Health and Welfare
Albert Hofman
Albert Hofman Harvard University
Christian Gieger
Christian Gieger Helmholtz Zentrum München
Terho Lehtimäki
Terho Lehtimäki Tampere University
Olli T. Raitakari
Olli T. Raitakari Turku University Hospital

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