What is he best known for?
The fields of study he is best known for:
- Gene
- Internal medicine
- DNA
His primary areas of study are Genetic enhancement, Adeno-associated virus, Vector, Virology and Molecular biology.
His studies deal with areas such as Viral vector, Cystic fibrosis, Cystic fibrosis transmembrane conductance regulator and Pathology as well as Genetic enhancement.
His Adeno-associated virus study contributes to a more complete understanding of Recombinant DNA.
The various areas that he examines in his Vector study include Virus and Immunology.
The Virology study combines topics in areas such as Context, Cell culture, Adenoviridae and DNA virus.
His Molecular biology research is multidisciplinary, incorporating elements of Transgene, Gene expression, Gene, DNA and Expression vector.
His most cited work include:
- Treatment of Leber Congenital Amaurosis Due to RPE65 Mutations by Ocular Subretinal Injection of Adeno-Associated Virus Gene Vector: Short-Term Results of a Phase I Trial (799 citations)
- Human gene therapy for RPE65 isomerase deficiency activates the retinoid cycle of vision but with slow rod kinetics (590 citations)
- Stable in vivo expression of the cystic fibrosis transmembrane conductance regulator with an adeno-associated virus vector. (507 citations)
What are the main themes of his work throughout his whole career to date?
Genetic enhancement, Adeno-associated virus, Virology, Recombinant DNA and Immunology are his primary areas of study.
The study incorporates disciplines such as Transgene, Bioinformatics, Vector, Virus and Transduction in addition to Genetic enhancement.
His Adeno-associated virus study combines topics in areas such as Gene delivery, Recombinant virus, Gene expression, Molecular biology and In vivo.
His Virology research integrates issues from Adenoviridae and Viral vector.
The study incorporates disciplines such as Titer and Alpha in addition to Recombinant DNA.
Many of his studies on Immunology apply to Cystic fibrosis as well.
He most often published in these fields:
- Genetic enhancement (46.61%)
- Adeno-associated virus (33.07%)
- Virology (29.17%)
What were the highlights of his more recent work (between 2017-2021)?
- Genetic enhancement (46.61%)
- Genome editing (3.91%)
- Virology (29.17%)
In recent papers he was focusing on the following fields of study:
His scientific interests lie mostly in Genetic enhancement, Genome editing, Virology, MEDLINE and Adeno-associated virus.
Terence R. Flotte has researched Genetic enhancement in several fields, including Harassment, Pediatrics and Bioinformatics.
The Virology study combines topics in areas such as Recombinant DNA and DNA vaccination.
His Recombinant DNA research includes elements of Newborn screening, Virus, Plasmid and Regulatory Pathway.
His work carried out in the field of Adeno-associated virus brings together such families of science as Severe toxicity, Serotype, Immune system, Immunity and Transduction.
His biological study spans a wide range of topics, including Molecular biology and Therapy Trial.
Between 2017 and 2021, his most popular works were:
- Recombinant Adeno-Associated Virus Gene Therapy in Light of Luxturna (and Zolgensma and Glybera): Where Are We, and How Did We Get Here? (54 citations)
- Editing out five Serpina1 paralogs to create a mouse model of genetic emphysema (33 citations)
- Moving Forward After Two Deaths in a Gene Therapy Trial of Myotubular Myopathy (31 citations)
In his most recent research, the most cited papers focused on:
- Gene
- Internal medicine
- DNA
Terence R. Flotte mostly deals with Genetic enhancement, Adeno-associated virus, Genome editing, Virus and Virology.
His Genetic enhancement research includes themes of Transgene and Bioinformatics.
His study ties his expertise on Immunity together with the subject of Adeno-associated virus.
The various areas that Terence R. Flotte examines in his Genome editing study include Computational biology and Cas9.
His research investigates the link between Virus and topics such as Recombinant DNA that cross with problems in Muscle tissue.
His studies deal with areas such as Severe toxicity and Transduction as well as Virology.
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