World's Best Scientists 2026 revealed!

D-Index & Metrics

Biology and Biochemistry

D-Index
78
Citations
27312
World Ranking
4475
National Ranking
2176

Overview

Xiao Xiao is affiliated with the University of North Carolina at Chapel Hill in the United States. Their research focuses primarily on the intersection of biochemistry, genetics, and molecular biology, with a notable emphasis on molecular biology and genetics. Their scholarly contributions extend into specialized subfields including materials chemistry, psychiatry and mental health, and biomedical engineering.

The scientist has explored diverse topics within their work. These include:

  • Genetic Associations and Epidemiology
  • Genetics and Neurodevelopmental Disorders
  • Epigenetics and DNA Methylation
  • Virus-based gene therapy research
  • RNA Research and Splicing
  • Bipolar Disorder and Treatment
  • CRISPR and Genetic Engineering

Their publication record includes papers in a number of venues, with frequent contributions to:

  • UNC Libraries
  • Molecular Psychiatry
  • Schizophrenia Bulletin
  • BMC Medicine
  • Translational Psychiatry

Among the recent papers associated with research in related areas, some are:

  • Conferring Ti-Based MOFs with Defects for Enhanced Sonodynamic Cancer Therapy, 2021, Advanced Materials
  • A Novel Pt-TiO2 Heterostructure with Oxygen-Deficient Layer as Bilaterally Enhanced Sonosensitizer for Synergistic Chemo-Sonodynamic Cancer Therapy, 2020, Advanced Functional Materials
  • A Robust Oxygen-Carrying Hemoglobin-Based Natural Sonosensitizer for Sonodynamic Cancer Therapy, 2021, Nano Letters
  • Solvatochromic Photoluminescent Effects in All-Inorganic Manganese(II)-Based Perovskites by Highly Selective Solvent-Induced Crystal-to-Crystal Phase Transformations, 2020, Angewandte Chemie International Edition
  • Novel Risk Loci Associated With Genetic Risk for Bipolar Disorder Among Han Chinese Individuals, 2020, JAMA Psychiatry

Xiao Xiao has collaborated repeatedly with several coauthors throughout their career. Frequent collaborators include Ming Li, Chuyi Zhang, Yongfeng Yang, Wenqiang Li, and Luxian Lv.

Best Publications

  • Production of High-Titer Recombinant Adeno-Associated Virus Vectors in the Absence of Helper Adenovirus

    Xiao Xiao;Juan Li;Richard Jude Samulski

  • Long-term gene expression and phenotypic correction using adeno-associated virus vectors in the mammalian brain

    Michael G. Kaplitt;Paola Leone;Richard J. Samulski;Xiao Xiao

  • Efficient long-term gene transfer into muscle tissue of immunocompetent mice by adeno-associated virus vector.

    Xiao Xiao;Juan Li;Richard Jude Samulski

  • Cross-Packaging of a Single Adeno-Associated Virus (AAV) Type 2 Vector Genome into Multiple AAV Serotypes Enables Transduction with Broad Specificity

    Joseph E. Rabinowitz;Fabienne Rolling;Chengwen Li;Hervè Conrath

  • Dystrophin Immunity in Duchenne's Muscular Dystrophy

    Jerry R. Mendell;Katherine Campbell;Katherine Campbell;Louise Rodino-Klapac;Louise Rodino-Klapac;Zarife Sahenk;Zarife Sahenk

  • Adeno-associated virus serotype 8 efficiently delivers genes to muscle and heart.

    Zhong Wang;Tong Zhu;Chunping Qiao;Liqiao Zhou

  • Differential and persistent expression patterns of CNS gene transfer by an adeno-associated virus (AAV) vector.

    Thomas J Mccown;Xiao Xiao;Juan Li;George R Breese

  • microRNA-1 and microRNA-206 regulate skeletal muscle satellite cell proliferation and differentiation by repressing Pax7

    Jian Fu Chen;Yazhong Tao;Juan Li;Zhongliang Deng;Zhongliang Deng

  • Adeno-associated virus vector carrying human minidystrophin genes effectively ameliorates muscular dystrophy in mdx mouse model

    Bing Wang;Juan Li;Xiao Xiao

  • Rapid and highly efficient transduction by double-stranded adeno-associated virus vectors in vitro and in vivo.

    Wang Z;Ma Hi;Ma Hi;Li J;Sun L

  • Recombinant viral vector system

    Richard Jude Samulski;Xiao Xiao

  • Historical variations in mutation rate in an epidemic pathogen, Yersinia pestis

    Yujun Cui;Chang Yu;Yanfeng Yan;Dongfang Li

  • Phase 1 Gene Therapy for Duchenne Muscular Dystrophy Using a Translational Optimized AAV Vector

    Dawn E. Bowles;Scott W.J. McPhee;Chengwen Li;Steven James Gray

  • Apolipoprotein B secretion and atherosclerosis are decreased in mice with phospholipid-transfer protein deficiency

    Xian Cheng Jiang;Shucun Qin;Chunping Qiao;Koichi Kawano

  • Effective rescue of dystrophin improves cardiac function in dystrophin-deficient mice by a modified morpholino oligomer

    Bo Wu;Hong M. Moulton;Patrick L. Iversen;Jiangang Jiang

  • Overcoming adeno-associated virus vector size limitation through viral DNA heterodimerization.

    Liangwu Sun;Juan Li;Xiao Xiao

  • Cytochrome P450 2J2 promotes the neoplastic phenotype of carcinoma cells and is up-regulated in human tumors.

    Jian Gang Jiang;Chun Lian Chen;Jeffrey W. Card;Shilin Yang

  • Role for highly regulated rep gene expression in adeno-associated virus vector production.

    Juan Li;Richard Jude Samulski;Xiao Xiao

  • Gene transfer by adeno-associated virus vectors into the central nervous system.

    Xiao Xiao;Juan Li;Thomas J Mccown;Richard J Samulski

  • Direct intramuscular injection with recombinant AAV vectors results in sustained expression in a dog model of hemophilia

    Paul E Monahan;Richard J Samulski;J. Tazelaar;Xiao Xiao

Frequent Co-Authors

Juan Li
Juan Li University of North Carolina at Chapel Hill
Richard J. Samulski
Richard J. Samulski University of North Carolina at Chapel Hill
Dao Wen Wang
Dao Wen Wang Huazhong University of Science and Technology
Darryl C. Zeldin
Darryl C. Zeldin National Institutes of Health
Johnny Huard
Johnny Huard The University of Texas Health Science Center at Houston
Paul D. Robbins
Paul D. Robbins University of Minnesota
Arun Srivastava
Arun Srivastava University of Florida
Nicholas Muzyczka
Nicholas Muzyczka University of Florida
Simon C. Watkins
Simon C. Watkins University of Pittsburgh
Da-Zhi Wang
Da-Zhi Wang Boston Children's Hospital

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