World's Best Scientists 2026 revealed!
Mavis Agbandje-McKenna

Mavis Agbandje-McKenna

D-Index & Metrics

Biology and Biochemistry

D-Index
91
Citations
22963
World Ranking
2370
National Ranking
1262

Overview

Mavis Agbandje-McKenna was affiliated with the University of Florida in the United States. Their research spanned multiple disciplines, focusing primarily on biochemistry, genetics, and molecular biology, with significant contributions in medicine as well. Their work included extensive investigation into genetics, molecular biology, infectious diseases, epidemiology, and cardiology and cardiovascular medicine.

The scientist's main research topics included virus-based gene therapy, CRISPR and genetic engineering, viral gastroenteritis research and epidemiology, viral infections and immunology, CAR-T cell therapy research, RNA interference and gene delivery, and animal virus infection studies.

Their recent papers included:

  • Resolving heterogeneous macromolecular assemblies by Orbitrap-based single-particle charge detection mass spectrometry, 2020, Nature Methods
  • Adeno-associated virus capsid assembly is divergent and stochastic, 2021, Nature Communications
  • Completion of the AAV Structural Atlas: Serotype Capsid Structures Reveals Clade-Specific Features, 2021, Viruses
  • Semirational bioengineering of AAV vectors with increased potency and specificity for systemic gene therapy of muscle disorders, 2022, Science Advances
  • Pre-arrayed Pan-AAV Peptide Display Libraries for Rapid Single-Round Screening, 2020, Molecular Therapy

They frequently published in several venues, including:

  • Journal of Virology
  • UNC Libraries
  • Viruses
  • bioRxiv (Cold Spring Harbor Laboratory)
  • EMPIAR dataset

Frequent collaborators included Mario Mietzsch, Robert McKenna, Paul R. Chipman, Antonette Bennett, and Aravind Asokan.

Best Publications

  • The family Parvoviridae

    Susan F. Cotmore;Mavis Agbandje-McKenna;John A. Chiorini;Dmitry V. Mukha

  • Next generation of adeno-associated virus 2 vectors: point mutations in tyrosines lead to high-efficiency transduction at lower doses.

    Li Zhong;Baozheng Li;Cathryn S. Mah;Lakshmanan Govindasamy

  • Mutational Analysis of the Adeno-Associated Virus Type 2 (AAV2) Capsid Gene and Construction of AAV2 Vectors with Altered Tropism

    Pei Wu;Wu Xiao;Thomas Conlon;Jeffrey Hughes

  • ICTV Virus Taxonomy Profile: Parvoviridae.

    Susan F. Cotmore;Mavis Agbandje-McKenna;Marta Canuti;John A. Chiorini

  • Phase 1 Gene Therapy for Duchenne Muscular Dystrophy Using a Translational Optimized AAV Vector

    Dawn E. Bowles;Scott W.J. McPhee;Chengwen Li;Steven James Gray

  • Identification of Amino Acid Residues in the Capsid Proteins of Adeno-Associated Virus Type 2 That Contribute to Heparan Sulfate Proteoglycan Binding

    Shaun R. Opie;Kenneth H. Warrington;Mavis Agbandje-McKenna;Sergei Zolotukhin

  • α2,3 and α2,6 N-Linked Sialic Acids Facilitate Efficient Binding and Transduction by Adeno-Associated Virus Types 1 and 6

    Zhijian Wu;Edward Miller;Mavis Agbandje-McKenna;Richard Jude Samulski

  • Functional implications of the structure of the murine parvovirus, minute virus of mice

    Mavis Agbandje-McKenna;Antonio L Llamas-Saiz;Feng Wang;Peter Tattersall

  • Structure of Adeno-Associated Virus Serotype 8, a Gene Therapy Vector

    Hyun Joo Nam;Michael Douglas Lane;Eric Padron;Brittney Gurda

  • Tyrosine-phosphorylation of AAV2 vectors and its consequences on viral intracellular trafficking and transgene expression

    Li Zhong;Baozheng Li;Giridhararao Jayandharan;Cathryn S. Mah

  • Novel Properties of Tyrosine-mutant AAV2 Vectors in the Mouse Retina

    Hilda Petrs-Silva;Astra Dinculescu;Qiuhong Li;Wen-Tao Deng

  • Engineering and Selection of Shuffled AAV Genomes: A New Strategy for Producing Targeted Biological Nanoparticles

    Wuping Li;Aravind Asokan;Zhijian Wu;Terry Van Dyke

  • Reengineering a receptor footprint of adeno-associated virus enables selective and systemic gene transfer to muscle

    Aravind Asokan;Julia C. Conway;Jana L. Phillips;Chengwen Li

  • A myocardium tropic adeno-associated virus (AAV) evolved by DNA shuffling and in vivo selection

    Lin Yang;Jiangang Jiang;Lauren M. Drouin;Mavis Agbandje-Mckenna

  • Single Amino Acid Changes Can Influence Titer, Heparin Binding, and Tissue Tropism in Different Adeno-Associated Virus Serotypes

    Zhijian Wu;Aravind Asokan;Joshua C. Grieger;Lakshmanan Govindasamy

  • Engineering liver-detargeted AAV9 vectors for cardiac and musculoskeletal gene transfer.

    Nagesh Pulicherla;Shen Shen;Swati Yadav;Kari Debbink

  • Structure of the Maize streak virus geminate particle.

    Wei Zhang;Norman H Olson;Timothy S Baker;Lee Faulkner;Lee Faulkner

  • Adeno-Associated Virus Type 2 Contains an Integrin α5β1 Binding Domain Essential for Viral Cell Entry

    Aravind Asokan;Julie B. Hamra;Lakshmanan Govindasamy;Mavis Agbandje-McKenna

  • AAV capsid structure and cell interactions.

    Mavis Agbandje-McKenna;Jürgen Kleinschmidt

  • 107. α2, 3 and α2,6 N-Linked Sialic Acid Facilitate Efficient Binding and Transduction by Adeno-Associated Virus Type 1 and 6

    Zhijian Wu;R. Jude Samulski

Frequent Co-Authors

Robert McKenna
Robert McKenna University of Florida
Arun Srivastava
Arun Srivastava University of Florida
Sergei Zolotukhin
Sergei Zolotukhin University of Florida
Nicholas Muzyczka
Nicholas Muzyczka University of Florida
Paul R. Chipman
Paul R. Chipman University of Florida
Timothy S. Baker
Timothy S. Baker University of California, San Diego
John A. Chiorini
John A. Chiorini National Institutes of Health
David N. Silverman
David N. Silverman University of Florida
Aravind Asokan
Aravind Asokan Duke University
Chingkuang Tu
Chingkuang Tu University of Florida

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