World's Best Scientists 2026 revealed!

D-Index & Metrics

Biology and Biochemistry

D-Index
64
Citations
15925
World Ranking
9592
National Ranking
4234

Overview

Sergei Zolotukhin is affiliated with the University of Florida in the United States and has a research focus primarily within Biochemistry, Genetics and Molecular Biology. Their work spans several specialized aspects of molecular biology and genetics, emphasizing applications in virus-based gene therapy research and genetic engineering techniques.

The main fields of study for this scientist include Molecular Biology and Genetics, with additional interests in Nutrition and Dietetics, Oncology, and Sensory Systems.

Research topics covered by their work are diverse and include:

  • Virus-based gene therapy research
  • CRISPR and Genetic Engineering
  • Viral Infectious Diseases and Gene Expression in Insects
  • RNA Interference and Gene Delivery
  • Biochemical Analysis and Sensing Techniques
  • Olfactory and Sensory Function Studies
  • Regulation of Appetite and Obesity

Among their recent scientific papers are:

  • The CRTC1-MAML2 fusion is the major oncogenic driver in mucoepidermoid carcinoma, 2021, JCI Insight
  • A comprehensive study of a 29-capsid AAV library in a non-human primate central nervous system, 2021, Molecular Therapy
  • AAV capsid design: A Goldilocks challenge, 2022, Trends in Molecular Medicine
  • Applying machine learning to predict viral assembly for adeno-associated virus capsid libraries, 2020, Molecular Therapy - Methods & Clinical Development
  • Engineering and In Vitro Selection of a Novel AAV3B Variant with High Hepatocyte Tropism and Reduced Seroreactivity, 2020, Molecular Therapy - Methods & Clinical Development

The frequent publication venues for Sergei Zolotukhin include:

  • Molecular Therapy
  • Molecular Therapy - Methods & Clinical Development
  • Viruses
  • UNC Libraries
  • JCI Insight

Collaborations are notable in their career, with frequent coauthors being:

  • Oleksandr Kondratov
  • Damien Marsic
  • Terence R. Flotte
  • Cedrick D. Dotson
  • Liudmyla Kondratova

Best Publications

  • Recombinant adeno-associated virus purification using novel methods improves infectious titer and yield

    S Zolotukhin;B J Byrne;E Mason;I Zolotukhin

  • Recombinant AAV viral vectors pseudotyped with viral capsids from serotypes 1, 2, and 5 display differential efficiency and cell tropism after delivery to different regions of the central nervous system.

    Corinna Burger;Oleg S. Gorbatyuk;Margaret J. Velardo;Carmen S. Peden

  • A "humanized" green fluorescent protein cDNA adapted for high-level expression in mammalian cells.

    Sergei Zolotukhin;Mark Potter;William W. Hauswirth;John Guy

  • Next generation of adeno-associated virus 2 vectors: point mutations in tyrosines lead to high-efficiency transduction at lower doses.

    Li Zhong;Baozheng Li;Cathryn S. Mah;Lakshmanan Govindasamy

  • Production and purification of serotype 1, 2, and 5 recombinant adeno-associated viral vectors.

    Sergei Zolotukhin;Mark Potter;Irene Zolotukhin;Yoshihisa Sakai

  • Efficient photoreceptor-targeted gene expression in vivo by recombinant adeno-associated virus

    J G Flannery;S Zolotukhin;M I Vaquero;M M LaVail

  • High-efficiency Transduction of the Mouse Retina by Tyrosine-mutant AAV Serotype Vectors

    Hilda Petrs-Silva;Astra Dinculescu;Qiuhong Li;Seok-Hong Min

  • Identification of Amino Acid Residues in the Capsid Proteins of Adeno-Associated Virus Type 2 That Contribute to Heparan Sulfate Proteoglycan Binding

    Shaun R. Opie;Kenneth H. Warrington;Mavis Agbandje-McKenna;Sergei Zolotukhin

  • Efficient transduction of green fluorescent protein in spinal cord neurons using adeno-associated virus vectors containing cell type-specific promoters

    AL Peel;S Zolotukhin;GW Schrimsher;N Muzyczka

  • Neuron-specific transduction in the rat septohippocampal or nigrostriatal pathway by recombinant adeno-associated virus vectors

    Ronald L. Klein;Edwin M. Meyer;Alyson L. Peel;Sergei Zolotukhin

  • Sustained peripheral expression of transgene adiponectin offsets the development of diet-induced obesity in rats.

    Stanislav Shklyaev;George Aslanidi;Michael Tennant;Victor Prima

  • Humanized green fluorescent protein genes and methods

    Sergei Zolotukhin;Nicholas Muzyczka;William W. Hauswirth

  • Structure of Adeno-Associated Virus Serotype 8, a Gene Therapy Vector

    Hyun Joo Nam;Michael Douglas Lane;Eric Padron;Brittney Gurda

  • Tyrosine-phosphorylation of AAV2 vectors and its consequences on viral intracellular trafficking and transgene expression

    Li Zhong;Baozheng Li;Giridhararao Jayandharan;Cathryn S. Mah

  • Adeno-associated virus type 2 VP2 capsid protein is nonessential and can tolerate large peptide insertions at its N terminus.

    Kenneth H. Warrington;Oleg S. Gorbatyuk;Jeffrey K. Harrison;Shaun R. Opie

  • Structural insight into the unique properties of Adeno-Associated Virus Serotype 9

    Michael A. DiMattia;Hyun Joo Nam;Kim Van Vliet;Matthew Mitchell

  • Regulation of adiponectin and leptin gene expression in white and brown adipose tissues: influence of β3-adrenergic agonists, retinoic acid, leptin and fasting

    Yi Zhang;Michael Matheny;Michael Matheny;Sergei Zolotukhin;Nihal Tumer;Nihal Tumer

  • Production and purification of recombinant adeno-associated virus

    William W. Hauswirth;Alfred S. Lewin;Sergei Zolotukhin;Nicholas Muzyczka

  • A dual role of EGFR protein tyrosine kinase signaling in ubiquitination of AAV2 capsids and viral second-strand DNA synthesis.

    Li Zhong;Weihong Zhao;Weihong Zhao;Jianqing Wu;Jianqing Wu;Baozheng Li

  • High-titer recombinant adeno-associated virus production utilizing a recombinant herpes simplex virus type I vector expressing AAV-2 rep and cap

    J E Conway;Cmj ap Rhys;I Zolotukhin;S Zolotukhin

Frequent Co-Authors

Nicholas Muzyczka
Nicholas Muzyczka University of Florida
Mavis Agbandje-McKenna
Mavis Agbandje-McKenna University of Florida
Arun Srivastava
Arun Srivastava University of Florida
Barry J. Byrne
Barry J. Byrne University of Florida
Philip J. Scarpace
Philip J. Scarpace University of Florida
William W. Hauswirth
William W. Hauswirth University of Florida
Herbert Herzog
Herbert Herzog Garvan Institute of Medical Research
Robert McKenna
Robert McKenna University of Florida
Roland W. Herzog
Roland W. Herzog Indiana University
Yi Zhang
Yi Zhang Xidian University

If you think any of the details on this page are incorrect, let us know.

Report an issue

We appreciate your kind effort to assist us to improve this page, it would be helpful providing us with as much detail as possible in the text box below:

Related Online Degrees & Career Pathways

A background in Biology or Biochemistry opens the door to a wide range of online degrees and growing career fields. For those interested in the administrative side of healthcare, you can explore the medical billing and coding job outlook for information on employment trends and professional opportunities.

Affordable and flexible education is more accessible than ever. Individuals can earn credentials like the affordable online him programs or pursue a master degree in nutrition online. These programs prepare graduates for dynamic roles in management, nutrition counseling, and healthcare data analysis.

For those drawn to diagnostic technology, accredited online sonography programs are available, often combining online coursework with clinical experience. Whether you want to work hands-on with patients or specialize in health information systems, online programs offer a range of flexible career pathways connected to the fields of biology and biochemistry.

Best Scientists Citing Sergei Zolotukhin

Trending Scientists