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Molecular Biology

D-Index
71
Citations
17223
World Ranking
1380
National Ranking
701

Overview

Arun Srivastava is affiliated with the University of Florida in the United States and specializes in research within the fields of Biochemistry, Genetics, and Molecular Biology, with a significant focus on Medicine. Their research portfolio comprises a total of 59 publications in biochemistry, genetics, and molecular biology, alongside 27 publications related to medicine.

Their primary areas of study include Molecular Biology and Genetics, with 30 and 29 publications respectively. Srivastava's work extends into various subfields such as Oncology, Cardiology and Cardiovascular Medicine, and Epidemiology. Key research topics central to their work cover virus-based gene therapy research, CRISPR and genetic engineering, CAR-T cell therapy research, RNA interference and gene delivery, viral infections and immunology research, viral infectious diseases and gene expression in insects, and herpesvirus infections and treatments.

Significant recurring publication venues for Srivastava include Human Gene Therapy with 10 papers, followed by Molecular Therapy - Methods & Clinical Development and Molecular Therapy with 4 publications each. The venue Molecular Therapy - Nucleic Acids has hosted 3 of Srivastava's works, while Gene Therapy accounts for 3 papers.

Recent notable papers authored or co-authored by Arun Srivastava include:

  • "Rationale and strategies for the development of safe and effective optimized AAV vectors for human gene therapy" (2023) published in Molecular Therapy - Nucleic Acids
  • "AAV Vectors: Are They Safe?" (2020) published in Human Gene Therapy
  • "Enhanced Transduction of Human Hematopoietic Stem Cells by AAV6 Vectors: Implications in Gene Therapy and Genome Editing" (2020) published in Molecular Therapy - Nucleic Acids
  • "Development of a Clinical Candidate AAV3 Vector for Gene Therapy of Hemophilia B" (2020) published in Human Gene Therapy
  • "Site-Directed Mutagenesis Improves the Transduction Efficiency of Capsid Library-Derived Recombinant AAV Vectors" (2020) published in Molecular Therapy - Methods & Clinical Development

Srivastava frequently collaborates with several researchers, including Keyun Qing, Barry J. Byrne, Roland W. Herzog, Alok Srivastava, and Sanford L. Boye. These collaborations reflect ongoing partnerships within the gene therapy and molecular medicine communities.

Best Publications

  • Nucleotide sequence and organization of the adeno-associated virus 2 genome.

    A Srivastava;E W Lusby;K I Berns

  • Human fibroblast growth factor receptor 1 is a co-receptor for infection by adeno-associated virus 2

    Arun Srivastava;Keyun Qing;Cathryn Mah;Jonathan Hansen

  • Next generation of adeno-associated virus 2 vectors: point mutations in tyrosines lead to high-efficiency transduction at lower doses.

    Li Zhong;Baozheng Li;Cathryn S. Mah;Lakshmanan Govindasamy

  • Impact, Diagnosis and Treatment of von Willebrand Disease*

    J E Sadler;P M Mannucci;Erik Berntorp;N Bochkov

  • High-efficiency Transduction of the Mouse Retina by Tyrosine-mutant AAV Serotype Vectors

    Hilda Petrs-Silva;Astra Dinculescu;Qiuhong Li;Seok-Hong Min

  • The discriminant power of bleeding history for the diagnosis of type 1 von Willebrand disease: an international, multicenter study.

    F Rodeghiero;G Castaman;A Tosetto;J Batlle

  • Rescue of adeno-associated virus from recombinant plasmids: Gene correction within the terminal repeats of AAV

    Richard J. Samulski;Arun Srivastava;Kenneth I. Berns;Nicholas Muzyczka

  • In vivo tissue-tropism of adeno-associated viral vectors.

    Arun Srivastava

  • Adeno-associated virus 2 co-receptors?-first reply

    Keyun Qing;Jonathan Hansen;Arun Srivastava

  • α5β1 integrin as a cellular coreceptor for human parvovirus B19: requirement of functional activation of β1 integrin for viral entry

    Kirsten A. Weigel-Kelley;Mervin C. Yoder;Arun Srivastava

  • Tyrosine-phosphorylation of AAV2 vectors and its consequences on viral intracellular trafficking and transgene expression

    Li Zhong;Baozheng Li;Giridhararao Jayandharan;Cathryn S. Mah

  • Novel Properties of Tyrosine-mutant AAV2 Vectors in the Mouse Retina

    Hilda Petrs-Silva;Astra Dinculescu;Qiuhong Li;Wen-Tao Deng

  • Capsid Modifications for Targeting and Improving the Efficacy of AAV Vectors

    Hildegard Büning;Arun Srivastava

  • Impaired Intracellular Trafficking of Adeno-Associated Virus Type 2 Vectors Limits Efficient Transduction of Murine Fibroblasts

    Jonathan Hansen;Keyun Qing;Hyung Joo Kwon;Cathryn Mah

  • Adeno-Associated Virus Type 2-Mediated Gene Transfer: Altered Endocytic Processing Enhances Transduction Efficiency in Murine Fibroblasts

    Jonathan Hansen;Keyun Qing;Arun Srivastava

  • A dual role of EGFR protein tyrosine kinase signaling in ubiquitination of AAV2 capsids and viral second-strand DNA synthesis.

    Li Zhong;Weihong Zhao;Weihong Zhao;Jianqing Wu;Jianqing Wu;Baozheng Li

  • Adeno-Associated Virus Type 2-Mediated Gene Transfer: Correlation of Tyrosine Phosphorylation of the Cellular Single-Stranded D Sequence-Binding Protein with Transgene Expression in Human Cells In Vitro and Murine Tissues In Vivo

    Keyun Qing;Benjawan Khuntirat;Cathryn Mah;Dagmar M. Kube

  • Parvovirus B19-induced perturbation of human megakaryocytopoiesis in vitro

    A Srivastava;E Bruno;R Briddell;R Cooper

  • Genetic diagnosis of haemophilia and other inherited bleeding disorders.

    Flora Peyvandi;G. Jayandharan;M. Chandy;A. Srivastava

  • Role of tyrosine phosphorylation of a cellular protein in adeno-associated virus 2-mediated transgene expression

    Arun Srivastava;Keyun Qing;Xu-Shan Wang;Selvarangan Ponnazhagan

Frequent Co-Authors

Mavis Agbandje-McKenna
Mavis Agbandje-McKenna University of Florida
Mervin C. Yoder
Mervin C. Yoder Indiana University
Sergei Zolotukhin
Sergei Zolotukhin University of Florida
Selvarangan Ponnazhagan
Selvarangan Ponnazhagan University of Alabama at Birmingham
Nicholas Muzyczka
Nicholas Muzyczka University of Florida
Roland W. Herzog
Roland W. Herzog Indiana University
William W. Hauswirth
William W. Hauswirth University of Florida
Alfred S. Lewin
Alfred S. Lewin University of Florida
Xiao Xiao
Xiao Xiao University of North Carolina at Chapel Hill
Kenneth I. Berns
Kenneth I. Berns University of Florida

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