His primary scientific interests are in Molecular biology, Virology, RNA interference, Genetic enhancement and Capsid. The study incorporates disciplines such as Control of chromosome duplication, Transfection, DNA polymerase, In vivo and Cell biology in addition to Molecular biology. His study focuses on the intersection of Virology and fields such as Adeno-associated virus with connections in the field of Serotype, Receptor and Plasma protein binding.
The RNA interference study combines topics in areas such as Gene silencing, Small hairpin RNA, Computational biology and microRNA. In general microRNA study, his work on Small RNA often relates to the realm of PARP inhibitor, thereby connecting several areas of interest. His Capsid research incorporates themes from Recombinant DNA, Transduction and Adeno-Associated Virus Type 2.
Virology, Gene, Computational biology, Molecular biology and Genetics are his primary areas of study. Dirk Grimm interconnects Plasmid, Vector and Transduction in the investigation of issues within Virology. His research in Gene is mostly focused on Gene expression.
His studies in Computational biology integrate themes in fields like Genome editing, Cas9, Genome and CRISPR. His Molecular biology study integrates concerns from other disciplines, such as Gene silencing, Small hairpin RNA and Cell biology. His biological study deals with issues like microRNA, which deal with fields such as Cancer research.
His scientific interests lie mostly in Computational biology, Gene, CRISPR, Cell biology and Adeno-associated virus. His study in Computational biology is interdisciplinary in nature, drawing from both Transcription, Genome, Viral vector and Immune gene. Dirk Grimm applies his multidisciplinary studies on Gene and In patient in his research.
His Cell biology study also includes
The scientist’s investigation covers issues in Gene, Transduction, CRISPR, Cell biology and Cas9. By researching both Gene and Coronavirus, Dirk Grimm produces research that crosses academic boundaries. His Transduction study combines topics in areas such as Adeno-associated virus, Virus, Capsid, SOX2 and Vectors in gene therapy.
His research investigates the connection with Adeno-associated virus and areas like Genetic enhancement which intersect with concerns in Vector and Enhancer. His Virus research is under the purview of Virology. Dirk Grimm has included themes like Plasmid and Chimeric gene in his Virology study.
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Integrated genomic analyses of ovarian carcinoma
D. Bell;A. Berchuck;M. Birrer;J. Chien.
Fatality in mice due to oversaturation of cellular microRNA/short hairpin RNA pathways.
Dirk Grimm;Konrad L. Streetz;Konrad L. Streetz;Catherine L. Jopling;Theresa A. Storm.
Novel tools for production and purification of recombinant adenoassociated virus vectors.
Dirk Grimm;Andrea Kern;Karola Rittner;Jürgen A. Kleinschmidt.
Human Gene Therapy (1998)
In Vitro and In Vivo Gene Therapy Vector Evolution via Multispecies Interbreeding and Retargeting of Adeno-Associated Viruses
Dirk Grimm;Joyce S. Lee;Lora Wang;Tushar Desai.
Journal of Virology (2008)
Single-Nucleotide Polymorphisms in Soybean
Y. L. Zhu;Y. L. Zhu;Q. J. Song;Q. J. Song;D. L. Hyten;C. P. Van Tassell.
The 37/67-Kilodalton Laminin Receptor Is a Receptor for Adeno-Associated Virus Serotypes 8, 2, 3, and 9
Bassel Akache;Dirk Grimm;Kusum Pandey;Stephen R. Yant.
Journal of Virology (2006)
Fate tracing of mature hepatocytes in mouse liver homeostasis and regeneration.
Yann Malato;Syed Naqvi;Nina Schürmann;Raymond Ng.
Journal of Clinical Investigation (2011)
From virus evolution to vector revolution: use of naturally occurring serotypes of adeno-associated virus (AAV) as novel vectors for human gene therapy
D. Grimm;M. A. Kay.
Current Gene Therapy (2003)
Helper virus-free, optically controllable, and two-plasmid-based production of adeno-associated virus vectors of serotypes 1 to 6
Dirk Grimm;Mark A Kay;Juergen A Kleinschmidt.
Molecular Therapy (2003)
DNA helicase‐mediated packaging of adeno‐associated virus type 2 genomes into preformed capsids
Jason A. King;Ralf Dubielzig;Dirk Grimm;Jürgen A. Kleinschmidt.
The EMBO Journal (2001)
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