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Medicine

D-Index
87
Citations
35326
World Ranking
13474
National Ranking
6850

Overview

Ronny Drapkin is affiliated with the University of Pennsylvania in the United States. Their research spans multiple interconnected fields, primarily focusing on biochemistry, genetics, molecular biology, and medicine. Drapkin's work delves deeply into molecular biology and its applications in oncology and reproductive medicine.

The scientist has contributed extensively to several topics within cancer research and therapy, concentrating on areas such as:

  • Ovarian cancer diagnosis and treatment
  • Cancer, stress, anesthesia, and immune response
  • RNA modifications and cancer
  • PARP inhibition in cancer therapy
  • Chromatin remodeling and cancer
  • Cancer mechanisms and therapy
  • Cancer-related molecular mechanisms research

Some of the recent publications by Ronny Drapkin include:

  • "Nociceptor neurons affect cancer immunosurveillance," 2022, published in Nature
  • "Tumor innervation: peripheral nerves take control of the tumor microenvironment," 2021, published in Journal of Clinical Investigation
  • "Targeting glutamine dependence through GLS1 inhibition suppresses ARID1A-inactivated clear cell ovarian carcinoma," 2021, published in Nature Cancer
  • "Combination ATR and PARP Inhibitor (CAPRI): A phase 2 study of ceralasertib plus olaparib in patients with recurrent, platinum-resistant epithelial ovarian cancer," 2021, published in Gynecologic Oncology
  • "Tumor Innervation: Cancer Has Some Nerve," 2020, published in Trends in cancer

Drapkin frequently publishes in prominent venues, including:

  • Cancer Research
  • bioRxiv (Cold Spring Harbor Laboratory)
  • Clinical Cancer Research
  • Gynecologic Oncology
  • Faculty Opinions - Post-Publication Peer Review of the Biomedical Literature

Collaboration is a significant aspect of Drapkin's research activities. Frequent co-authors include:

  • Euihye Jung
  • Matthew Knarr
  • Hunter D. Reavis
  • Paola D. Vermeer
  • Fiona Simpkins

Through their body of work, Drapkin contributes to a nuanced understanding of cancer biology at the molecular level, combining insights from genetics, immunology, and therapeutic strategies. Their research demonstrates a multidisciplinary approach to cancer treatment development and underlying molecular mechanisms.

Best Publications

  • Pan-cancer analysis of whole genomes

    Peter J. Campbell;Gad Getz;Jan O. Korbel;Joshua M. Stuart

  • Dicer-deficient mouse embryonic stem cells are defective in differentiation and centromeric silencing

    Chryssa Kanellopoulou;Stefan A. Muljo;Andrew L. Kung;Shridar Ganesan

  • Rethinking ovarian cancer: recommendations for improving outcomes

    Sebastian Vaughan;Jermaine I. Coward;Robert C. Bast;Andy Berchuck

  • Whole-genome characterization of chemoresistant ovarian cancer

    Ann-Marie Patch;Ann-Marie Patch;Elizabeth Christie;Dariush Etemadmoghadam;Dariush Etemadmoghadam;Dale W. Garsed

  • Rethinking ovarian cancer II: Reducing mortality from high-grade serous ovarian cancer

    David D. Bowtell;David D. Bowtell;Steffen Böhm;Ahmed A. Ahmed;Paul Joseph Aspuria

  • 53BP1 loss rescues BRCA1 deficiency and is associated with triple-negative and BRCA-mutated breast cancers

    Peter Bouwman;Amal Mahmoud Aly;Jose M. Escandell;Mark Pieterse

  • A candidate precursor to serous carcinoma that originates in the distal fallopian tube.

    Y Lee;A Miron;R Drapkin;M R Nucci

  • Patterns of somatic structural variation in human cancer genomes

    Yilong Li;Nicola D Roberts;Jeremiah A Wala;Jeremiah A Wala;Ofer Shapira;Ofer Shapira

  • Human epididymis protein 4 (HE4) is a secreted glycoprotein that is overexpressed by serous and endometrioid ovarian carcinomas.

    Ronny Drapkin;Hans Henning von Horsten;Yafang Lin;Samuel C. Mok

  • High grade serous ovarian carcinomas originate in the fallopian tube

    S. Intidhar Labidi-Galy;S. Intidhar Labidi-Galy;Eniko Papp;Dorothy Hallberg;Noushin Niknafs;Noushin Niknafs

  • Pretreatment Mitochondrial Priming Correlates with Clinical Response to Cytotoxic Chemotherapy

    Triona Ni Chonghaile;Kristopher A. Sarosiek;Thanh Trang Vo;Jeremy A. Ryan

  • Prognostically relevant gene signatures of high-grade serous ovarian carcinoma

    Roel G.W. Verhaak;Pablo Tamayo;Ji Yeon Yang;Diana Hubbard

  • Transformation of the Fallopian Tube Secretory Epithelium Leads to High-Grade Serous Ovarian Cancer in Brca;Tp53;Pten Models

    Ruth Perets;Gregory A. Wyant;Katherine W. Muto;Jonathan G. Bijron

  • The distal fallopian tube: a new model for pelvic serous carcinogenesis.

    Christopher P. Crum;Ronny Drapkin;Alexander Miron;Tan A. Ince

  • A recurrent mutation in PALB2 in Finnish cancer families

    Hannele Erkko;Bing Xia;Jenni Nikkilä;Johanna Schleutker

  • New Insights Into the Pathogenesis of Serous Ovarian Cancer and Its Clinical Impact

    Keren Levanon;Christopher Crum;Ronny Drapkin

  • Systematic investigation of genetic vulnerabilities across cancer cell lines reveals lineage-specific dependencies in ovarian cancer

    Hiu Wing Cheung;Glenn S. Cowley;Barbara A. Weir;Jesse S. Boehm

  • A comprehensive analysis of PAX8 expression in human epithelial tumors.

    Anna R. Laury;Ruth Perets;Huiying Piao;Jeffrey F. Krane

  • Lessons from BRCA: The Tubal Fimbria Emerges as an Origin for Pelvic Serous Cancer

    Christopher P. Crum;Ronny Drapkin;David Kindelberger;Fabiola Medeiros

  • The p400 complex is an essential E1A transformation target.

    Miriam Fuchs;Jill Gerber;Ronny Drapkin;Ronny Drapkin;Said Sif

Frequent Co-Authors

Ursula A. Matulonis
Ursula A. Matulonis Harvard University
Christopher P. Crum
Christopher P. Crum Brigham and Women's Hospital
Gordon B. Mills
Gordon B. Mills Oregon Health & Science University
David D.L. Bowtell
David D.L. Bowtell Peter MacCallum Cancer Centre
David M. Livingston
David M. Livingston Harvard University
Danny Reinberg
Danny Reinberg University of Miami
Beth Y. Karlan
Beth Y. Karlan University of California, Los Angeles
Joan S. Brugge
Joan S. Brugge Harvard University
William C. Hahn
William C. Hahn Dana-Farber Cancer Institute
Adam R. Karpf
Adam R. Karpf University of Nebraska Medical Center

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