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Biology and Biochemistry

D-Index
62
Citations
14039
World Ranking
10780
National Ranking
825

Overview

Jeremy E. Turnbull is affiliated with the University of Liverpool in the United Kingdom. Their research primarily focuses on medicine and biochemistry, genetics, and molecular biology, with significant contributions to infectious diseases, epidemiology, cell biology, molecular biology, and oncology.

The scientist's main research topics include:

  • SARS-CoV-2 and COVID-19 Research
  • Proteoglycans and glycosaminoglycans research
  • Influenza Virus Research Studies
  • COVID-19 Clinical Research Studies
  • Glycosylation and Glycoproteins Research
  • Lung Cancer Research Studies
  • Heparin-Induced Thrombocytopenia and Thrombosis

Jeremy E. Turnbull has contributed to a number of research papers related to the interaction between heparin and SARS-CoV-2 as well as the viral spike protein's receptor binding domain. Select recent publications include:

  • Heparin Inhibits Cellular Invasion by SARS-CoV-2: Structural Dependence of the Interaction of the Spike S1 Receptor-Binding Domain with Heparin (2020), published in Thrombosis and Haemostasis
  • The 2019 coronavirus (SARS-CoV-2) surface protein (Spike) S1 Receptor Binding Domain undergoes conformational change upon heparin binding (2020), published in bioRxiv (Cold Spring Harbor Laboratory)
  • Synthetic Heparan Sulfate Mimetic Pixatimod (PG545) Potently Inhibits SARS-CoV-2 by Disrupting the Spike-ACE2 Interaction (2022), published in ACS Central Science
  • Unfractionated heparin inhibits live wild type SARS-CoV-2 cell infectivity at therapeutically relevant concentrations (2020), published in British Journal of Pharmacology
  • Heparin inhibits cellular invasion by SARS-CoV-2: structural dependence of the interaction of the surface protein (spike) S1 receptor binding domain with heparin (2020), published in bioRxiv (Cold Spring Harbor Laboratory)

Their frequent coauthors include:

  • Edwin A. Yates
  • Mark A. Skidmore
  • Courtney J. Mycroft-West
  • Marcelo A. Lima
  • Scott E. Guimond

Jeremy E. Turnbull has published extensively in venues such as:

  • bioRxiv (Cold Spring Harbor Laboratory)
  • ACS Central Science
  • Frontiers in Pharmacology
  • Cardiovascular Diabetology
  • Thrombosis and Haemostasis

Best Publications

  • EXTRACELLULAR MATRIX AND CELL SIGNALLING: THE DYNAMIC COOPERATION OF INTEGRIN, PROTEOGLYCAN AND GROWTH FACTOR RECEPTOR

    Soo-Hyun Kim;Jeremy E Turnbull;Scott E Guimond

  • Identification of the basic fibroblast growth factor binding sequence in fibroblast heparan sulfate.

    J. E. Turnbull;D. G. Fernig;Youquiang Ke;M. C. Wilkinson

  • Heparan sulfate: decoding a dynamic multifunctional cell regulator.

    Jeremy Turnbull;Andrew Powell;Scott Guimond

  • Examination of the substrate specificity of heparin and heparan sulfate lyases.

    R J Linhardt;Jeremy E Turnbull;H M Wang;D Loganathan

  • Heparan Sulfate Oligosaccharides Require 6-O-Sulfation for Promotion of Basic Fibroblast Growth Factor Mitogenic Activity

    David A. Pye;Romain R. Vives;Jeremy E. Turnbull;Patricia Hyde

  • Interactions of heparin/heparan sulfate with proteins: appraisal of structural factors and experimental approaches.

    Andrew K Powell;Edwin A Yates;David G Fernig;Jeremy E Turnbull

  • Modular synthesis of heparan sulfate oligosaccharides for structure-activity relationship studies.

    Sailaja Arungundram;Kanar Al-Mafraji;Jinkeng Asong;Franklin E. Leach

  • Heparin Inhibits Cellular Invasion by SARS-CoV-2: Structural Dependence of the Interaction of the Spike S1 Receptor-Binding Domain with Heparin.

    Courtney J. Mycroft-West;Dunhao Su;Isabel Pagani;Timothy R. Rudd

  • Cell surface syndecan-1 on distinct cell types differs in fine structure and ligand binding of its heparan sulfate chains.

    M Kato;H Wang;M Bernfield;John T Gallagher

  • Specific heparan sulfate saccharides mediate the activity of basic fibroblast growth factor

    A Walker;Jeremy E Turnbull;John T Gallagher

  • Fibroblast growth factor receptor signalling is dictated by specific heparan sulphate saccharides

    Scott E. Guimond;Jeremy E. Turnbull

  • Identification of the heparan sulfate binding sites in the cellular prion protein.

    Richard G. Warner;Christoph Hundt;Stefan Weiss;Jeremy E. Turnbull

  • Structural Modification of Fibroblast Growth Factor-binding Heparan Sulfate at a Determinative Stage of Neural Development

    Yardenah G. Brickman;Miriam D. Ford;John T. Gallagher;Victor Nurcombe

  • Fine structure of heparan sulfate regulates syndecan-1 function and cell behavior

    R D Sanderson;Jeremy E Turnbull;John T Gallagher;A D Lander

  • Heparan sulfate regulates amyloid precursor protein processing by BACE1, the Alzheimer's β-secretase

    Zoe Scholefield;Edwin A. Yates;Gareth Wayne;Augustin Amour

  • Emerging glycomics technologies.

    Jeremy E Turnbull;Robert A Field

  • A strategy for rapid sequencing of heparan sulfate and heparin saccharides

    Jeremy E. Turnbull;John J. Hopwood;John T. Gallagher

  • The 2019 coronavirus (SARS-CoV-2) surface protein (Spike) S1 Receptor Binding Domain undergoes conformational change upon heparin binding

    Courtney J Mycroft-West;Dunhao Su;Stefano Elli;Yong Li

  • Distribution of iduronate 2-sulphate residues in heparan sulphate. Evidence for an ordered polymeric structure.

    Jeremy E Turnbull;John T Gallagher

  • Interactions of Multiple Heparin Binding Growth Factors with Neuropilin-1 and Potentiation of the Activity of Fibroblast Growth Factor-2

    David C. West;Chris G. Rees;Laurence Duchesne;Susannah J. Patey

Frequent Co-Authors

John T. Gallagher
John T. Gallagher University of Manchester
David G. Fernig
David G. Fernig University of Liverpool
Marco Guerrini
Marco Guerrini Istituto G. Ronzoni
Toin H. van Kuppevelt
Toin H. van Kuppevelt Radboud University
Geert-Jan Boons
Geert-Jan Boons University of Georgia
Miles W. Carroll
Miles W. Carroll University of Oxford
Giangiacomo Torri
Giangiacomo Torri Istituto di Ricerche Chimiche e Biochimiche G. Ronzoni
Malcolm Lyon
Malcolm Lyon University of Manchester
Kevin Pagel
Kevin Pagel Freie Universität Berlin
Robert A. Field
Robert A. Field University of Manchester

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