D-Index & Metrics Best Publications

D-Index & Metrics D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines.

Discipline name D-index D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines. Citations Publications World Ranking National Ranking
Biology and Biochemistry D-index 70 Citations 15,658 181 World Ranking 4470 National Ranking 330

Overview

What is he best known for?

The fields of study he is best known for:

  • Enzyme
  • Gene
  • Biochemistry

John T. Gallagher mostly deals with Biochemistry, Heparan sulfate, Sulfation, Cell biology and Proteoglycan. His study in Heparin, Binding site, Disaccharide, Fibroblast growth factor and Receptor is carried out as part of his Biochemistry studies. A large part of his Heparan sulfate studies is devoted to Heparinase.

His Sulfation research integrates issues from Perlecan, SULF1, Structural motif, Extracellular matrix and Sequence analysis. He has researched Cell biology in several fields, including Neurite, Neural cell adhesion molecule and Sensory neuron. The study incorporates disciplines such as Syndecan 1, Growth cone, Chondroitin sulfate and Ectodomain in addition to Proteoglycan.

His most cited work include:

  • Identification of the basic fibroblast growth factor binding sequence in fibroblast heparan sulfate. (449 citations)
  • Structure and function of heparan sulphate proteoglycans (415 citations)
  • Interaction of hepatocyte growth factor with heparan sulfate : elucidation of the major heparan sulfate structural determinants (285 citations)

What are the main themes of his work throughout his whole career to date?

The scientist’s investigation covers issues in Biochemistry, Heparan sulfate, Sulfation, Cell biology and Heparin. His study in Biochemistry focuses on Glycosaminoglycan, Fibroblast growth factor, Proteoglycan, Glucosamine and Binding site. His Fibroblast growth factor study incorporates themes from Basic fibroblast growth factor, Receptor tyrosine kinase and Cell growth.

He combines subjects such as Molecular biology, Growth factor and Enzyme with his study of Heparan sulfate. The concepts of his Sulfation study are interwoven with issues in Embryonic stem cell, Perlecan, Lyase, Polysaccharide and Disaccharide. His study in Cell biology is interdisciplinary in nature, drawing from both Cell and Heparan sulphate.

He most often published in these fields:

  • Biochemistry (68.11%)
  • Heparan sulfate (38.92%)
  • Sulfation (27.57%)

What were the highlights of his more recent work (between 2005-2019)?

  • Biochemistry (68.11%)
  • Heparan sulfate (38.92%)
  • Sulfation (27.57%)

In recent papers he was focusing on the following fields of study:

John T. Gallagher focuses on Biochemistry, Heparan sulfate, Sulfation, Heparin and Fibroblast growth factor. His works in Receptor, Extracellular matrix, Signal transduction, Plasma protein binding and Proteoglycan are all subjects of inquiry into Biochemistry. Heparinase is the focus of his Heparan sulfate research.

His Sulfation research incorporates elements of Glycosaminoglycan, Dermatan sulfate, Glycan, Binding site and Cell biology. His studies in Heparin integrate themes in fields like Cancer research, In vitro and Immunology. John T. Gallagher focuses mostly in the field of Fibroblast growth factor, narrowing it down to topics relating to Extracellular and, in certain cases, Vascular endothelial growth factor.

Between 2005 and 2019, his most popular works were:

  • Proteoglycan-Specific Molecular Switch for RPTPσ Clustering and Neuronal Extension (238 citations)
  • HSulf-2, an extracellular endoglucosamine-6-sulfatase, selectively mobilizes heparin-bound growth factors and chemokines: effects on VEGF, FGF-1, and SDF-1 (177 citations)
  • VEGF165-binding sites within heparan sulfate encompass two highly sulfated domains and can be liberated by K5 lyase (138 citations)

In his most recent research, the most cited papers focused on:

  • Enzyme
  • Gene
  • Biochemistry

His primary scientific interests are in Sulfation, Biochemistry, Heparan sulfate, Fibroblast growth factor and Cell biology. His studies deal with areas such as Glycosidic bond, HEXA, Glycomics and Matrix as well as Sulfation. His study in Biochemistry concentrates on Extracellular matrix, Signal transduction and Receptor.

Heparan sulfate is the subject of his research, which falls under Glycosaminoglycan. His work carried out in the field of Fibroblast growth factor brings together such families of science as SULF1, Growth factor, Cell growth and Heparin. John T. Gallagher studied Cell biology and Chondroitin sulfate that intersect with Proteoglycan, Neurite, Sensory neuron and Ectodomain.

This overview was generated by a machine learning system which analysed the scientist’s body of work. If you have any feedback, you can contact us here.

Best Publications

Structure and function of heparan sulphate proteoglycans

John T Gallagher;Malcolm Lyon;William P Steward.
Biochemical Journal (1986)

661 Citations

Identification of the basic fibroblast growth factor binding sequence in fibroblast heparan sulfate.

J. E. Turnbull;D. G. Fernig;Youquiang Ke;M. C. Wilkinson.
Journal of Biological Chemistry (1992)

613 Citations

Heparan sulfate: growth control with a restricted sequence menu.

John T. Gallagher.
Journal of Clinical Investigation (2001)

432 Citations

Interaction of hepatocyte growth factor with heparan sulfate : elucidation of the major heparan sulfate structural determinants

Malcolm Lyon;Jon A Deakin;K Mizuno;T Nakamura.
Journal of Biological Chemistry (1994)

401 Citations

The extended family of proteoglycans: social residents of the pericellular zone

John T Gallagher.
Current Opinion in Cell Biology (1989)

368 Citations

Examination of the substrate specificity of heparin and heparan sulfate lyases.

R J Linhardt;Jeremy E Turnbull;H M Wang;D Loganathan.
Biochemistry (1990)

363 Citations

The Interaction of the Transforming Growth Factor-βs with Heparin/Heparan Sulfate Is Isoform-specific

Malcolm Lyon;Graham Rushton;John T. Gallagher.
Journal of Biological Chemistry (1997)

357 Citations

Proteoglycan-Specific Molecular Switch for RPTPσ Clustering and Neuronal Extension

Charlotte H. Coles;Yingjie Shen;Alan P. Tenney;Alan P. Tenney;Christian Siebold.
Science (2011)

325 Citations

Heparan Sulfate Oligosaccharides Require 6-O-Sulfation for Promotion of Basic Fibroblast Growth Factor Mitogenic Activity

David A. Pye;Romain R. Vives;Jeremy E. Turnbull;Patricia Hyde.
Journal of Biological Chemistry (1998)

324 Citations

Neuropilin-1 Binds Vascular Endothelial Growth Factor 165, Placenta Growth Factor-2, and Heparin via Its b1b2 Domain

Roni Mamluk;Ze'ev Gechtman;Matthew E Kutcher;Nijole Gasiunas.
Journal of Biological Chemistry (2002)

317 Citations

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