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Hugues Lortat-Jacob

Hugues Lortat-Jacob

Grenoble Alpes University
France

D-Index & Metrics

Biology and Biochemistry

D-Index
66
Citations
12335
World Ranking
8866
National Ranking
313

Hugues Lortat-Jacob publication distribution in Biology and Biochemistry in 2026

The chart shows the distribution of publications by all Research.com ranked scientists in the field of Biology and Biochemistry in 2026. The highlighted bar marks where Hugues Lortat-Jacob sits on this spectrum.

47–56 publications: 8 scientists 57–66 publications: 35 scientists 67–76 publications: 106 scientists 77–86 publications: 231 scientists 87–96 publications: 414 scientists 97–106 publications: 546 scientists 107–116 publications: 704 scientists 117–126 publications: 849 scientists 127–136 publications: 980 scientists 137–146 publications: 942 scientists 147–156 publications: 969 scientists 157–166 publications: 950 scientists 167–176 publications: 951 scientists 177–186 publications: 915 scientists 187–196 publications: 787 scientists 197–206 publications: 841 scientists 207–216 publications: 735 scientists 217–226 publications: 709 scientists 227–236 publications: 651 scientists 237–246 publications: 605 scientists 247–256 publications: 510 scientists 257–266 publications: 524 scientists 267–276 publications: 434 scientists 277–286 publications: 418 scientists 287–296 publications: 350 scientists 297–306 publications: 363 scientists 307–316 publications: 315 scientists 317–326 publications: 296 scientists 327–336 publications: 261 scientists 337–346 publications: 240 scientists 347–356 publications: 219 scientists 357–366 publications: 197 scientists 367–376 publications: 154 scientists 377–386 publications: 161 scientists 387–396 publications: 155 scientists 397–406 publications: 145 scientists 407–416 publications: 124 scientists 417–426 publications: 112 scientists 427–436 publications: 132 scientists 437–446 publications: 116 scientists 447–456 publications: 99 scientists 457–466 publications: 81 scientists 467–476 publications: 91 scientists 477–486 publications: 80 scientists 487–496 publications: 80 scientists 497–506 publications: 60 scientists 507–516 publications: 36 scientists 517–526 publications: 46 scientists 527–536 publications: 54 scientists 537–546 publications: 44 scientists 547–556 publications: 43 scientists 557–566 publications: 43 scientists 567–576 publications: 42 scientists 577–586 publications: 25 scientists 587–596 publications: 34 scientists 597–606 publications: 23 scientists 607–616 publications: 33 scientists 617–626 publications: 31 scientists 627–636 publications: 27 scientists 637–646 publications: 25 scientists 647–656 publications: 28 scientists 657–666 publications: 34 scientists 667–676 publications: 18 scientists 677–686 publications: 16 scientists 687–696 publications: 10 scientists 697–706 publications: 12 scientists 707–716 publications: 21 scientists 717–726 publications: 12 scientists 727–736 publications: 12 scientists 737–746 publications: 10 scientists 747–756 publications: 7 scientists 757–766 publications: 13 scientists 767–776 publications: 15 scientists 777–786 publications: 13 scientists 787–796 publications: 9 scientists 797–806 publications: 9 scientists 807–816 publications: 7 scientists 817–826 publications: 4 scientists 827–836 publications: 9 scientists 837–846 publications: 7 scientists 847–856 publications: 3 scientists 857–866 publications: 5 scientists 867–876 publications: 5 scientists 877–886 publications: 11 scientists 887–896 publications: 3 scientists 897–906 publications: 4 scientists 907–916 publications: 7 scientists 917–926 publications: 5 scientists 927–936 publications: 6 scientists 937–946 publications: 6 scientists 947–956 publications: 3 scientists 957–966 publications: 7 scientists 967–976 publications: 2 scientists 977–986 publications: 2 scientists 987–996 publications: 1 scientists 997–1,006 publications: 5 scientists 1,007–1,016 publications: 2 scientists 1,017–1,026 publications: 2 scientists 1,027 publications: 1 scientists 1,028+ publications: 100 scientists
47 publications 1,028+

This scientist: 182 publications — 42nd percentile

42% of scientists in this discipline score the same or lower.

The last bar groups every scientist with 1,028 publications or more.

Hugues Lortat-Jacob D-index placement in Biology and Biochemistry in 2026

The chart shows the D-index (discipline H-index) distribution of Biology and Biochemistry scientists ranked by Research.com in 2026. The highlighted bar marks where Hugues Lortat-Jacob sits on this spectrum.

40–41 D-Index: 80 scientists 42–43 D-Index: 183 scientists 44–45 D-Index: 317 scientists 46–47 D-Index: 504 scientists 48–49 D-Index: 718 scientists 50–51 D-Index: 900 scientists 52–53 D-Index: 1,026 scientists 54–55 D-Index: 1,150 scientists 56–57 D-Index: 1,236 scientists 58–59 D-Index: 1,253 scientists 60–61 D-Index: 1,163 scientists 62–63 D-Index: 1,131 scientists 64–65 D-Index: 1,032 scientists 66–67 D-Index: 897 scientists 68–69 D-Index: 814 scientists 70–71 D-Index: 715 scientists 72–73 D-Index: 709 scientists 74–75 D-Index: 596 scientists 76–77 D-Index: 512 scientists 78–79 D-Index: 473 scientists 80–81 D-Index: 412 scientists 82–83 D-Index: 373 scientists 84–85 D-Index: 358 scientists 86–87 D-Index: 285 scientists 88–89 D-Index: 273 scientists 90–91 D-Index: 227 scientists 92–93 D-Index: 208 scientists 94–95 D-Index: 193 scientists 96–97 D-Index: 153 scientists 98–99 D-Index: 157 scientists 100–101 D-Index: 148 scientists 102–103 D-Index: 120 scientists 104–105 D-Index: 113 scientists 106–107 D-Index: 100 scientists 108–109 D-Index: 86 scientists 110–111 D-Index: 67 scientists 112–113 D-Index: 72 scientists 114–115 D-Index: 73 scientists 116–117 D-Index: 64 scientists 118–119 D-Index: 53 scientists 120–121 D-Index: 60 scientists 122–123 D-Index: 54 scientists 124–125 D-Index: 43 scientists 126–127 D-Index: 38 scientists 128–129 D-Index: 49 scientists 130–131 D-Index: 26 scientists 132–133 D-Index: 18 scientists 134–135 D-Index: 23 scientists 136–137 D-Index: 32 scientists 138–139 D-Index: 32 scientists 140–141 D-Index: 27 scientists 142–143 D-Index: 19 scientists 144–145 D-Index: 22 scientists 146–147 D-Index: 12 scientists 148–149 D-Index: 16 scientists 150–151 D-Index: 14 scientists 152–153 D-Index: 10 scientists 154–155 D-Index: 13 scientists 156–157 D-Index: 10 scientists 158–159 D-Index: 7 scientists 160–161 D-Index: 9 scientists 162–163 D-Index: 13 scientists 164–165 D-Index: 4 scientists 166 D-Index: 4 scientists 167+ D-Index: 98 scientists
40 D-Index 167+

This scientist: 66 D-Index — 57th percentile

57% of scientists in this discipline score the same or lower.

The last bar groups every scientist with 167 D-Index or more.

Overview

Hugues Lortat-Jacob is affiliated with Grenoble Alpes University in France. Their research primarily spans the fields of Biochemistry, Genetics and Molecular Biology, with 28 publications in this overall area. Within this domain, Lortat-Jacob's work covers Molecular Biology, Cell Biology, Organic Chemistry, Immunology, and Cancer Research.

The primary research topics addressed in their publications include:

  • Proteoglycans and glycosaminoglycans research
  • Glycosylation and Glycoproteins Research
  • Carbohydrate Chemistry and Synthesis
  • Protease and Inhibitor Mechanisms
  • Neurobiology and Insect Physiology Research
  • Invertebrate Immune Response Mechanisms
  • Platelet Disorders and Treatments

Notable recent papers authored include:

  • Heparan Sulfate Proteoglycans Biosynthesis and Post Synthesis Mechanisms Combine Few Enzymes and Few Core Proteins to Generate Extensive Structural and Functional Diversity, 2020, Molecules
  • Structure of the human heparan sulfate polymerase complex EXT1-EXT2, 2022, Nature Communications
  • IFNγ binding to extracellular matrix prevents fatal systemic toxicity, 2023, Nature Immunology
  • Extracellular endosulfatase Sulf-2 harbors a chondroitin/dermatan sulfate chain that modulates its enzyme activity, 2022, Cell Reports
  • Axonal chemokine-like Orion induces astrocyte infiltration and engulfment during mushroom body neuronal remodeling, 2021, Nature Communications

Frequent co-authors in Lortat-Jacob's publications include Evelyne Gout, Rebekka Wild, Romain R. Vivès, Rabia Sadir, and Yoann Crétinon. This collaborative network reflects ongoing partnerships across various projects.

Lortat-Jacob's work has appeared predominantly in the following publication venues:

  • Nature Immunology
  • bioRxiv (Cold Spring Harbor Laboratory)
  • Nature Communications
  • EMPIAR dataset
  • Molecules

Best Publications

  • DC-SIGN and L-SIGN Are High Affinity Binding Receptors for Hepatitis C Virus Glycoprotein E2

    Pierre-Yves Lozach;Hugues Lortat-Jacob;Agnès de Lacroix de Lavalette;Isabelle Staropoli

  • Human Cytomegalovirus Binding to DC-SIGN Is Required for Dendritic Cell Infection and Target Cell trans-Infection

    Franck Halary;Ali Amara;Hugues Lortat-Jacob;Martin Messerle

  • Endocan or endothelial cell specific molecule-1 (ESM-1) : A potential novel endothelial cell marker and a new target for cancer therapy

    Stéphane Sarrazin;E. Adam;M. Lyon;F. Depontieu

  • Selective Interactions of Polyanions with Basic Surfaces on Human Immunodeficiency Virus Type 1 gp120

    Maxime Moulard;Hugues Lortat-Jacob;Isabelle Mondor;Guillaume Roca

  • Stromal cell-derived factor-1alpha associates with heparan sulfates through the first beta-strand of the chemokine.

    Ali Amara;Olivier Lorthioir;Agustin Valenzuela;Aude Magerus

  • Structural diversity of heparan sulfate binding domains in chemokines.

    Hugues Lortat-Jacob;Aurélien Grosdidier;Anne Imberty

  • Sulfated polysaccharides increase plasma levels of SDF-1 in monkeys and mice: involvement in mobilization of stem/progenitor cells

    Elizabeth A. Sweeney;Hugues Lortat-Jacob;Gregory V. Priestley;Betty Nakamoto

  • Heparan sulfate-mediated binding of infectious dengue virus type 2 and yellow fever virus.

    Raphaële Germi;Jean-Marc Crance;Daniel Garin;Josette Guimet

  • Characterization of the stromal cell-derived factor-1alpha-heparin complex.

    Rabia Sadir;Françoise Baleux;Aurélien Grosdidier;Aurélien Grosdidier;Anne Imberty

  • Structural view of glycosaminoglycan-protein interactions.

    Anne Imberty;Hugues Lortat-Jacob;Serge Pérez

  • Heparan Sulfate/Heparin Oligosaccharides Protect Stromal Cell-derived Factor-1 (SDF-1)/CXCL12 against Proteolysis Induced by CD26/Dipeptidyl Peptidase IV *

    Rabia Sadir;Anne Imberty;Françoise Baleux;Hugues Lortat-Jacob

  • Cellular glycosaminoglycans and low density lipoprotein receptor are involved in hepatitis C virus adsorption.

    Raphaële Germi;Jean-Marc Crance;Daniel Garin;Josette Guimet

  • The Fucose-Binding Lectin from Ralstonia Solanacearum: A New Type of {Beta}-Propeller Architecture Formed by Oligomerization and Interacting with Fucoside, Fucosyllactose, and Plant Xyloglucan.

    Nikola Kostlánová;Edward P. Mitchell;Hugues Lortat-Jacob;Stefan Oscarson

  • Molecular organization of the interferon gamma-binding domain in heparan sulphate.

    H Lortat-Jacob;Jeremy E Turnbull;J A Grimaud

  • Heparin decreases the blood clearance of interferon-gamma and increases its activity by limiting the processing of its carboxyl-terminal sequence.

    Hugues Lortat-Jacob;Frederic Baltzer;Jean-Alexis Grimaud

  • Heparan sulfate targets the HIV-1 envelope glycoprotein gp120 coreceptor binding site.

    Romain R. Vivès;Anne Imberty;Quentin J. Sattentau;Hugues Lortat-Jacob

  • A synthetic CD4–heparan sulfate glycoconjugate inhibits CCR5 and CXCR4 HIV-1 attachment and entry

    Françoise Baleux;Latino Loureiro-Morais;Yael Hersant;Pascal Clayette

  • Inflammatory chemokines direct and restrict leukocyte migration within live tissues as glycan-bound gradients.

    Milka Sarris;Milka Sarris;Jean-Baptiste Masson;Jean-Baptiste Masson;Damien Maurin;Lieke M. Van der Aa;Lieke M. Van der Aa

  • Characterization of Endostatin Binding to Heparin and Heparan Sulfate by Surface Plasmon Resonance and Molecular Modeling ROLE OF DIVALENT CATIONS

    Sylvie Ricard-Blum;Olivier Féraud;Hugues Lortat-Jacob;Anna Rencurosi

  • High-affinity binding of interferon-gamma to a basement membrane complex (matrigel).

    Hugues Lortat-Jacob;H. K. Kleinman;J. A. Grimaud

Frequent Co-Authors

Fernando Arenzana-Seisdedos
Fernando Arenzana-Seisdedos Chinese Academy of Sciences
Anne Imberty
Anne Imberty Grenoble Alpes University
Philippe Lassalle
Philippe Lassalle Institut Pasteur
Catherine Picart
Catherine Picart Grenoble Alpes University
Patricia Rousselle
Patricia Rousselle Institut de Biologie et de Chimie des Protéines
Stephen Cusack
Stephen Cusack European Bioinformatics Institute
Franck Fieschi
Franck Fieschi Grenoble Alpes University
Yves Bourne
Yves Bourne Aix-Marseille University
Malcolm Lyon
Malcolm Lyon University of Manchester
Rob W.H. Ruigrok
Rob W.H. Ruigrok Grenoble Alpes University

External Links

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Best Scientists Citing Hugues Lortat-Jacob

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Robert J. Linhardt

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Franck Fieschi

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Publications: 39

Anne Imberty

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Publications: 36

Fernando Arenzana-Seisdedos

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Publications: 35

Tracy M. Handel

Tracy M. Handel

University of Montana

Publications: 33

Sylvie Ricard-Blum

Sylvie Ricard-Blum

Lyon College

Publications: 28

Yvette van Kooyk

Yvette van Kooyk

Vrije Universiteit Amsterdam

Publications: 27

Anna Bernardi

Anna Bernardi

University of Milan

Publications: 24

Paul Proost

Paul Proost

KU Leuven

Publications: 23

Jean Dubuisson

Jean Dubuisson

Institut Pasteur

Publications: 23

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John A. Kirby

Newcastle University

Publications: 22

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Université Paris Cité

Publications: 22

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David G. Fernig

University of Liverpool

Publications: 22

Eric J. Kremer

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University of Montpellier

Publications: 21

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Institut de Biologie et de Chimie des Protéines

Publications: 20

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