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Fernando Arenzana-Seisdedos

Fernando Arenzana-Seisdedos

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Biology and Biochemistry
China
2023

D-Index & Metrics

Biology and Biochemistry

D-Index
86
Citations
33305
World Ranking
2924
National Ranking
76

Research.com Recognitions

  • 2023 - Research.com Biology and Biochemistry in China Leader Award

Overview

Fernando Arenzana-Seisdedos is affiliated with the Chinese Academy of Sciences in China, focusing research efforts primarily in the fields of Medicine, Biochemistry, Genetics and Molecular Biology, and Immunology and Microbiology. Their work encompasses several subfields, notably Oncology, Cell Biology, Molecular Biology, Virology, and Immunology.

Their research topics span diverse areas including Chemokine receptors and signaling, Proteoglycans and glycosaminoglycans research, HIV Research and Treatment, Multiple Myeloma Research and Treatments, Receptor Mechanisms and Signaling, Monoclonal and Polyclonal Antibodies Research, and Immunotherapy and Immune Responses.

Fernando Arenzana-Seisdedos has published extensively, with selected recent papers including:

  • The CXCL12gamma chemokine immobilized by heparan sulfate on stromal niche cells controls adhesion and mediates drug resistance in multiple myeloma (2021, Journal of Hematology & Oncology)
  • Tracking receptor motions at the plasma membrane reveals distinct effects of ligands on CCR5 dynamics depending on its dimerization status (2022, eLife)
  • Mechanisms of HIV-1 evasion to the antiviral activity of chemokine CXCL12 indicate potential links with pathogenesis (2021, PLoS Pathogens)
  • Is aberrant CD8+ T cell activation by hypertension associated with cardiac injury in severe cases of COVID-19? (2020, Cellular and Molecular Immunology)
  • Discovery of Bis-Imidazoline Derivatives as New CXCR4 Ligands (2023, Molecules)

Frequent coauthors collaborating with Arenzana-Seisdedos include Philippe Colin, Bernard Lagane, Zemin Ren, Hildo C. Lantermans, and Annemieke Kuil, reflecting ongoing partnerships in their research efforts.

The main publication venues for their work consist of the Journal of Hematology & Oncology, bioRxiv (Cold Spring Harbor Laboratory), eLife, PLoS Pathogens, and Cellular and Molecular Immunology.

Best Publications

  • Stromal Fibroblasts Present in Invasive Human Breast Carcinomas Promote Tumor Growth and Angiogenesis through Elevated SDF-1/CXCL12 Secretion

    Akira Orimo;Piyush B. Gupta;Dennis C. Sgroi;Fernando Arenzana-Seisdedos

  • The CXC chemokine SDF-1 is the ligand for LESTR/fusin and prevents infection by T-cell-line-adapted HIV-1

    Estelle Oberlin;Ali Amara;Franc˛oise Bachelerie;Christine Bessia

  • G-CSF induces stem cell mobilization by decreasing bone marrow SDF-1 and up-regulating CXCR4

    Isabelle Petit;Martine Szyper-Kravitz;Arnon Nagler;Meir Lahav

  • The chemokine SDF-1/CXCL12 binds to and signals through the orphan receptor RDC1 in T lymphocytes.

    Karl Balabanian;Bernard Lagane;Simona Infantino;Ken Y.C. Chow

  • Solution structure and basis for functional activity of stromal cell-derived factor-1; dissociation of CXCR4 activation from binding and inhibition of HIV-1.

    Matthew P. Crump;Jiang Hong Gong;Pius Loetscher;Krishna Rajarathnam

  • HGF, SDF-1, and MMP-9 are involved in stress-induced human CD34+ stem cell recruitment to the liver.

    Orit Kollet;Shoham Shivtiel;Yuan Qing Chen;Jenny Suriawinata

  • A mouse model for Chikungunya: young age and inefficient type-I interferon signaling are risk factors for severe disease.

    Thérèse Couderc;Fabrice Chrétien;Clémentine Schilte;Olivier Disson

  • HIV Coreceptor Downregulation as Antiviral Principle: SDF-1α–dependent Internalization of the Chemokine Receptor CXCR4 Contributes to Inhibition of HIV Replication

    Ali Amara;Sylvie Le Gall;Olivier Schwartz;Jean Salamero

  • Induction of the chemokine stromal-derived factor-1 following DNA damage improves human stem cell function

    Tanya Ponomaryov;Amnon Peled;Isabelle Petit;Russell S. Taichman

  • Dendritic‐cell‐specific ICAM3‐grabbing non‐integrin is essential for the productive infection of human dendritic cells by mosquito‐cell‐derived dengue viruses

    Erika Navarro-Sanchez;Ralf Altmeyer;Ali Amara;Olivier Schwartz

  • Multidisciplinary prospective study of mother-to-child chikungunya virus infections on the island of La Réunion.

    Patrick Gérardin;Georges Barau;Alain Michault;Marc Bintner

  • Nuclear localization of I kappa B alpha promotes active transport of NF-kappa B from the nucleus to the cytoplasm

    F. Arenzana-Seisdedos;P. Turpin;M. Rodriguez;D. Thomas

  • Inducible nuclear expression of newly synthesized I kappa B alpha negatively regulates DNA-binding and transcriptional activities of NF-kappa B

    F Arenzana-Seisdedos;J Thompson;M S Rodriguez;F Bachelerie

  • Characterization of Reemerging Chikungunya Virus

    Marion Sourisseau;Clémentine Schilte;Nicoletta Casartelli;Céline Trouillet

  • DC-SIGN and L-SIGN Are High Affinity Binding Receptors for Hepatitis C Virus Glycoprotein E2

    Pierre-Yves Lozach;Hugues Lortat-Jacob;Agnès de Lacroix de Lavalette;Isabelle Staropoli

  • Human Cytomegalovirus Binding to DC-SIGN Is Required for Dendritic Cell Infection and Target Cell trans-Infection

    Franck Halary;Ali Amara;Hugues Lortat-Jacob;Martin Messerle

  • Persistent induction of the chemokine receptor CXCR4 by TGF-beta 1 on synovial T cells contributes to their accumulation within the rheumatoid synovium

    C D Buckley;N Amft;P F Bradfield;D Pilling

  • Stromal cell-derived factor-1alpha associates with heparan sulfates through the first beta-strand of the chemokine.

    Ali Amara;Olivier Lorthioir;Agustin Valenzuela;Aude Magerus

  • HIV blocked by chemokine antagonist

    Fernando Arenzana-Seisdedos;Jean-Louis Virelizier;Dominique Rousset;Ian Clark-Lewis

  • Chemokine Sequestration by Viral Chemoreceptors as a Novel Viral Escape Strategy: Withdrawal of Chemokines from the Environment of Cytomegalovirus-infected Cells

    Bahram Bodaghi;Thomas R. Jones;Donato Zipeto;Claudio Vita

Frequent Co-Authors

Jean-Louis Virelizier
Jean-Louis Virelizier Institut Pasteur
Françoise Bachelerie
Françoise Bachelerie University of Paris-Saclay
Ali Amara
Ali Amara Université Paris Cité
José Alcamí
José Alcamí Instituto de Salud Carlos III
Hugues Lortat-Jacob
Hugues Lortat-Jacob Grenoble Alpes University
Olivier Schwartz
Olivier Schwartz Université Paris Cité
Philippe Desprès
Philippe Desprès University of La Réunion
Manuel S. Rodriguez
Manuel S. Rodriguez Centre national de la recherche scientifique, CNRS
Bernhard Moser
Bernhard Moser Cardiff University
Fabrice Chrétien
Fabrice Chrétien Université Paris Cité

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