World's Best Scientists 2026 revealed!

D-Index & Metrics

Biology and Biochemistry

D-Index
56
Citations
17486
World Ranking
14179
National Ranking
141

Overview

Amnon Peled is affiliated with the Hebrew University of Jerusalem in Israel and specializes in the field of Medicine, with a focus on Oncology, Immunology, Hematology, Hepatology, and Molecular Biology. Their body of work encompasses research on immune cell function and interaction, cancer immunotherapy and biomarkers, liver physiology and pathology, pancreatic and hepatic oncology, phagocytosis and immune regulation, multiple myeloma research and treatments, and chemokine receptors and signaling.

Peled has authored several notable scientific papers, including:

  • BL-8040, a CXCR4 antagonist, in combination with pembrolizumab and chemotherapy for pancreatic cancer: the COMBAT trial, 2020, Nature Medicine
  • Motixafortide and Pembrolizumab Combined to Nanoliposomal Irinotecan, Fluorouracil, and Folinic Acid in Metastatic Pancreatic Cancer: The COMBAT/KEYNOTE-202 Trial, 2021, Clinical Cancer Research
  • Combined hepatocellular-cholangiocarcinoma derives from liver progenitor cells and depends on senescence and IL-6 trans-signaling, 2022, Journal of Hepatology
  • Blocking of Transient Receptor Potential Vanilloid 1 (TRPV1) promotes terminal mitophagy in multiple myeloma, disturbing calcium homeostasis and targeting ubiquitin pathway and bortezomib-induced unfolded protein response, 2020, Journal of Hematology & Oncology
  • CXCL13 chemokine is a novel player in multiple myeloma osteolytic microenvironment, M2 macrophage polarization, and tumor progression, 2022, Journal of Hematology & Oncology

Frequent co-authors in Peled's collaborations include:

  • Michal Abraham
  • Stefan Rose-John
  • Eithan Galun
  • Inbal Mishalian
  • Nofar Rosenberg

Peled's research has been published repeatedly in several key scientific venues, such as:

  • Journal of Hepatology
  • Cancer Research
  • Blood
  • Regular and Young Investigator Award Abstracts
  • Journal of Hematology & Oncology

Their research topics frequently address areas including:

  • Immune Cell Function and Interaction
  • Cancer Immunotherapy and Biomarkers
  • Liver Physiology and Pathology
  • Pancreatic and Hepatic Oncology Research
  • Phagocytosis and Immune Regulation
  • Multiple Myeloma Research and Treatments
  • Chemokine Receptors and Signaling

Best Publications

  • Dependence of human stem cell engraftment and repopulation of NOD/SCID mice on CXCR4

    Amnon Peled;Isabelle Petit;Orit Kollet;Michal Magid

  • G-CSF induces stem cell mobilization by decreasing bone marrow SDF-1 and up-regulating CXCR4

    Isabelle Petit;Martine Szyper-Kravitz;Arnon Nagler;Meir Lahav

  • The chemokine SDF-1 activates the integrins LFA-1, VLA-4, and VLA-5 on immature human CD34(+) cells: role in transendothelial/stromal migration and engraftment of NOD/SCID mice.

    Amnon Peled;Orit Kollet;Tanya Ponomaryov;Isabelle Petit

  • Induction of the chemokine stromal-derived factor-1 following DNA damage improves human stem cell function

    Tanya Ponomaryov;Amnon Peled;Isabelle Petit;Russell S. Taichman

  • The chemokine SDF-1 stimulates integrin-mediated arrest of CD34+ cells on vascular endothelium under shear flow

    Amnon Peled;Valentin Grabovsky;Liliana Habler;Judith Sandbank

  • CD44 and hyaluronic acid cooperate with SDF-1 in the trafficking of human CD34+ stem/progenitor cells to bone marrow.

    Abraham Avigdor;Polina Goichberg;Shoham Shivtiel;Ayelet Dar

  • CXCR4 antagonists: targeting the microenvironment in leukemia and other cancers

    J A Burger;A Peled

  • Role of high expression levels of CXCR4 in tumor growth, vascularization, and metastasis

    Merav Darash-Yahana;Eli Pikarsky;Rinat Abramovitch;Evelyne Zeira

  • Subsecond Induction of α4 Integrin Clustering by Immobilized Chemokines Stimulates Leukocyte Tethering and Rolling on Endothelial Vascular Cell Adhesion Molecule 1 under Flow Conditions

    Valentin Grabovsky;Sara Feigelson;Chun Chen;Diederik A. Bleijs

  • Rapid and efficient homing of human CD34(+)CD38(-/low)CXCR4(+) stem and progenitor cells to the bone marrow and spleen of NOD/SCID and NOD/SCID/B2m(null) mice.

    Orit Kollet;Asaf Spiegel;Amnon Peled;Isabelle Petit

  • CXCL12 expression by invasive trophoblasts induces the specific migration of CD16- human natural killer cells.

    Jacob Hanna;Ori Wald;Debra Goldman-Wohl;Diana Prus

  • BL-8040, a CXCR4 antagonist, in combination with pembrolizumab and chemotherapy for pancreatic cancer: the COMBAT trial

    Bruno Bockorny;Bruno Bockorny;Valerya Semenisty;Teresa Macarulla;Erkut Borazanci

  • Conditional and specific NF-κB blockade protects pancreatic beta cells from diabetogenic agents

    R. Eldor;A. Yeffet;K. Baum;V. Doviner

  • Umbilical cord blood expansion with nicotinamide provides long-term multilineage engraftment

    Mitchell E. Horwitz;Nelson J. Chao;David A. Rizzieri;Gwynn D. Long

  • β2 Microglobulin-deficient (B2mnull) NOD/SCID mice are excellent recipients for studying human stem cell function

    Orit Kollet;Orit Kollet;Amnon Peled;Amnon Peled;Tamara Byk;Tamara Byk;Herzl Ben-Hur;Herzl Ben-Hur

  • Critical Involvement of the Chemotactic Axis CXCR4/Stromal Cell-Derived Factor-1α in the Inflammatory Component of Allergic Airway Disease

    Jose-Angel Gonzalo;Clare M. Lloyd;Amnon Peled;Tracy Delaney

  • Atypical PKC-ζ regulates SDF-1–mediated migration and development of human CD34+ progenitor cells

    Isabelle Petit;Polina Goichberg;Asaf Spiegel;Amnon Peled

  • Human CD34+CXCR4− sorted cells harbor intracellular CXCR4, which can be functionally expressed and provide NOD/SCID repopulation

    Orit Kollet;Isabelle Petit;Joy Kahn;Sarit Samira

  • Nicotinamide, a SIRT1 inhibitor, inhibits differentiation and facilitates expansion of hematopoietic progenitor cells with enhanced bone marrow homing and engraftment

    Tony Peled;Hadas Shoham;Dorit Aschengrau;Dima Yackoubov

  • Unique SDF-1-induced activation of human precursor-B ALL cells as a result of altered CXCR4 expression and signaling

    Asaf Spiegel;Orit Kollet;Amnon Peled;Loya Abel

Frequent Co-Authors

Arnon Nagler
Arnon Nagler Sheba Medical Center
Eithan Galun
Eithan Galun Hebrew University of Jerusalem
Tsvee Lapidot
Tsvee Lapidot Weizmann Institute of Science
Ronen Alon
Ronen Alon Weizmann Institute of Science
Orit Kollet
Orit Kollet Weizmann Institute of Science
Dov Zipori
Dov Zipori Weizmann Institute of Science
Eli Pikarsky
Eli Pikarsky Hebrew University of Jerusalem
Michael Andreeff
Michael Andreeff The University of Texas MD Anderson Cancer Center
Jorge E. Cortes
Jorge E. Cortes Augusta University
Jan A. Burger
Jan A. Burger The University of Texas MD Anderson Cancer Center

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