What is he best known for?
The fields of study he is best known for:
- Gene
- Cancer
- Internal medicine
David T. Scadden mainly focuses on Stem cell, Cell biology, Haematopoiesis, Immunology and Progenitor cell.
David T. Scadden interconnects Endothelial stem cell, Clinical uses of mesenchymal stem cells, Cellular differentiation, Adult stem cell and Bone marrow in the investigation of issues within Stem cell.
His Cell biology research includes elements of Tissue homeostasis and In vivo.
His study in Haematopoiesis is interdisciplinary in nature, drawing from both Cell cycle, Cancer research, Homing and Cell growth.
His Immunology research is multidisciplinary, relying on both Ex vivo and Genetic enhancement.
David T. Scadden has included themes like Niche, Hematopoietic stem cell, Neuroscience and CXCR4 in his Progenitor cell study.
His most cited work include:
- Osteoblastic cells regulate the haematopoietic stem cell niche (2954 citations)
- Mesenchymal and haematopoietic stem cells form a unique bone marrow niche (2327 citations)
- Direct evidence that the VEGF-specific antibody bevacizumab has antivascular effects in human rectal cancer (1739 citations)
What are the main themes of his work throughout his whole career to date?
David T. Scadden mainly investigates Haematopoiesis, Stem cell, Cell biology, Immunology and Bone marrow.
His Haematopoiesis research incorporates themes from Myeloid, Cancer research, Homing, Progenitor cell and Transplantation.
His Stem cell study integrates concerns from other disciplines, such as Clinical uses of mesenchymal stem cells and Adult stem cell.
His Cell biology research is multidisciplinary, incorporating perspectives in Endothelial stem cell, Cell, Cellular differentiation and Niche.
His research integrates issues of Acquired immunodeficiency syndrome and Virology in his study of Immunology.
His work carried out in the field of Bone marrow brings together such families of science as Stromal cell, Mesenchymal stem cell and Endocrinology.
He most often published in these fields:
- Haematopoiesis (40.96%)
- Stem cell (40.10%)
- Cell biology (37.88%)
What were the highlights of his more recent work (between 2015-2021)?
- Haematopoiesis (40.96%)
- Bone marrow (31.57%)
- Cancer research (25.09%)
In recent papers he was focusing on the following fields of study:
David T. Scadden focuses on Haematopoiesis, Bone marrow, Cancer research, Cell biology and Stem cell.
In his work, Cell fate determination is strongly intertwined with Progenitor cell, which is a subfield of Haematopoiesis.
His Bone marrow study contributes to a more complete understanding of Immunology.
The various areas that he examines in his Cancer research study include Cancer, Leukemia and Mesenchymal stem cell.
His Cell biology study combines topics in areas such as Endothelial stem cell, Chromatin, Epigenetics and Cell growth.
His work on Hematopoietic stem cell, Stem cell factor and Hematopoietic Stem Cell Mobilization as part of general Stem cell research is frequently linked to Mobilization, bridging the gap between disciplines.
Between 2015 and 2021, his most popular works were:
- Distinct bone marrow blood vessels differentially regulate haematopoiesis (332 citations)
- A Cellular Taxonomy of the Bone Marrow Stroma in Homeostasis and Leukemia (197 citations)
- Inhibition of Dihydroorotate Dehydrogenase Overcomes Differentiation Blockade in Acute Myeloid Leukemia (172 citations)
In his most recent research, the most cited papers focused on:
- Gene
- Cancer
- Internal medicine
His main research concerns Bone marrow, Haematopoiesis, Progenitor cell, Cell biology and Stem cell.
His Bone marrow research incorporates elements of Lymphopoiesis, Hematology and Cellular differentiation.
His studies in Haematopoiesis integrate themes in fields like Niche, Cancer research, Regeneration, Mesenchymal stem cell and Transplantation.
His research in Progenitor cell intersects with topics in T cell, Cell fate determination and Bioinformatics.
His Cell biology study incorporates themes from Endothelial stem cell, Cell, Genetics and Congenic.
Stem cell is closely attributed to Osteoblast in his research.
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