World's Best Scientists 2026 revealed!
Stuart L. Schreiber

Stuart L. Schreiber

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Best Scientists
2025
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Biology and Biochemistry
USA
2026

D-Index & Metrics

Best Scientists

D-Index
190
Citations
164434
World Ranking
420
National Ranking
281

Biology and Biochemistry

D-Index
184
Citations
160849
World Ranking
62
National Ranking
51

Research.com Recognitions

  • 2026 - Research.com Biology and Biochemistry in United States Leader Award
  • 2025 - Research.com Best Scientists Award
  • 2025 - Research.com Biology and Biochemistry in United States Leader Award
  • 2023 - Research.com Biology and Biochemistry in United States Leader Award
  • 2001 - Promega Biotechnology Research Award, American Society for Microbiology
  • 2000 - Fellow of the American Association for the Advancement of Science (AAAS)
  • 1995 - Fellow of the American Academy of Arts and Sciences
  • 1995 - Member of the National Academy of Sciences
  • 1985 - Fellow of Alfred P. Sloan Foundation

Overview

Stuart L. Schreiber is affiliated with Harvard University in the United States and has contributed extensively to research in biochemistry, genetics, and molecular biology. Their work spans several intersecting fields, including molecular biology, organic chemistry, pulmonary and respiratory medicine, materials chemistry, and immunology.

Among the recent papers associated with their research are:

  • Plasticity of ether lipids promotes ferroptosis susceptibility and evasion, 2020, published in Nature
  • Cytochrome P450 oxidoreductase contributes to phospholipid peroxidation in ferroptosis, 2020, published in Nature Chemical Biology
  • The Rise of Molecular Glues, 2021, published in Cell
  • Selective covalent targeting of GPX4 using masked nitrile-oxide electrophiles, 2020, published in Nature Chemical Biology
  • An Activity-Guided Map of Electrophile-Cysteine Interactions in Primary Human T Cells, 2020, published in Cell

Stuart L. Schreiber's frequent co-authors include:

  • Bruno Melillo
  • Paul A. Clemons
  • Frédéric J. Zécri
  • Benjamin F. Cravatt
  • Karin Briner

The most common venues for their publications are:

  • bioRxiv (Cold Spring Harbor Laboratory) with 19 publications
  • Nature Chemical Biology with 9 publications
  • Journal of the American Chemical Society with 8 publications
  • Nature Communications with 6 publications
  • Cancer Research with 6 publications

Schreiber's main fields of study cover:

  • Biochemistry, Genetics and Molecular Biology (124 publications)
  • Medicine (54 publications)

The key subfields of their research include:

  • Molecular Biology (109 publications)
  • Organic Chemistry (37 publications)
  • Pulmonary and Respiratory Medicine (12 publications)
  • Materials Chemistry (12 publications)
  • Immunology (11 publications)

Notable subjects in Stuart L. Schreiber's body of work are:

  • Protein Degradation and Inhibitors (48 publications)
  • Click Chemistry and Applications (30 publications)
  • Ubiquitin and Proteasome Pathways (30 publications)
  • RNA Modifications and Cancer (22 publications)
  • Chemical Synthesis and Analysis (22 publications)
  • Ferroptosis and Cancer Prognosis (16 publications)
  • Synthesis and Catalytic Reactions (14 publications)

Throughout their career, Stuart L. Schreiber has received several distinctions, including:

  • Promega Biotechnology Research Award, American Society for Microbiology in 2001
  • Fellow of the American Association for the Advancement of Science (AAAS) in 2000
  • Fellow of the American Academy of Arts and Sciences in 1995
  • Member of the National Academy of Sciences in 1995
  • Fellow of Alfred P. Sloan Foundation in 1985

Best Publications

  • Regulation of Ferroptotic Cancer Cell Death by GPX4

    Wan Seok Yang;Rohitha SriRamaratnam;Matthew E. Welsch;Kenichi Shimada

  • A Bivalent Chromatin Structure Marks Key Developmental Genes in Embryonic Stem Cells

    Bradley E. Bernstein;Tarjei S. Mikkelsen;Tarjei S. Mikkelsen;Xiaohui Xie;Michael Kamal

  • Calcineurin is a common target of cyclophilin-cyclosporin A and FKBP-FK506 complexes

    Jun Liu;Jesse D. Farmer;Willam S. Lane;Jeff Friedman

  • A Next Generation Connectivity Map: L1000 Platform and the First 1,000,000 Profiles.

    Aravind Subramanian;Rajiv Narayan;Steven M. Corsello;Steven M. Corsello;David D. Peck

  • The M2 splice isoform of pyruvate kinase is important for cancer metabolism and tumour growth

    Heather R. Christofk;Matthew G. Vander Heiden;Marian H. Harris;Arvind Ramanathan

  • The mechanism of action of cyclosporin A and FK506

    Stuart L Schreiber;Gerald R Crabtree

  • A mammalian protein targeted by G1-arresting rapamycin–receptor complex

    Eric J. Brown;Mark W. Albers;Tae Bum Shin;Kazuo ichikawa

  • Active genes are tri-methylated at K4 of histone H3

    Helena Santos-Rosa;Robert Schneider;Andrew J. Bannister;Julia Sherriff

  • A mammalian histone deacetylase related to the yeast transcriptional regulator Rpd3p.

    Jack Taunton;Christian A. Hassig;Stuart L. Schreiber

  • Small Molecule Inhibitor of Mitotic Spindle Bipolarity Identified in a Phenotype-Based Screen

    Thomas U. Mayer;Tarun M. Kapoor;Stephen J. Haggarty;Stephen J. Haggarty;Randall W. King

  • Inhibition of Proteasome Activities and Subunit-Specific Amino-Terminal Threonine Modification by Lactacystin

    Gabriel Fenteany;Robert F. Standaert;William S. Lane;Soongyu Choi

  • Genomic Maps and Comparative Analysis of Histone Modifications in Human and Mouse

    Bradley E. Bernstein;Bradley E. Bernstein;Bradley E. Bernstein;Michael Kamal;Kerstin Lindblad-Toh;Stefan Bekiranov

  • Lenalidomide Causes Selective Degradation of IKZF1 and IKZF3 in Multiple Myeloma Cells

    Jan Krönke;Namrata D. Udeshi;Anupama Narla;Peter Grauman

  • Nuclear receptor repression mediated by a complex containing SMRT, mSin3A, and histone deacetylase.

    Laszlo Nagy;Hung Ying Kao;Debabrata Chakravarti;Richard J. Lin

  • Dependency of a therapy-resistant state of cancer cells on a lipid peroxidase pathway

    Vasanthi S. Viswanathan;Matthew J. Ryan;Harshil D. Dhruv;Shubhroz Gill

  • Atomic Structures of the Human Immunophilin FKBP-12 Complexes with FK506 and Rapamycin

    Gregory D. Van Duyne;Robert F. Standaert;P.Andrew Karplus;Stuart L. Schreiber

  • Domain-selective small-molecule inhibitor of histone deacetylase 6 (HDAC6)-mediated tubulin deacetylation

    Stephen J. Haggarty;Kathryn M. Koeller;Jason C. Wong;Christina M. Grozinger

  • Mapping copy number variation by population-scale genome sequencing

    Ryan E. Mills;Klaudia Walter;Chip Stewart;Robert E. Handsaker

  • Drug-tolerant persister cancer cells are vulnerable to GPX4 inhibition

    Matthew J. Hangauer;Vasanthi S. Viswanathan;Matthew J. Ryan;Dhruv Bole

  • Retraction Note: Selective killing of cancer cells by a small molecule targeting the stress response to ROS

    Lakshmi Raj;Takao Ide;Aditi U. Gurkar;Michael Foley

Frequent Co-Authors

Paul A. Clemons
Paul A. Clemons Broad Institute
James E. Bradner
James E. Bradner Amgen (United States)
William C. Hahn
William C. Hahn Dana-Farber Cancer Institute
Gerald R. Crabtree
Gerald R. Crabtree Stanford University
Todd R. Golub
Todd R. Golub Harvard University
Stephen J. Haggarty
Stephen J. Haggarty Harvard University
Ramnik J. Xavier
Ramnik J. Xavier Broad Institute
Bradley E. Bernstein
Bradley E. Bernstein Broad Institute
Steven A. Carr
Steven A. Carr Broad Institute
Pablo Tamayo
Pablo Tamayo University of California, San Diego

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