D-Index & Metrics Best Publications

D-Index & Metrics D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines.

Discipline name D-index D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines. Citations Publications World Ranking National Ranking
Molecular Biology D-index 86 Citations 36,023 190 World Ranking 490 National Ranking 284

Overview

What is he best known for?

The fields of study he is best known for:

  • Gene
  • DNA
  • Enzyme

Edward Seto spends much of his time researching Cell biology, Molecular biology, HDAC11, Transcription factor and Histone deacetylase 2. His study in Cell biology is interdisciplinary in nature, drawing from both Genetics, Acetylation, Histone code, Nuclear receptor co-repressor 2 and Histone. His HDAC11 study deals with the bigger picture of Histone deacetylase.

His Histone deacetylase research incorporates themes from Cancer research, Histone methyltransferase and Immune tolerance. His Histone deacetylase 2 research integrates issues from SAP30 and Histone deacetylase 5. His Histone deacetylase 5 research is multidisciplinary, incorporating perspectives in Histone H2A and HDAC10.

His most cited work include:

  • Acetylation and deacetylation of non-histone proteins (1241 citations)
  • A complex containing N-CoR, mSin3 and histone deacetylase mediates transcriptional repression. (1180 citations)
  • The Rpd3/Hda1 family of lysine deacetylases: from bacteria and yeast to mice and men. (930 citations)

What are the main themes of his work throughout his whole career to date?

Edward Seto mainly focuses on Cancer research, Molecular biology, Cell biology, HDAC11 and Histone deacetylase. The concepts of his Cancer research study are interwoven with issues in Cancer cell, Chromatin immunoprecipitation, Immune system and HDAC6. Edward Seto focuses mostly in the field of Molecular biology, narrowing it down to matters related to Transcription and, in some cases, YY1.

His Cell biology research incorporates elements of Genetics, Acetylation, Histone code, Nuclear receptor co-repressor 2 and Histone. His HDAC11 study also includes

  • Histone deacetylase 5 and related Histone deacetylase 2, Histone H2A and Deacetylase activity,
  • HDAC4 that connect with fields like SAP30. Edward Seto has included themes like Cell cycle and Histone methyltransferase in his Histone deacetylase study.

He most often published in these fields:

  • Cancer research (31.25%)
  • Molecular biology (31.25%)
  • Cell biology (29.33%)

What were the highlights of his more recent work (between 2013-2021)?

  • Cancer research (31.25%)
  • Cell biology (29.33%)
  • HDAC11 (27.40%)

In recent papers he was focusing on the following fields of study:

His primary scientific interests are in Cancer research, Cell biology, HDAC11, Histone and Histone deacetylase. His HDAC11 study incorporates themes from In vitro, Histone deacetylase 5, Knockout mouse, Deacetylase activity and Brown adipose tissue. The Histone deacetylase 5 study combines topics in areas such as SAP30, Histone deacetylase 2, HDAC4 and HDAC10.

The study incorporates disciplines such as Epithelial–mesenchymal transition, Chromatin immunoprecipitation, Epigenetics and Acetylation in addition to Histone. His studies deal with areas such as Molecular biology, Ubiquitin, DNA damage and Phosphorylation as well as Histone deacetylase. As a part of the same scientific study, Edward Seto usually deals with the Molecular biology, concentrating on Histone code and frequently concerns with Histone acetyltransferase and MSH3.

Between 2013 and 2021, his most popular works were:

  • Erasers of Histone Acetylation: The Histone Deacetylase Enzymes (643 citations)
  • HDACs and HDAC Inhibitors in Cancer Development and Therapy (315 citations)
  • Divergent roles of histone deacetylase 6 (HDAC6) and histone deacetylase 11 (HDAC11) on the transcriptional regulation of IL10 in antigen presenting cells (77 citations)

In his most recent research, the most cited papers focused on:

  • Gene
  • DNA
  • Enzyme

His main research concerns Cancer research, HDAC11, Histone, Histone deacetylase 2 and Histone deacetylase 5. His Cancer research research is multidisciplinary, relying on both Cyclin A2, Signal transduction, HDAC4, HDAC6 and Regulation of gene expression. His research integrates issues of Chromatin, Transcription and Acetylation in his study of Histone.

His studies in Histone deacetylase 2 integrate themes in fields like Histone methylation and HDAC10. He has researched HDAC10 in several fields, including Nuclear receptor co-repressor 2 and Transcriptional regulation. His work focuses on many connections between Histone deacetylase and other disciplines, such as Molecular biology, that overlap with his field of interest in Cell biology, Muscle contraction, Actin and Cortactin.

This overview was generated by a machine learning system which analysed the scientist’s body of work. If you have any feedback, you can contact us here.

Best Publications

Acetylation and deacetylation of non-histone proteins

Michele A. Glozak;Nilanjan Sengupta;Xiaohong Zhang;Edward Seto.
Gene (2005)

2126 Citations

A complex containing N-CoR, mSin3 and histone deacetylase mediates transcriptional repression.

Thorsten Heinzel;Robert M. Lavinsky;Tina-Marie Mullen;Mats Söderström.
Nature (1997)

1599 Citations

Erasers of Histone Acetylation: The Histone Deacetylase Enzymes

Edward Seto;Minoru Yoshida.
Cold Spring Harbor Perspectives in Biology (2014)

1413 Citations

Lysine acetylation: codified crosstalk with other posttranslational modifications

Xiang Jiao Yang;Xiang Jiao Yang;Edward Seto.
Molecular Cell (2008)

1284 Citations

The Rpd3/Hda1 family of lysine deacetylases: from bacteria and yeast to mice and men.

Xiang-Jiao Yang;Edward Seto.
Nature Reviews Molecular Cell Biology (2008)

1256 Citations

Transcriptional repression by YY1, a human GLI-Krüppel-related protein, and relief of repression by adenovirus E1A protein.

Yang Shi;Edward Seto;Long Sheng Chang;Thomas Shenk.
Cell (1991)

1229 Citations

Histone Deacetylases Associated with the mSin3 Corepressor Mediate Mad Transcriptional Repression

Carol D Laherty;Wen-Ming Yang;Jian-Min Sun;James R Davie.
Cell (1997)

1209 Citations

HATs and HDACs: from structure, function and regulation to novel strategies for therapy and prevention

Yang Xj;Seto E.
Oncogene (2007)

1189 Citations

Inhibition of Histone Deacetylase 6 Acetylates and Disrupts the Chaperone Function of Heat Shock Protein 90 A NOVEL BASIS FOR ANTILEUKEMIA ACTIVITY OF HISTONE DEACETYLASE INHIBITORS

Purva Bali;Michael Pranpat;James Bradner;Maria Balasis.
Journal of Biological Chemistry (2005)

1078 Citations

Histone deacetylases, transcriptional control, and cancer.

W. Douglas Cress;Edward Seto.
Journal of Cellular Physiology (2000)

885 Citations

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