World's Best Scientists 2026 revealed!

D-Index & Metrics

Biology and Biochemistry

D-Index
134
Citations
82145
World Ranking
357
National Ranking
239

Overview

William S. Lane is affiliated with Harvard University in the United States. Their research spans several domains primarily within computer science, with additional contributions to molecular biology and public administration. The main focus lies in artificial intelligence, exploring computational techniques applied to various biological and linguistic data.

The scientist's work covers multiple core topics including:

  • Natural Language Processing Techniques
  • Topic Modeling
  • Ubiquitin and Proteasome Pathways
  • Genomics and Chromatin Dynamics
  • RNA Research and Splicing
  • Social Work Education and Practice
  • Text Readability and Simplification

William S. Lane has contributed to the following notable recent publications:

  • "Interactive Word Completion for Plains Cree," 2022, Proceedings of the 60th Annual Meeting of the Association for Computational Linguistics (Volume 1: Long Papers)
  • "UniMorph 4.0: Universal Morphology," 2022, arXiv (Cornell University)
  • "USP13 interacts with cohesin and regulates its ubiquitination in human cells," 2021, Journal of Biological Chemistry
  • "Reconceptionalizing the Knowledge Base of Social Work: The Imperative for Critical Theories and Perspectives in Social Work Education," 2021, The Journal of Sociology & Social Welfare
  • "P436: Population genome screening identifies previously undiagnosed disease: A case series," 2023, Genetics in Medicine Open

The scientist frequently publishes in diverse venues reflecting interdisciplinary research interests, including:

  • Genetics in Medicine Open
  • Journal of Biological Chemistry
  • The Journal of Sociology & Social Welfare
  • Proceedings of the 60th Annual Meeting of the Association for Computational Linguistics (Volume 1: Long Papers)
  • arXiv (Cornell University)

William S. Lane collaborates regularly with several researchers, including:

  • Esaú Zumaeta Rojas
  • Juan López Bautista
  • Lucas Torroba Hennigen
  • Аziyana V. Bayyr-ool
  • Roberto Zariquiey

The research contributions demonstrate a range of interdisciplinary interests connecting computational methods with biological processes and social sciences. This includes work on ubiquitination pathways, genome screening, natural language processing for indigenous languages, and critical perspectives in social work education.

Best Publications

  • Endostatin: an endogenous inhibitor of angiogenesis and tumor growth.

    Michael S O'Reilly;Thomas Boehm;Yuen Shing;Naomi Fukai

  • HIFα Targeted for VHL-Mediated Destruction by Proline Hydroxylation: Implications for O2 Sensing

    Mircea Ivan;Keiichi Kondo;Haifeng Yang;William Y. Kim

  • Angiostatin: A novel angiogenesis inhibitor that mediates the suppression of metastases by a lewis lung carcinoma

    Michael S. O'Reilly;Michael S. O'Reilly;Lars Holmgren;Lars Holmgren;Yuen Shing;Yuen Shing;Catherine Chen;Catherine Chen

  • A mammalian protein targeted by G1-arresting rapamycin–receptor complex

    Eric J. Brown;Mark W. Albers;Tae Bum Shin;Kazuo ichikawa

  • Inhibition of Proteasome Activities and Subunit-Specific Amino-Terminal Threonine Modification by Lactacystin

    Gabriel Fenteany;Robert F. Standaert;William S. Lane;Soongyu Choi

  • Insulin-stimulated Phosphorylation of a Rab GTPase-activating Protein Regulates GLUT4 Translocation

    Hiroyuki Sano;Susan Kane;Eiko Sano;Cristinel P. Mı̂inea

  • Role of IRS-2 in insulin and cytokine signalling

    Xiao Jian Sun;Ling Mei Wang;Yitao Zhang;Lynne Yenush

  • Specificity and promiscuity among naturally processed peptides bound to HLA-DR alleles.

    R. M. Chicz;R. G. Urban;J. C. Gorga;D. A. A. Vignali

  • Identification of self peptides bound to purified HLA-B27.

    T. S. Jardetzky;W. S. Lane;R. A. Robinson;D. R. Madden

  • The dermatomyositis-specific autoantigen Mi2 is a component of a complex containing histone deacetylase and nucleosome remodeling activities.

    Yi Zhang;Gary LeRoy;Hans-Peter Seelig;William S Lane

  • Predominant naturally processed peptides bound to HLA-DR1 are derived from MHC-related molecules and are heterogeneous in size

    Roman M. Chicz;Robert G. Urban;William S. Lane;Joan C. Gorga;Joan C. Gorga

  • SR proteins: a conserved family of pre-mRNA splicing factors.

    A M Zahler;W S Lane;J A Stolk;M B Roth

  • Rbx1, a component of the VHL tumor suppressor complex and SCF ubiquitin ligase.

    T. Kamura;D. M. Koepp;D. M. Koepp;M. N. Conrad;D. Skowyra

  • Acetylation of the p53 DNA-binding domain regulates apoptosis induction.

    Stephen M. Sykes;Hestia S. Mellert;Hestia S. Mellert;Marc A. Holbert;Keqin Li

  • Structure and expression of the membrane proteoglycan betaglycan, a component of the TGF-β receptor system

    Fernando López-Casillas;Sela Cheifetz;Jacqueline Doody;Janet L. Andres

  • BACH1, a novel helicase-like protein, interacts directly with BRCA1 and contributes to its DNA repair function.

    Sharon B. Cantor;Daphne W. Bell;Shridar Ganesan;Elizabeth M. Kass

  • ARIA, a protein that stimulates acetylcholine receptor synthesis, is a member of the neu ligand family

    Douglas L. Falls;Kenneth M. Rosen;Gabriel Corfas;William S. Lane

  • HDAC6 Modulates Cell Motility by Altering the Acetylation Level of Cortactin

    Xiaohong Zhang;Zhigang Yuan;Yingtao Zhang;Sarah Yong

  • ING tumor suppressor proteins are critical regulators of chromatin acetylation required for genome expression and perpetuation.

    Yannick Doyon;Christelle Cayrou;Mukta Ullah;Anne Julie Landry

  • BRCA1 is associated with a human SWI/SNF-related complex: linking chromatin remodeling to breast cancer.

    Daniel A Bochar;Lai Wang;Hideo Beniya;Alexander Kinev

Frequent Co-Authors

Gustav E. Lienhard
Gustav E. Lienhard Dartmouth College
Danny Reinberg
Danny Reinberg University of Miami
Stuart L. Schreiber
Stuart L. Schreiber Harvard University
Gregory L. Verdine
Gregory L. Verdine Harvard University
Joan Weliky Conaway
Joan Weliky Conaway The University of Texas Southwestern Medical Center
Edward Seto
Edward Seto George Washington University
Jack L. Strominger
Jack L. Strominger Harvard University
Ronald C. Conaway
Ronald C. Conaway The University of Texas Southwestern Medical Center
Vivian Hook
Vivian Hook University of California, San Diego
Ramin Shiekhattar
Ramin Shiekhattar University of Miami

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