World's Best Scientists 2026 revealed!
Jack L. Strominger

Jack L. Strominger

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Best Scientists
2025
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Immunology
USA
2026

D-Index & Metrics

Best Scientists

D-Index
177
Citations
135679
World Ranking
671
National Ranking
420

Immunology

D-Index
178
Citations
134364
World Ranking
39
National Ranking
28

Research.com Recognitions

  • 2026 - Research.com Immunology in United States Leader Award
  • 2025 - Research.com Best Scientists Award
  • 2025 - Research.com Immunology in United States Leader Award
  • 2020 - Distinguished Fellows of the American Association of Immunologists (AAI)
  • 2010 - AAI Excellence in Mentoring Award, American Association of Immunologists
  • 1999 - Japan Prize for the elucidation of the three dimensional structures of class I and class II human histocompatibility antigens and their bound peptides.
  • 1996 - Paul Ehrlich and Ludwig Darmstaedter Prize
  • 1995 - Albert Lasker Award for Basic Medical Research, Lasker Foundation
  • 1975 - Member of the National Academy of Medicine (NAM)
  • 1974 - Fellow of John Simon Guggenheim Memorial Foundation
  • 1970 - Fellow of the American Association for the Advancement of Science (AAAS)
  • 1970 - Member of the National Academy of Sciences
  • 1967 - Fellow of the American Academy of Arts and Sciences

Overview

Jack L. Strominger is affiliated with Harvard University in the United States. Their research primarily spans the fields of Medicine and Immunology and Microbiology, with a notable focus on Immunology as a subfield. Their work also extends into Obstetrics and Gynecology, Public Health, Environmental and Occupational Health, Epidemiology, and Reproductive Medicine.

The scientist's research concentrates on several main topics including:

  • Reproductive System and Pregnancy
  • Preterm Birth and Chorioamnionitis
  • Pregnancy and Preeclampsia Studies
  • COVID-19 Impact on Reproduction
  • Ectopic Pregnancy Diagnosis and Management
  • Pregnancy and Medication Impact
  • Immune Cell Function and Interaction

Frequent publication venues for their work include:

  • Proceedings of the National Academy of Sciences
  • Cell
  • The Journal of Immunology
  • Journal of Reproductive Immunology
  • Immunology

Some of their recent papers are:

  • Decidual NK Cells Transfer Granulysin to Selectively Kill Bacteria in Trophoblasts, 2020, Cell
  • Three types of HLA-G+ extravillous trophoblasts that have distinct immune regulatory properties, 2020, Proceedings of the National Academy of Sciences
  • Human Term Pregnancy Decidual NK Cells Generate Distinct Cytotoxic Responses, 2020, The Journal of Immunology
  • Decidual NK cells kill Zika virus-infected trophoblasts, 2021, Proceedings of the National Academy of Sciences
  • ELF3 activated by a superenhancer and an autoregulatory feedback loop is required for high-level HLA-C expression on extravillous trophoblasts, 2021, Proceedings of the National Academy of Sciences

Frequent collaborators of Jack L. Strominger include:

  • Tamara Tilburgs
  • Torsten Meißner
  • Ângela C. Crespo
  • Judy Lieberman
  • Sarika Kshirsagar

Over the course of their career, they have received several awards, including:

  • Distinguished Fellows of the American Association of Immunologists (AAI), 2020
  • AAI Excellence in Mentoring Award, American Association of Immunologists, 2010
  • Japan Prize, 1999, for the elucidation of the three dimensional structures of class I and class II human histocompatibility antigens and their bound peptides
  • Paul Ehrlich and Ludwig Darmstaedter Prize, 1996
  • Albert Lasker Award for Basic Medical Research, Lasker Foundation, 1995
  • Member of the National Academy of Medicine (NAM), 1975
  • Fellow of John Simon Guggenheim Memorial Foundation, 1974
  • Fellow of the American Association for the Advancement of Science (AAAS), 1970
  • Member of the National Academy of Sciences, 1970
  • Fellow of the American Academy of Arts and Sciences, 1967

Best Publications

  • Structure of the human class I histocompatibility antigen, HLA-A2.

    P. J. Bjorkman;M. A. Saper;B. Samraoui;W. S. Bennett

  • Nomenclature for factors of the HLA system, 2010.

    S G. E. Marsh;E. D. Albert;W. F. Bodmer;R. E. Bontrop

  • A MODIFIED COLORIMETRIC METHOD FOR THE ESTIMATION OF N-ACETYLAMINO SUGARS

    José L. Reissig;Jack L. Strominger;Luis Federico Leloir

  • The foreign antigen binding site and T cell recognition regions of class I histocompatibility antigens

    P. J. Bjorkman;P. J. Bjorkman;P. J. Bjorkman;M. A. Saper;B. Samraoui;W. S. Bennett;W. S. Bennett

  • Three-dimensional structure of the human class II histocompatibility antigen HLA-DR1

    Jerry H. Brown;Theodore S. Jardetzky;Joan C. Gorga;Joan C. Gorga;Lawrence J. Stern;Lawrence J. Stern

  • Crystal structure of the human class II MHC protein HLA-DR1 complexed with an influenza virus peptide

    Lawrence J. Stern;Jerry H. Brown;Theodore S. Jardetzky;Joan C. Gorga

  • Molecular mimicry in T cell-mediated autoimmunity: Viral peptides activate human T cell clones specific for myelin basic protein

    Kai W Wucherpfennig;Jack L Strominger

  • Nomenclature for factors of the HLA system, 1995

    J G Bodmer;S G Marsh;Albert;W F Bodmer

  • Nomenclature for factors of the HLA system, 1994

    Julia G. Bodmer;Steven G. E. Marsh;Ekkehard D. Albert;Walter F. Bodmer

  • Mechanism of action of penicillins: a proposal based on their structural similarity to acyl-D-alanyl-D-alanine.

    Donald J. Tipper;Jack L. Strominger

  • Identification of a putative second T-cell receptor.

    Michael B. Brenner;Michael B. Brenner;Joanne McLean;Deno P. Dialynas;Jack L. Strominger

  • Epstein-Barr virus receptor of human B lymphocytes is the C3d receptor CR2.

    J D Fingeroth;J J Weis;T F Tedder;J L Strominger

  • Recognition of haemagglutinins on virus-infected cells by NKp46 activates lysis by human NK cells

    Ofer Mandelboim;Niva Lieberman;Marianna Lev;Lada Paul

  • Interaction between CD4 and class II MHC molecules mediates cell adhesion

    Carolyn Doyle;Jack L. Strominger

  • Specificity and promiscuity among naturally processed peptides bound to HLA-DR alleles.

    R. M. Chicz;R. G. Urban;J. C. Gorga;D. A. A. Vignali

  • The selective downregulation of class I major histocompatibility complex proteins by HIV-1 protects HIV-infected cells from NK cells.

    George B Cohen;George B Cohen;Rajesh T Gandhi;Daniel M Davis;Ofer Mandelboim

  • Human Decidual Natural Killer Cells Are a Unique NK Cell Subset with Immunomodulatory Potential

    Louise A. Koopman;Hernan D. Kopcow;Basya Rybalov;Jonathan E. Boyson

  • Predominant naturally processed peptides bound to HLA-DR1 are derived from MHC-related molecules and are heterogeneous in size

    Roman M. Chicz;Robert G. Urban;William S. Lane;Joan C. Gorga;Joan C. Gorga

  • Extreme Th1 bias of invariant Vα24JαQ T cells in type 1 diabetes

    S. Brian Wilson;Sally C. Kent;Kurt T. Patton;Tihamer Orban

  • Three distinct antigens associated with human T-lymphocyte-mediated cytolysis: LFA-1, LFA-2, and LFA-3.

    Francisco Sanchez-Madrid;Alan M. Krensky;Carl F. Ware;Elizabeth Robbins

  • The structure of HLA-B27 reveals nonamer self-peptides bound in an extended conformation.

    D. R. Madden;J. C. Gorga;J. C. Gorga;J. L. Strominger;D. C. Wiley;D. C. Wiley

  • The three-dimensional structure of HLA-B27 at 2.1 Å resolution suggests a general mechanism for tight peptide binding to MHC

    Dean R. Madden;Joan C. Gorga;Jack L. Strominger;Don C. Wiley;Don C. Wiley

  • Pillars Article: The foreign antigen binding site and T cell recognition regions of class I histocompatibility antigens.

    P. J. Bjorkman;M. A. Saper;B. Samraoui;W. S. Bennett

Frequent Co-Authors

Peter Parham
Peter Parham Stanford University
Don C. Wiley
Don C. Wiley Harvard University
Steven J. Burakoff
Steven J. Burakoff Icahn School of Medicine at Mount Sinai
Michael S. Krangel
Michael S. Krangel Duke University
Kai W. Wucherpfennig
Kai W. Wucherpfennig Harvard University
Walter F. Bodmer
Walter F. Bodmer University of Oxford
James C. Kaufman
James C. Kaufman University of Connecticut
Martin E. Hemler
Martin E. Hemler Harvard University
Ekkehard D. Albert
Ekkehard D. Albert Ludwig-Maximilians-Universität München
Harry T. Orr
Harry T. Orr University of Minnesota

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