World's Best Scientists 2026 revealed!

D-Index & Metrics

Biology and Biochemistry

D-Index
112
Citations
45282
World Ranking
902
National Ranking
565

Overview

Martin E. Hemler is affiliated with Harvard University in the United States. Their research primarily focuses on the field of Chemistry, with specific contributions in subfields including Spectroscopy, Materials Chemistry, Computational Theory and Mathematics, and Pharmacology.

The main topics explored in their work include:

  • Advanced Proteomics Techniques and Applications
  • Mass Spectrometry Techniques and Applications
  • Enzyme Structure and Function
  • Computational Drug Discovery Methods
  • Pharmacogenetics and Drug Metabolism

Hemler has coauthored papers with researchers such as Chandan Sharma, Wei Yang, Hanno Steen, and Michael R. Freeman, with multiple collaborations especially noted with Chandan Sharma.

Their recent publications include:

  • Antioxidant functions of DHHC3 suppress anti-cancer drug activities, 2020, published in Cellular and Molecular Life Sciences
  • Antioxidant and Anticancer Functions of Protein Acyltransferase DHHC3, 2022, published in Antioxidants

Both papers focus on the biological and chemical roles of DHHC3, particularly its impact on antioxidant activity and cancer-related mechanisms.

Frequently chosen venues for publication are Cellular and Molecular Life Sciences and Antioxidants, demonstrating engagement with journals that cover molecular biology and biochemical research topics.

Best Publications

  • VCAM-1 on activated endothelium interacts with the leukocyte integrin VLA-4 at a site distinct from the VLA-4/Fibronectin binding site

    Mariano J. Elices;Laurelee Osborn;Yoshikazu Takada;Carol Crouse

  • VLA proteins in the integrin family : structures, functions and their role on leukocytes

    Martin E. Hemler

  • Tetraspanin functions and associated microdomains.

    Martin E. Hemler

  • Tetraspanin Proteins Mediate Cellular Penetration, Invasion, and Fusion Events and Define a Novel Type of Membrane Microdomain

    Martin E. Hemler

  • Regulation of cell adhesion receptors by transforming growth factor-beta. Concomitant regulation of integrins that share a common beta 1 subunit.

    Jyrki Heino;Ronald A. Ignotz;Martin E. Hemler;Carol Crouse

  • The integrin VLA-4 supports tethering and rolling in flow on VCAM-1.

    Ronen Alon;Paul D. Kassner;Michelle Woldemar Carr;Erik B. Finger

  • The VLA protein family. Characterization of five distinct cell surface heterodimers each with a common 130,000 molecular weight beta subunit.

    M E Hemler;C Huang;L Schwarz

  • Evidence for a peroxide-initiated free radical mechanism of prostaglandin biosynthesis.

    M E Hemler;W E Lands

  • Regulation of MMP-1 and MMP-2 production through CD147/extracellular matrix metalloproteinase inducer interactions.

    Jianxin Sun;Martin E. Hemler

  • Characterization of a monoclonal antibody (4F2) that binds to human monocytes and to a subset of activated lymphocytes.

    B F Haynes;M E Hemler;D L Mann;G S Eisenbarth

  • Receptor functions for the integrin VLA-3: fibronectin, collagen, and laminin binding are differentially influenced by Arg-Gly-Asp peptide and by divalent cations.

    M J Elices;L A Urry;M E Hemler

  • Purification of the cyclooxygenase that forms prostaglandins. Demonstration of two forms of iron in the holoenzyme.

    M Hemler;W E Lands

  • Glycoproteins of 210,000 and 130,000 m.w. on activated T cells: cell distribution and antigenic relation to components on resting cells and T cell lines.

    M E Hemler;F Sanchez-Madrid;T J Flotte;A M Krensky

  • Role of beta 1 and beta 2 integrins in the adhesion of human CD34hi stem cells to bone marrow stroma.

    J Teixidó;M E Hemler;J S Greenberger;P Anklesaria

  • Functional domains in tetraspanin proteins.

    Christopher S. Stipp;Tatiana V. Kolesnikova;Martin E. Hemler

  • Specific tetraspanin functions

    Martin E. Hemler

  • The pathophysiologic role of alpha 4 integrins in vivo.

    R R Lobb;M E Hemler

  • Integrin associated proteins.

    Martin E Hemler

  • The human integrin VLA-2 is a collagen receptor on some cells and a collagen/laminin receptor on others

    Mariano J. Elices;Martin E. Hemler

  • Prostaglandin biosynthesis can be triggered by lipid peroxides.

    Martin E. Hemler;Harold W. Cook;William E.M. Lands

Frequent Co-Authors

Jack L. Strominger
Jack L. Strominger Harvard University
Yoshikazu Takada
Yoshikazu Takada University of California, Davis
Roy R. Lobb
Roy R. Lobb Biogen (United States)
Michael B. Brenner
Michael B. Brenner Harvard Medical School
Barton F. Haynes
Barton F. Haynes Duke University
Francisco Sánchez-Madrid
Francisco Sánchez-Madrid Autonomous University of Madrid
Timothy A. Springer
Timothy A. Springer Boston Children's Hospital
Jeffrey M. Bergelson
Jeffrey M. Bergelson Children's Hospital of Philadelphia
Lan Bo Chen
Lan Bo Chen Harvard University
Robert W. Finberg
Robert W. Finberg University of Massachusetts Chan Medical School

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