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Biology and Biochemistry

D-Index
55
Citations
8467
World Ranking
15276
National Ranking
327

Overview

Laura Sánchez is affiliated with the University of Santiago de Compostela in Spain. Their research spans multiple scientific disciplines, with a significant focus on biochemistry, genetics, molecular biology, and medicine. Within these fields, Sánchez has contributed extensively to areas such as molecular biology, cell biology, oncology, materials chemistry, and cancer research.

The scientist's work encompasses a variety of specialized topics including zebrafish biomedical research applications, cancer cells and metastasis, crystallization and solubility studies, CRISPR and genetic engineering, X-ray diffraction in crystallography, microRNA in disease regulation, and metal complexes synthesis and properties.

Laura Sánchez has authored or co-authored several recent papers notable for their focus on cancer biology and experimental models. Some of these include:

  • "Exploiting oxidative phosphorylation to promote the stem and immunoevasive properties of pancreatic cancer stem cells," 2020, published in Nature Communications
  • "Circulating Tumor Cells Characterization Revealed TIMP1 as a Potential Therapeutic Target in Ovarian Cancer," 2020, published in Cells
  • "The multifaceted roles of gasdermins in cancer biology and oncologic therapies," 2021, published in Biochimica et Biophysica Acta (BBA) - Reviews on Cancer
  • "Dysregulated splicing factor SF3B1 unveils a dual therapeutic vulnerability to target pancreatic cancer cells and cancer stem cells with an anti-splicing drug," 2021, published in Journal of Experimental & Clinical Cancer Research
  • "Modeling Cancer Using Zebrafish Xenografts: Drawbacks for Mimicking the Human Microenvironment," 2020, published in Cells

Sánchez's frequent coauthors include Antón Barreiro-Iglesias, Pablo Cabezas-Sainz, Álvaro J. Arana, Ana Quelle-Regaldie, and Juan A. Rubiolo, reflecting collaborative engagement across various research projects.

The scientist frequently publishes in venues such as bioRxiv (Cold Spring Harbor Laboratory), The Cambridge Structural Database, International Journal of Molecular Sciences, Preprints.org, and Cells. These journals and repositories are consistent with the interdisciplinary nature of Sánchez's research, which bridges molecular studies with biomedical applications.

Best Publications

  • KIT mutation in mast cells and other bone marrow hematopoietic cell lineages in systemic mast cell disorders: a prospective study of the Spanish Network on Mastocytosis (REMA) in a series of 113 patients.

    Andres C Garcia-Montero;Maria Jara-Acevedo;Cristina Teodosio;Maria Luz Sanchez

  • Human Induced Pluripotent Stem Cells Develop Teratoma More Efficiently and Faster Than Human Embryonic Stem Cells Regardless the Site of Injection

    Ivan Gutierrez‐Aranda;Veronica Ramos‐Mejia;Clara Bueno;Martin Munoz‐Lopez

  • Recent advances in the understanding of mastocytosis: the role of KIT mutations*

    Alberto Orfao;Andrés C. Garcia-Montero;Laura Sanchez;Luis Escribano

  • Embryonic stem cell-specific miR302-367 cluster: human gene structure and functional characterization of its core promoter.

    Alicia Barroso-delJesus;Cristina Romero-López;Gema Lucena-Aguilar;Gema Lucena-Aguilar;Gustavo J. Melen

  • Genetic architecture of sex determination in fish: applications to sex ratio control in aquaculture.

    Paulino Martínez;Ana M. Viñas;Laura Sánchez;Noelia Díaz

  • Human ESCs predisposition to karyotypic instability: Is a matter of culture adaptation or differential vulnerability among hESC lines due to inherent properties?

    Puri Catalina;Rosa Montes;Gertru Ligero;Laura C. Sanchez

  • Engineered LINE-1 retrotransposition in nondividing human neurons.

    Angela Macia;Thomas J. Widmann;Sara R. Heras;Veronica Ayllon

  • Analysis of qPCR reference gene stability determination methods and a practical approach for efficiency calculation on a turbot ( Scophthalmus maximus ) gonad dataset

    Diego Robledo;Jorge Hernández-Urcera;Rosa M Cal;Belén G Pardo

  • Enrichment of human ESC-derived multipotent mesenchymal stem cells with immunosuppressive and anti-inflammatory properties capable to protect against experimental inflammatory bowel disease.

    Laura Sánchez;Iván Gutierrez‐Aranda;Gertrudis Ligero;Ruth Rubio

  • LINE-1 Evasion of Epigenetic Repression in Humans

    Francisco J. Sanchez-Luque;Francisco J. Sanchez-Luque;Marie-Jeanne H.C. Kempen;Marie-Jeanne H.C. Kempen;Patricia Gerdes;Dulce B. Vargas-Landin;Dulce B. Vargas-Landin

  • Identification of the Major Sex-Determining Region of Turbot ( Scophthalmus maximus )

    Paulino Martínez;Carmen Bouza;Miguel Hermida;Jesús Fernández

  • The Nodal inhibitor Lefty is negatively modulated by the microRNA miR-302 in human embryonic stem cells

    Alicia Barroso-delJesus;Gema Lucena-Aguilar;Laura Sanchez;Gertrudis Ligero

  • A microsatellite genetic map of the turbot (Scophthalmus maximus).

    Carmen Bouza;Miguel Hermida;Belén G. Pardo;Carlos Fernández

  • Induction of triploidy in the turbot (Scophthalmus maximus). I. Ploidy determination and the effects of cold shocks

    Francesc Piferrer;Rosa Mª Cal;Blanca Álvarez-Blázquez;Laura Sánchez

  • Feeder-free maintenance of hESCs in mesenchymal stem cell-conditioned media: distinct requirements for TGF-beta and IGF-II.

    Rosa Montes;Gertrudis Ligero;Laura Sanchez;Purificación Catalina

  • Potential sources of error in parentage assessment of turbot (Scophthalmus maximus) using microsatellite loci

    Jaime Castro;Carmen Bouza;Pablo Presa;Ania Pino-Querido

  • Genome-wide de novo L1 Retrotransposition Connects Endonuclease Activity with Replication.

    Diane A. Flasch;Ángela Macia;Laura Sánchez;Mats Ljungman

  • Phylogenetic analysis of flatfish (Order Pleuronectiformes) based on mitochondrial 16s rDNA sequences

    Belén G. Pardo;Annie Machordom;Fausto Foresti;Fábio Porto-Foresti

  • Differential stocking incidence in brown trout (Salmo trutta) populations from Northwestern Spain

    P. Martinez;J. Arias;J. Castro;L. Sanchez

  • Allozyme and microsatellite diversity in natural and domestic populations of turbot (Scophthalmus maximus) in comparison with other Pleuronectiformes

    C Bouza;P Presa;J Castro;L Sánchez

Frequent Co-Authors

Paulino Martínez
Paulino Martínez University of Santiago de Compostela
Jose L. Garcia-Perez
Jose L. Garcia-Perez University of Granada
Pablo Menendez
Pablo Menendez University of Barcelona
Francesc Piferrer
Francesc Piferrer Spanish National Research Council
Gema Moreno-Bueno
Gema Moreno-Bueno The University of Texas MD Anderson Cancer Center
Luis M. Botana
Luis M. Botana University of Santiago de Compostela
John J. Miles
John J. Miles James Cook University
Luis Escribano
Luis Escribano University of Salamanca
Richard R. Meehan
Richard R. Meehan University of Edinburgh
Christopher Heeschen
Christopher Heeschen Shanghai Jiao Tong University

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