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Biology and Biochemistry

D-Index
72
Citations
21027
World Ranking
6221
National Ranking
2926

Overview

Gema Moreno-Bueno is affiliated with The University of Texas MD Anderson Cancer Center in the United States. Their research spans multiple domains within biochemistry, genetics, molecular biology, and medicine, with particular focus on molecular biology, oncology, cancer research, immunology, and obstetrics and gynecology.

The scope of Moreno-Bueno's work covers extensive areas including inflammasome and immune disorders, cancer genomics and diagnostics, treatments for endometrial and cervical cancers, cancer cells and metastasis, epigenetics and DNA methylation, cancer-related gene regulation, and ubiquitin and proteasome pathways.

Frequently publishing in scientific journals, Moreno-Bueno has contributed to venues such as:

  • bioRxiv (Cold Spring Harbor Laboratory)
  • Cancers
  • Cancer Research
  • Journal of Experimental & Clinical Cancer Research
  • Frontiers in Oncology

Recent publications include:

  • Obesity and Breast Cancer: A Paradoxical and Controversial Relationship Influenced by Menopausal Status (2021), Frontiers in Oncology
  • Circulating Tumor Cells Characterization Revealed TIMP1 as a Potential Therapeutic Target in Ovarian Cancer (2020), Cells
  • The multifaceted roles of gasdermins in cancer biology and oncologic therapies (2021), Biochimica et Biophysica Acta (BBA) - Reviews on Cancer
  • Distinct GSDMB protein isoforms and protease cleavage processes differentially control pyroptotic cell death and mitochondrial damage in cancer cells (2023), Cell Death and Differentiation
  • Macrophages direct cancer cells through a LOXL2-mediated metastatic cascade in pancreatic ductal adenocarcinoma (2022), Gut

Moreno-Bueno works collaboratively with several frequent co-authors including David Sarrió, Eva Díaz, Sara S. Oltra, Rafael López-López, and Laura Muinelo-Romay.

Best Publications

  • Melanoma exosomes educate bone marrow progenitor cells toward a pro-metastatic phenotype through MET

    Héctor Peinado;Maša Alečković;Simon Lavotshkin;Irina Matei

  • Epithelial-Mesenchymal Transition in Breast Cancer Relates to the Basal-like Phenotype

    David Sarrió;Socorro María Rodriguez-Pinilla;David Hardisson;Amparo Cano

  • Metastatic Colonization Requires the Repression of the Epithelial-Mesenchymal Transition Inducer Prrx1

    Oscar H. Ocaña;Rebeca Córcoles;Ángels Fabra;Gema Moreno-Bueno;Gema Moreno-Bueno

  • Transcriptional regulation of cell polarity in EMT and cancer.

    Gema Moreno-Bueno;Francisco Portillo;Amparo Cano

  • Correlation of Snail expression with histological grade and lymph node status in breast carcinomas.

    Maria J Blanco;Gema Moreno-Bueno;David Sarrio;Annamaria Locascio

  • Combined Epidermal Growth Factor Receptor Targeting with the Tyrosine Kinase Inhibitor Gefitinib (ZD1839) and the Monoclonal Antibody Cetuximab (IMC-C225) Superiority Over Single-Agent Receptor Targeting

    Pablo Matar;Federico Rojo;Raúl Cassia;Gema Moreno-Bueno

  • Genetic profiling of epithelial cells expressing E-cadherin repressors reveals a distinct role for Snail, Slug, and E47 factors in epithelial-mesenchymal transition.

    Gema Moreno-Bueno;Eva Cubillo;David Sarrió;Héctor Peinado

  • Abnormalities of the APC/β-catenin pathway in endometrial cancer

    Gema Moreno-Bueno;David Hardisson;Carolina Sánchez;David Sarrió

  • Sox2: a possible driver of the basal-like phenotype in sporadic breast cancer.

    Socorro M Rodriguez-Pinilla;David Sarrio;Gema Moreno-Bueno;Yolanda Rodriguez-Gil

  • Epigenetic and genetic alterations of APC and CDH1 genes in lobular breast cancer: relationships with abnormal E-cadherin and catenin expression and microsatellite instability.

    David Sarrió;Gema Moreno-Bueno;David Hardisson;Carolina Sánchez-Estévez

  • Micro-RNA signature of the epithelial–mesenchymal transition in endometrial carcinosarcoma

    María Ángeles Castilla;Gema Moreno-Bueno;Laura Romero-Pérez;Koen Van De Vijver

  • Cytoplasmic localization of p120ctn and E-cadherin loss characterize lobular breast carcinoma from preinvasive to metastatic lesions

    David Sarrió;Belén Pérez-Mies;David Hardisson;Gema Moreno-Bueno

  • The morphological and molecular features of the epithelial-to-mesenchymal transition

    Gema Moreno-Bueno;Héctor Peinado;Héctor Peinado;Patricia Molina;David Olmeda;David Olmeda

  • EMT: Present and future in clinical oncology.

    Patricia G. Santamaria;Gema Moreno-Bueno;Gema Moreno-Bueno;Francisco Portillo;Amparo Cano

  • SNAI1 is required for tumor growth and lymph node metastasis of human breast carcinoma MDA-MB-231 cells

    David Olmeda;Gema Moreno-Bueno;Juana María Flores;Àngels Fabra

  • Lysyl Oxidase-Like 2 as a New Poor Prognosis Marker of Squamous Cell Carcinomas

    Héctor Peinado;Gema Moreno-Bueno;David Hardisson;Eduardo Pérez-Gómez

  • Cannabinoids reduce ErbB2-driven breast cancer progression through Akt inhibition

    María M Caffarel;Clara Andradas;Emilia Mira;Eduardo Pérez-Gómez

  • Endometrial carcinoma: molecular alterations involved in tumor development and progression.

    A Yeramian;G Moreno-Bueno;X Dolcet;L Catasus

  • Role of microRNA in epithelial to mesenchymal transition and metastasis and clinical perspectives

    Antonio Díaz-López;Gema Moreno-Bueno;Amparo Cano

  • Differential Gene Expression Profile in Endometrioid and Nonendometrioid Endometrial Carcinoma STK15 Is Frequently Overexpressed and Amplified in Nonendometrioid Carcinomas

    Gema Moreno-Bueno;Carolina Sánchez-Estévez;Raúl Cassia;Sandra Rodríguez-Perales

Frequent Co-Authors

José Palacios
José Palacios Ramón y Cajal Hospital (Hospital Universitario Ramón y Cajal)
Amparo Cano
Amparo Cano Spanish National Research Council
Xavier Matias-Guiu
Xavier Matias-Guiu Hospital Universitari Arnau de Vilanova
Héctor Peinado
Héctor Peinado Spanish National Cancer Research Centre
Jaime Prat
Jaime Prat Autonomous University of Barcelona
Manel Esteller
Manel Esteller Josep Carreras Leukaemia Research Institute
Joaquín Arribas
Joaquín Arribas Institució Catalana de Recerca i Estudis Avançats
Manuel Guzmán
Manuel Guzmán Complutense University of Madrid
Esther Oliva
Esther Oliva Harvard University
Justo P. Castaño
Justo P. Castaño University of Córdoba

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