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Mark Hochstrasser

Mark Hochstrasser

Yale University
United States

D-Index & Metrics

Biology and Biochemistry

D-Index
84
Citations
43681
World Ranking
3232
National Ranking
1635

Mark Hochstrasser publication distribution in Biology and Biochemistry in 2026

The chart shows the distribution of publications by all Research.com ranked scientists in the field of Biology and Biochemistry in 2026. The highlighted bar marks where Mark Hochstrasser sits on this spectrum.

47–56 publications: 8 scientists 57–66 publications: 35 scientists 67–76 publications: 106 scientists 77–86 publications: 231 scientists 87–96 publications: 413 scientists 97–106 publications: 546 scientists 107–116 publications: 704 scientists 117–126 publications: 848 scientists 127–136 publications: 980 scientists 137–146 publications: 942 scientists 147–156 publications: 969 scientists 157–166 publications: 949 scientists 167–176 publications: 951 scientists 177–186 publications: 915 scientists 187–196 publications: 787 scientists 197–206 publications: 840 scientists 207–216 publications: 733 scientists 217–226 publications: 708 scientists 227–236 publications: 651 scientists 237–246 publications: 605 scientists 247–256 publications: 510 scientists 257–266 publications: 524 scientists 267–276 publications: 434 scientists 277–286 publications: 417 scientists 287–296 publications: 350 scientists 297–306 publications: 363 scientists 307–316 publications: 315 scientists 317–326 publications: 296 scientists 327–336 publications: 261 scientists 337–346 publications: 240 scientists 347–356 publications: 219 scientists 357–366 publications: 196 scientists 367–376 publications: 154 scientists 377–386 publications: 161 scientists 387–396 publications: 155 scientists 397–406 publications: 145 scientists 407–416 publications: 124 scientists 417–426 publications: 112 scientists 427–436 publications: 132 scientists 437–446 publications: 116 scientists 447–456 publications: 99 scientists 457–466 publications: 81 scientists 467–476 publications: 91 scientists 477–486 publications: 80 scientists 487–496 publications: 80 scientists 497–506 publications: 59 scientists 507–516 publications: 36 scientists 517–526 publications: 46 scientists 527–536 publications: 54 scientists 537–546 publications: 44 scientists 547–556 publications: 43 scientists 557–566 publications: 43 scientists 567–576 publications: 42 scientists 577–586 publications: 25 scientists 587–596 publications: 34 scientists 597–606 publications: 23 scientists 607–616 publications: 33 scientists 617–626 publications: 31 scientists 627–636 publications: 27 scientists 637–646 publications: 25 scientists 647–656 publications: 28 scientists 657–666 publications: 34 scientists 667–676 publications: 18 scientists 677–686 publications: 16 scientists 687–696 publications: 10 scientists 697–706 publications: 12 scientists 707–716 publications: 21 scientists 717–726 publications: 12 scientists 727–736 publications: 12 scientists 737–746 publications: 10 scientists 747–756 publications: 7 scientists 757–766 publications: 13 scientists 767–776 publications: 15 scientists 777–786 publications: 13 scientists 787–796 publications: 9 scientists 797–806 publications: 9 scientists 807–816 publications: 7 scientists 817–826 publications: 4 scientists 827–836 publications: 9 scientists 837–846 publications: 7 scientists 847–856 publications: 3 scientists 857–866 publications: 5 scientists 867–876 publications: 5 scientists 877–886 publications: 11 scientists 887–896 publications: 3 scientists 897–906 publications: 4 scientists 907–916 publications: 7 scientists 917–926 publications: 5 scientists 927–936 publications: 6 scientists 937–946 publications: 6 scientists 947–956 publications: 3 scientists 957–966 publications: 7 scientists 967–976 publications: 2 scientists 977–986 publications: 2 scientists 987–996 publications: 1 scientists 997–1,006 publications: 5 scientists 1,007–1,016 publications: 2 scientists 1,017–1,026 publications: 2 scientists 1,027 publications: 1 scientists 1,028+ publications: 100 scientists
47 publications 1,028+

This scientist: 209 publications — 53rd percentile

53% of scientists in this discipline score the same or lower.

The last bar groups every scientist with 1,028 publications or more.

Mark Hochstrasser D-index placement in Biology and Biochemistry in 2026

The chart shows the D-index (discipline H-index) distribution of Biology and Biochemistry scientists ranked by Research.com in 2026. The highlighted bar marks where Mark Hochstrasser sits on this spectrum.

40–41 D-Index: 80 scientists 42–43 D-Index: 183 scientists 44–45 D-Index: 316 scientists 46–47 D-Index: 504 scientists 48–49 D-Index: 718 scientists 50–51 D-Index: 899 scientists 52–53 D-Index: 1,025 scientists 54–55 D-Index: 1,149 scientists 56–57 D-Index: 1,235 scientists 58–59 D-Index: 1,253 scientists 60–61 D-Index: 1,162 scientists 62–63 D-Index: 1,130 scientists 64–65 D-Index: 1,031 scientists 66–67 D-Index: 897 scientists 68–69 D-Index: 814 scientists 70–71 D-Index: 714 scientists 72–73 D-Index: 709 scientists 74–75 D-Index: 596 scientists 76–77 D-Index: 512 scientists 78–79 D-Index: 473 scientists 80–81 D-Index: 412 scientists 82–83 D-Index: 373 scientists 84–85 D-Index: 358 scientists 86–87 D-Index: 285 scientists 88–89 D-Index: 273 scientists 90–91 D-Index: 227 scientists 92–93 D-Index: 208 scientists 94–95 D-Index: 193 scientists 96–97 D-Index: 153 scientists 98–99 D-Index: 157 scientists 100–101 D-Index: 148 scientists 102–103 D-Index: 120 scientists 104–105 D-Index: 113 scientists 106–107 D-Index: 100 scientists 108–109 D-Index: 86 scientists 110–111 D-Index: 67 scientists 112–113 D-Index: 71 scientists 114–115 D-Index: 73 scientists 116–117 D-Index: 64 scientists 118–119 D-Index: 53 scientists 120–121 D-Index: 60 scientists 122–123 D-Index: 54 scientists 124–125 D-Index: 43 scientists 126–127 D-Index: 38 scientists 128–129 D-Index: 49 scientists 130–131 D-Index: 26 scientists 132–133 D-Index: 18 scientists 134–135 D-Index: 23 scientists 136–137 D-Index: 32 scientists 138–139 D-Index: 32 scientists 140–141 D-Index: 27 scientists 142–143 D-Index: 19 scientists 144–145 D-Index: 22 scientists 146–147 D-Index: 12 scientists 148–149 D-Index: 16 scientists 150–151 D-Index: 14 scientists 152–153 D-Index: 10 scientists 154–155 D-Index: 13 scientists 156–157 D-Index: 10 scientists 158–159 D-Index: 7 scientists 160–161 D-Index: 9 scientists 162–163 D-Index: 13 scientists 164–165 D-Index: 4 scientists 166 D-Index: 4 scientists 167+ D-Index: 98 scientists
40 D-Index 167+

This scientist: 84 D-Index — 84th percentile

84% of scientists in this discipline score the same or lower.

The last bar groups every scientist with 167 D-Index or more.

Research.com Recognitions

  • 2016 - Fellow of the American Academy of Arts and Sciences
  • 2012 - Fellow of the American Association for the Advancement of Science (AAAS)

Overview

Mark Hochstrasser is affiliated with Yale University in the United States and specializes in the fields of Biochemistry, Genetics, and Molecular Biology. Their research activity is especially concentrated in Molecular Biology and Cell Biology, with additional work in Insect Science, Epidemiology, and Oncology.

The main topics addressed in Hochstrasser's work include:

  • Ubiquitin and proteasome pathways
  • Endoplasmic Reticulum Stress and Disease
  • Autophagy in Disease and Therapy
  • Insect symbiosis and bacterial influences
  • Peptidase Inhibition and Analysis
  • Cellular transport and secretion
  • RNA modifications and cancer

The scientist has published papers primarily in notable venues such as bioRxiv (Cold Spring Harbor Laboratory), Nature Communications, Genetics, Nucleic Acids Research, and Proceedings of the National Academy of Sciences.

Recent publications include:

  • "Histone sumoylation and chromatin dynamics," 2021, Nucleic Acids Research
  • "The Biochemistry of Cytoplasmic Incompatibility Caused by Endosymbiotic Bacteria," 2020, Genes
  • "Histone sumoylation promotes Set3 histone-deacetylase complex-mediated transcriptional regulation," 2020, Nucleic Acids Research
  • "Structural and mechanistic insights into the complexes formed by Wolbachia cytoplasmic incompatibility factors," 2021, Proceedings of the National Academy of Sciences
  • "SUMO and cellular adaptive mechanisms," 2020, Experimental & Molecular Medicine

Frequent collaborators include:

  • Mengwen Zhang
  • Jason M. Berk
  • Jianhui Li
  • Hong-Yeoul Ryu
  • Adrian B. Mehrtash

Throughout their career, Hochstrasser has received recognition such as becoming a Fellow of the American Association for the Advancement of Science (AAAS) in 2012 and a Fellow of the American Academy of Arts and Sciences in 2016.

Best Publications

  • Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition)

    Daniel J. Klionsky;Amal Kamal Abdel-Aziz;Sara Abdelfatah;Mahmoud Abdellatif

  • UBIQUITIN-DEPENDENT PROTEIN DEGRADATION

    Mark Hochstrasser

  • Modification of Proteins by Ubiquitin and Ubiquitin-Like Proteins

    Oliver Kerscher;Rachael Felberbaum;Mark Hochstrasser

  • Quantitative proteomics reveals the function of unconventional ubiquitin chains in proteasomal degradation.

    Ping Xu;Duc M. Duong;Nicholas T. Seyfried;Dongmei Cheng

  • Mechanism and function of deubiquitinating enzymes.

    Alexander Y. Amerik;Mark Hochstrasser

  • Ubiquitin, proteasomes, and the regulation of intracellular protein degradation.

    Mark Hochstrasser

  • Origin and function of ubiquitin-like proteins

    Mark Hochstrasser

  • Diversity of degradation signals in the ubiquitin–proteasome system

    Tommer Ravid;Mark Hochstrasser

  • A new protease required for cell-cycle progression in yeast

    Shyr-Jiann Li;Mark Hochstrasser

  • Function and regulation of SUMO proteases

    Christopher M. Hickey;Nicole R. Wilson;Mark Hochstrasser

  • Substrate Targeting in the Ubiquitin System

    Jeffrey D. Laney;Mark Hochstrasser

  • A conserved ubiquitin ligase of the nuclear envelope/endoplasmic reticulum that functions in both ER-associated and Matα2 repressor degradation

    Robert Swanson;Martin Locher;Mark Hochstrasser

  • Evolution and function of ubiquitin-like protein-conjugation systems

    Mark Hochstrasser

  • Autocatalytic Subunit Processing Couples Active Site Formation in the 20S Proteasome to Completion of Assembly

    Ping Chen;Mark Hochstrasser

  • Multiple ubiquitin-conjugating enzymes participate in the in vivo degradation of the yeast MATα2 repressor

    Ping Chen;Phoebe Johnson;Thomas Sommer;Stefan Jentsch

  • A superfamily of protein tags: ubiquitin, SUMO and related modifiers.

    David C. Schwartz;Mark Hochstrasser

  • The yeast DOA4 gene encodes a deubiquitinating enzyme related to a product of the human tre-2 oncogene

    Feroz R. Papa;Mark Hochstrasser

  • The Yeast ULP2 (SMT4) Gene Encodes a Novel Protease Specific for the Ubiquitin-Like Smt3 Protein

    Shyr-Jiann Li;Mark Hochstrasser

  • Defining the SUMO-modified Proteome by Multiple Approaches in Saccharomyces cerevisiae,

    J. Thomas Hannich;Alaron Lewis;Mary B. Kroetz;Shyr Jiann Li

  • Molecular architecture and assembly of the eukaryotic proteasome.

    Robert J. Tomko;Mark Hochstrasser

Frequent Co-Authors

Alexander Varshavsky
Alexander Varshavsky California Institute of Technology
John W. Sedat
John W. Sedat University of California, San Francisco
Richard D. Vierstra
Richard D. Vierstra Washington University in St. Louis
Daniel Finley
Daniel Finley Harvard University
Junmin Peng
Junmin Peng St. Jude Children's Research Hospital
Dieter H. Wolf
Dieter H. Wolf University of Stuttgart
Thomas Sommer
Thomas Sommer Max Delbrück Center for Molecular Medicine
Yong Xiong
Yong Xiong Yale University
Stefan Jentsch
Stefan Jentsch Max Planck Society
Yosef Gruenbaum
Yosef Gruenbaum Hebrew University of Jerusalem

External Links

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Publications: 70

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Publications: 54

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Publications: 53

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Publications: 53

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Publications: 48

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Publications: 48

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Publications: 47

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