Keith D. Wilkinson

Overview

Best Publications

• The ubiquitin pathway in Parkinson's disease

  Elisabeth Leroy;Rebecca Boyer;Georg Auburger;Barbara Leube

  2099
  Citations

• Regulation and Cellular Roles of Ubiquitin-Specific Deubiquitinating Enzymes

  Francisca E. Reyes-Turcu;Karen H. Ventii;Keith D. Wilkinson

  1557
  Citations

• Microarray Identification of FMRP-Associated Brain mRNAs and Altered mRNA Translational Profiles in Fragile X Syndrome

  Victoria Brown;Victoria Brown;Peng Jin;Peng Jin;Stephanie Ceman;Stephanie Ceman;Jennifer C. Darnell

  1366
  Citations

• The neuron-specific protein PGP 9.5 is a ubiquitin carboxyl-terminal hydrolase

  Keith D. Wilkinson;Keunmyoung Lee;Seema Deshpande;Penelope Duerksen-Hughes

  1061
  Citations

• FMR1 protein: conserved RNP family domains and selective RNA binding

  Claude T. Ashley;Keith D. Wilkinson;Daniel Reines;Stephen T. Warren

  960
  Citations

• BAP1: a novel ubiquitin hydrolase which binds to the BRCA1 RING finger and enhances BRCA1-mediated cell growth suppression

  David E. Jensen;Monja Proctor;Sandra T. Marquis;Heather Perry Gardner

  869
  Citations

• Ubiquitination and deubiquitination: targeting of proteins for degradation by the proteasome.

  Keith D. Wilkinson

  773
  Citations

• Regulation of ubiquitin-dependent processes by deubiquitinating enzymes.

  Keith D. Wilkinson

  768
  Citations

• Molecular discrimination of structurally equivalent Lys 63-linked and linear polyubiquitin chains

  David Komander;David Komander;Francisca Reyes‐Turcu;Julien D F Licchesi;Peter Odenwaelder

  681
  Citations

• Chemistry-Based Functional Proteomics Reveals Novel Members of the Deubiquitinating Enzyme Family

  Anna Borodovsky;Huib Ovaa;Nagamalleswari Kolli;Tudeviin Gan-Erdene

  664
  Citations

• A novel active site-directed probe specific for deubiquitylating enzymes reveals proteasome association of USP14.

  Anna Borodovsky;Benedikt M. Kessler;Rocco Casagrande;Herman S. Overkleeft

  583
  Citations

• The fragile X mental retardation protein inhibits translation via interacting with mRNA.

  Zhenzhong Li;Youyi Zhang;Li Ku;Keith D. Wilkinson

  535
  Citations

• Ubiquitin is the ATP-dependent proteolysis factor I of rabbit reticulocytes.

  K D Wilkinson;M K Urban;A L Haas

  535
  Citations

• Substrate specificity of deubiquitinating enzymes: ubiquitin C-terminal hydrolases.

  Christopher N. Larsen;Bryan A. Krantz;Keith D. Wilkinson

  516
  Citations

• Structure and mechanisms of the proteasome-associated deubiquitinating enzyme USP14

  Min Hu;Pingwei Li;Ling Song;Philip D Jeffrey

  478
  Citations

• Ubiquitin carboxyl-terminal hydrolase (PGP 9.5) is selectively present in ubiquitinated inclusion bodies characteristic of human neurodegenerative diseases.

  J Lowe;H McDermott;M Landon;R J Mayer

  458
  Citations

• BRCA1-Associated Protein-1 Is a Tumor Suppressor that Requires Deubiquitinating Activity and Nuclear Localization

  Karen H. Ventii;Narra S. Devi;Kenneth L. Friedrich;Tatiana A. Chernova

  388
  Citations

• METABOLISM OF THE POLYUBIQUITIN DEGRADATION SIGNAL : STRUCTURE, MECHANISM,AND ROLE OF ISOPEPTIDASE T

  Keith D. Wilkinson;Valery L. Tashayev;Lydia B. O'Connor;Christopher N. Larsen

  378
  Citations

• The ubiquitin binding domain ZnF UBP recognizes the C-terminal diglycine motif of unanchored ubiquitin.

  Francisca E. Reyes-Turcu;John R. Horton;James E. Mullally;Annie Heroux

  374
  Citations

• Familial Parkinson's disease-associated L166P mutation disrupts DJ-1 protein folding and function.

  James A. Olzmann;Keith Brown;Keith D. Wilkinson;Howard D. Rees

  348
  Citations