Parkinson's disease, Genetics, Parkin, Substantia nigra and Internal medicine are his primary areas of study. His Parkinson's disease research is multidisciplinary, incorporating perspectives in Dopaminergic, Neurodegeneration, Neuroscience, Mitochondrion and Degenerative disease. His Genetics study frequently draws parallels with other fields, such as Parkinsonism.
The concepts of his Parkin study are interwoven with issues in Molecular biology, Ubiquitin, Ubiquitin ligase and Cell biology. His Substantia nigra study is concerned with the larger field of Pathology. His work on Endocrinology expands to the thematically related Internal medicine.
His main research concerns Parkinson's disease, Internal medicine, Genetics, Pathology and Parkin. His biological study spans a wide range of topics, including Neuroscience and Degenerative disease. His Internal medicine research integrates issues from Gastroenterology, Endocrinology and Cardiology.
His study looks at the intersection of Genetics and topics like Parkinsonism with Dementia. He interconnects Lewy body, Ubiquitin, Ubiquitin ligase, Molecular biology and Cell biology in the investigation of issues within Parkin. His research in Substantia nigra tackles topics such as MPTP which are related to areas like Pharmacology.
His primary scientific interests are in Parkinson's disease, Genetics, Parkin, Pathology and Internal medicine. His studies deal with areas such as Neuroscience, Pathogenesis and Degenerative disease as well as Parkinson's disease. His Genetics study combines topics in areas such as Disease and Parkinsonism.
The Parkinsonism study which covers Dementia that intersects with Pediatrics. His Parkin study incorporates themes from Ubiquitin, Ubiquitin ligase, Neurodegeneration and Age of onset. His study in Internal medicine is interdisciplinary in nature, drawing from both Gastroenterology, Endocrinology and Cardiology.
His primary areas of investigation include Parkinson's disease, Genetics, Parkin, Pathology and Substantia nigra. His Parkinson's disease research incorporates themes from Cerebral cortex, Neuroscience, Placebo and Adverse effect. His work in Genetics addresses subjects such as Disease, which are connected to disciplines such as Single-nucleotide polymorphism and Allele.
Parkin is a subfield of Internal medicine that Yoshikuni Mizuno studies. His research investigates the connection with Pathology and areas like Proband which intersect with concerns in Exon. The various areas that he examines in his Substantia nigra study include Oxidative stress, Molecular biology, Genetic enhancement and Microglia.
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Mutations in the parkin gene cause autosomal recessive juvenile parkinsonism
Tohru Kitada;Shuichi Asakawa;Nobutaka Hattori;Hiroto Matsumine.
Diagnosis and management of dementia with Lewy bodies: Third report of the DLB Consortium
I. G. McKeith;I. G. McKeith;D. W. Dickson;J. Lowe;M. Emre.
Familial Parkinson disease gene product, parkin, is a ubiquitin-protein ligase
Hideki Shimura;Nobutaka Hattori;Shin-ichiro Kubo;Yoshikuni Mizuno.
Nature Genetics (2000)
Immunohistochemical detection of 4-hydroxynonenal protein adducts in Parkinson disease.
Asako Yoritaka;Nobutaka Hattori;Koji Uchida;Masashi Tanaka.
Proceedings of the National Academy of Sciences of the United States of America (1996)
Ubiquitination of a New Form of α-Synuclein by Parkin from Human Brain: Implications for Parkinson's Disease
Hideki Shimura;Michael G. Schlossmacher;Nobutaka Hattori;Matthew P. Frosch.
An Unfolded Putative Transmembrane Polypeptide, which Can Lead to Endoplasmic Reticulum Stress, Is a Substrate of Parkin
Yuzuru Imai;Mariko Soda;Haruhisa Inoue;Nobutaka Hattori.
Diagnostic procedures for Parkinson's disease dementia: Recommendations from the movement disorder society task force
Bruno Dubois;David Burn;Christopher Goetz;Dag Aarsland;Dag Aarsland.
Movement Disorders (2007)
Protein-bound acrolein: Potential markers for oxidative stress
Koji Uchida;Masamichi Kanematsu;Kensuke Sakai;Tsukasa Matsuda.
Proceedings of the National Academy of Sciences of the United States of America (1998)
Structural Dimorphism in the Mitochondrial Targeting Sequence in the Human Manganese Superoxide Dismutase Gene: A Predictive Evidence for Conformational Change to Influence Mitochondrial Transport and a Study of Allelic Association in Parkinson's Disease
Satoe Shimoda-Matsubayashi;Hiroto Matsumine;Tomonori Kobayashi;Yuko Nakagawa-Hattori.
Biochemical and Biophysical Research Communications (1996)
Histochemical detection of apoptosis in Parkinson's disease.
Hideki Mochizuki;Keigo Goto;Hideo Mori;Yoshikuni Mizuno.
Journal of the Neurological Sciences (1996)
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