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Nobutaka Hattori

Nobutaka Hattori

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Biology and Biochemistry
Japan
2023

D-Index & Metrics

Medicine

D-Index
115
Citations
72225
World Ranking
4442
National Ranking
95

Research.com Recognitions

  • 2023 - Research.com Biology and Biochemistry in Japan Leader Award

Overview

Nobutaka Hattori is affiliated with Juntendo University in Japan and has contributed extensively to the field of medicine, with a primary focus on neurology and related disciplines. Their research encompasses a range of subfields including molecular biology, physiology, cellular and molecular neuroscience, and epidemiology.

Their work addresses key topics such as Parkinson's disease mechanisms and treatments, neurological disorders and treatments, neurological diseases and metabolism, RNA regulation and disease, botulinum toxin and related neurological disorders, autophagy in disease and therapy, and advanced neuroimaging techniques and applications.

Notable recent publications include:

  • Propagative α-synuclein seeds as serum biomarkers for synucleinopathies, 2023, Nature Medicine
  • Levodopa Dose Equivalency in Parkinson's Disease: Updated Systematic Review and Proposals, 2023, Movement Disorders
  • Molecular genetics of Parkinson's disease: Contributions and global trends, 2022, Journal of Human Genetics
  • The effects of A1/A2 astrocytes on oligodendrocyte linage cells against white matter injury under prolonged cerebral hypoperfusion, 2020, Glia
  • Variants in saposin D domain of prosaposin gene linked to Parkinson's disease, 2020, Brain

Frequent collaborators include:

  • Taku Hatano
  • Genko Oyama
  • Kenya Nishioka
  • Koji Kamagata
  • Shigeki Aoki

Their publications are predominantly featured in journals such as:

  • Movement Disorders Clinical Practice
  • Parkinsonism & Related Disorders
  • Movement Disorders
  • bioRxiv (Cold Spring Harbor Laboratory)
  • Scientific Reports

Best Publications

  • Mutations in the parkin gene cause autosomal recessive juvenile parkinsonism

    Tohru Kitada;Shuichi Asakawa;Nobutaka Hattori;Hiroto Matsumine

  • Familial Parkinson disease gene product, parkin, is a ubiquitin-protein ligase

    Hideki Shimura;Nobutaka Hattori;Shin-ichiro Kubo;Yoshikuni Mizuno

  • PINK1 stabilized by mitochondrial depolarization recruits Parkin to damaged mitochondria and activates latent Parkin for mitophagy

    Noriyuki Matsuda;Shigeto Sato;Kahori Shiba;Kei Okatsu

  • Genome-wide association study identifies common variants at four loci as genetic risk factors for Parkinson's disease

    Wataru Satake;Yuko Nakabayashi;Yuko Nakabayashi;Ikuko Mizuta;Ikuko Mizuta;Yushi Hirota;Yushi Hirota

  • Immunohistochemical detection of 4-hydroxynonenal protein adducts in Parkinson disease.

    Asako Yoritaka;Nobutaka Hattori;Koji Uchida;Masashi Tanaka

  • Ubiquitination of a New Form of α-Synuclein by Parkin from Human Brain: Implications for Parkinson's Disease

    Hideki Shimura;Michael G. Schlossmacher;Nobutaka Hattori;Matthew P. Frosch

  • An Unfolded Putative Transmembrane Polypeptide, which Can Lead to Endoplasmic Reticulum Stress, Is a Substrate of Parkin

    Yuzuru Imai;Mariko Soda;Haruhisa Inoue;Nobutaka Hattori

  • Protein-bound acrolein: Potential markers for oxidative stress

    Koji Uchida;Masamichi Kanematsu;Kensuke Sakai;Tsukasa Matsuda

  • Mitochondrial Electron Transport Complex I Is a Potential Source of Oxygen Free Radicals in the Failing Myocardium

    Tomomi Ide;Hiroyuki Tsutsui;Shintaro Kinugawa;Hideo Utsumi

  • A rotarod test for evaluation of motor skill learning.

    Hiromi Shiotsuki;Kenji Yoshimi;Yasushi Shimo;Manabu Funayama

  • Mitochondrial Genome Variation in Eastern Asia and the Peopling of Japan

    Masashi Tanaka;Vicente M. Cabrera;Ana M. González;José M. Larruga

  • Collaborative analysis of alpha-synuclein gene promoter variability and Parkinson disease.

    Demetrius M. Maraganore;Mariza De Andrade;Alexis Elbaz;Matthew J. Farrer

  • PINK1-mediated phosphorylation of the Parkin ubiquitin-like domain primes mitochondrial translocation of Parkin and regulates mitophagy

    Kahori Shiba-Fukushima;Yuzuru Imai;Shigeharu Yoshida;Yasushi Ishihama

  • Methylglyoxal Modification of Protein: CHEMICAL AND IMMUNOCHEMICAL CHARACTERIZATION OF METHYLGLYOXAL-ARGININE ADDUCTS *

    Tomoko Oya;Nobutaka Hattori;Yoshikuni Mizuno;Satoshi Miyata

  • PINK1 autophosphorylation upon membrane potential dissipation is essential for Parkin recruitment to damaged mitochondria.

    Kei Okatsu;Toshihiko Oka;Masahiro Iguchi;Kenji Imamura;Kenji Imamura

  • p62/SQSTM1 cooperates with Parkin for perinuclear clustering of depolarized mitochondria

    Kei Okatsu;Keiko Saisho;Midori Shimanuki;Kazuto Nakada

  • Caffeine induces apoptosis by enhancement of autophagy via PI3K/Akt/mTOR/p70S6K inhibition

    Shinji Saiki;Yukiko Sasazawa;Yoko Imamichi;Sumihiro Kawajiri

  • Mutations in COQ2 in familial and sporadic multiple-system atrophy the multiple-system atrophy research collaboration

    Jun Mitsui;Takashi Matsukawa;Hiroyuki Ishiura;Yoko Fukuda;Yoko Fukuda

  • Molecular genetic analysis of a novel Parkin gene in Japanese families with autosomal recessive juvenile parkinsonism: evidence for variable homozygous deletions in the Parkin gene in affected individuals.

    Nobutaka Hattori;Tohru Kitada;Tohru Kitada;Hiroto Matsumine;Shuichi Asakawa

  • Etiology and Pathogenesis of Parkinson’s Disease

    Taku Hatano;Nobutaka Hattori

Frequent Co-Authors

Yoshikuni Mizuno
Yoshikuni Mizuno Juntendo University
Hideki Mochizuki
Hideki Mochizuki Osaka University
Tatsushi Toda
Tatsushi Toda University of Tokyo
Matthew J. Farrer
Matthew J. Farrer University of Florida
Gen Sobue
Gen Sobue Aichi Medical University
Ryosuke Takahashi
Ryosuke Takahashi Kyoto University
Keiji Tanaka
Keiji Tanaka Tokyo Metropolitan Institute of Medical Science
Akio Mori
Akio Mori University of Tokyo
Hideyuki Okano
Hideyuki Okano Keio University
Koichi Ishiguro
Koichi Ishiguro Juntendo University

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