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Hideki Mochizuki

Hideki Mochizuki

D-Index & Metrics

Neuroscience

D-Index
83
Citations
22463
World Ranking
1467
National Ranking
30

Overview

Hideki Mochizuki is a researcher affiliated with Osaka University in Japan. Their research primarily focuses on the field of medicine, with an emphasis on neurology. They have contributed extensively to subfields such as neurology, molecular biology, epidemiology, cellular and molecular neuroscience, and physiology.

Their scientific work covers main topics including:

  • Parkinson's Disease Mechanisms and Treatments
  • Neurological disorders and treatments
  • Alzheimer's disease research and treatments
  • Acute Ischemic Stroke Management
  • Amyotrophic Lateral Sclerosis Research
  • Genetic Neurodegenerative Diseases
  • Neurogenetic and Muscular Disorders Research

Among their recent publications are:

  • A slipped-CAG DNA-binding small molecule induces trinucleotide-repeat contractions in vivo, 2020, Nature Genetics
  • Parkinson's disease and iron, 2020, Journal of Neural Transmission
  • Alternative mitochondrial quality control mediated by extracellular release, 2020, Autophagy
  • Whole gut virome analysis of 476 Japanese revealed a link between phage and autoimmune disease, 2021, Annals of the Rheumatic Diseases
  • Comparison of serum and plasma as a source of blood extracellular vesicles: Increased levels of platelet-derived particles in serum extracellular vesicle fractions alter content profiles from plasma extracellular vesicle fractions, 2022, PLoS ONE

Frequent co-authors in Hideki Mochizuki's collaborations include:

  • Tsutomu Sasaki
  • Kensuke Ikenaka
  • Yasufumi Gon
  • Tatsusada Okuno
  • Kenichi Todo

The researcher's publications have appeared in venues such as:

  • bioRxiv (Cold Spring Harbor Laboratory)
  • Rinsho Shinkeigaku
  • Scientific Reports
  • Internal Medicine
  • Movement Disorders

Hideki Mochizuki's body of work encompasses 422 publications in medicine, with many contributions focusing on neurological conditions and molecular studies related to neurodegenerative diseases and treatment approaches. The topics reflect a blend of clinical and molecular research aimed at understanding disease mechanisms and exploring potential therapeutic avenues within neurology and related biomedical sciences.

Best Publications

  • Histochemical detection of apoptosis in Parkinson's disease.

    Hideki Mochizuki;Keigo Goto;Hideo Mori;Yoshikuni Mizuno

  • Mitochondrial dysfunction associated with increased oxidative stress and α-synuclein accumulation in PARK2 iPSC-derived neurons and postmortem brain tissue.

    Yoichi Imaizumi;Yohei Okada;Wado Akamatsu;Masato Koike

  • Overexpression of alpha-synuclein in rat substantia nigra results in loss of dopaminergic neurons, phosphorylation of alpha-synuclein and activation of caspase-9: resemblance to pathogenetic changes in Parkinson's disease.

    Masanori Yamada;Takeshi Iwatsubo;Yoshikuni Mizuno;Hideki Mochizuki

  • Specific brain processing of facial expressions in people with alexithymia: an H215O‐PET study

    Michiko Kano;Shin Fukudo;Jiro Gyoba;Miyuki Kamachi

  • Maternal obesity impairs hippocampal BDNF production and spatial learning performance in young mouse offspring.

    Yusuke Tozuka;Mami Kumon;Etsuko Wada;Masafumi Onodera

  • Migration of enhanced green fluorescent protein expressing bone marrow-derived microglia/macrophage into the mouse brain following permanent focal ischemia

    R Tanaka;M Komine-Kobayashi;H Mochizuki;M Yamada

  • Little evidence of transdifferentiation of bone marrow-derived cells into pancreatic beta cells

    J. B. Choi;H. Uchino;K. Azuma;N. Iwashita

  • A three-dimensional single-cell-resolution whole-brain atlas using CUBIC-X expansion microscopy and tissue clearing

    Tatsuya C. Murakami;Tomoyuki Mano;Shu Saikawa;Shuhei A. Horiguchi;Shuhei A. Horiguchi

  • Neuroprotective effect of recombinant human granulocyte colony-stimulating factor in transient focal ischemia of mice.

    Miki Komine-Kobayashi;Ning Zhang;Meizi Liu;Ryota Tanaka

  • Imaging of central itch modulation in the human brain using positron emission tomography.

    Hideki Mochizuki;Manabu Tashiro;Michiko Kano;Yumiko Sakurada

  • Role of mitochondria in the etiology and pathogenesis of Parkinson's disease.

    Yoshikuni Mizuno;Shin-ichirou Ikebe;Nobutaka Hattori;Yuko Nakagawa-Hattori

  • An AAV-derived Apaf-1 dominant negative inhibitor prevents MPTP toxicity as antiapoptotic gene therapy for Parkinson's disease

    Hideki Mochizuki;Hideki Hayakawa;Makoto Migita;Mamoru Shibata

  • Roles of histamine in regulation of arousal and cognition : functional neuroimaging of histamine H1 receptors in human brain

    Manabu Tashiro;Hideki Mochizuki;Kentaro Iwabuchi;Yumiko Sakurada

  • Splicing misregulation of SCN5A contributes to cardiac-conduction delay and heart arrhythmia in myotonic dystrophy

    Fernande Freyermuth;Frédérique Rau;Yosuke Kokunai;Thomas Linke

  • Dopaminergic neurons degenerate by apoptosis in Parkinson's disease.

    Etienne C. Hirsch;Stéphane Hunot;Baptiste Faucheux;Yves Agid

  • Apoptosis is induced by 1-methyl-4-phenylpyridinium ion (MPP+) in ventral mesencephalic-striatal co-culture in rat

    Hideki Mochizuki;Noriyuki Nakamura;Katsunori Nishi;Yoshikuni Mizuno

  • Caspase-11 Mediates Inflammatory Dopaminergic Cell Death in the 1-Methyl-4-Phenyl-1,2,3,6-Tetrahydropyridine Mouse Model of Parkinson's Disease

    Tsuyoshi Furuya;Hideki Hayakawa;Masanori Yamada;Kenji Yoshimi

  • Iron accumulation in the substantia nigra of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP)-induced hemiparkinsonian monkeys

    Hideki Mochizuki;Hisamasa Imai;Kiyonori Endo;Kazuko Yokomizo

  • Central Effects of Fexofenadine and Cetirizine: Measurement of Psychomotor Performance, Subjective Sleepiness, and Brain Histamine H1-Receptor Occupancy Using 11C-Doxepin Positron Emission Tomography

    Manabu Tashiro;Yumiko Sakurada;Kentaro Iwabuchi;Hideki Mochizuki

  • Possibility for neurogenesis in substantia nigra of parkinsonian brain

    Kenji Yoshimi;Yong Ri Ren;Tatsunori Seki;Masanori Yamada

Frequent Co-Authors

Haruhiko Kishima
Haruhiko Kishima Osaka University
Kazuhiko Yanai
Kazuhiko Yanai Tohoku University
Manabu Tashiro
Manabu Tashiro Tohoku University
Toshihide Yamashita
Toshihide Yamashita Osaka University
Tatsunori Seki
Tatsunori Seki Tokyo Medical University
Gen Sobue
Gen Sobue Aichi Medical University
Masayuki Hirata
Masayuki Hirata Osaka University
Yukinori Okada
Yukinori Okada Osaka University
Takanori Yokota
Takanori Yokota Institute of Science Tokyo
Tatsushi Toda
Tatsushi Toda University of Tokyo

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