Toshiharu Nagatsu

Overview

Best Publications

• TYROSINE HYDROXYLASE. THE INITIAL STEP IN NOREPINEPHRINE BIOSYNTHESIS.

  Toshiharu Nagatsu;Morton Levitt;Sidney Udenfriend

  2698
  Citations

• Tumor necrosis factor-α (TNF-α) increases both in the brain and in the cerebrospinal fluid from parkinsonian patients

  Makio Mogi;Minoru Harada;Peter Riederer;Hirotaro Narabayashi

  1165
  Citations

• Interleukin-1β, interleukin-6, epidermal growth factor and transforming growth factor-α are elevated in the brain from parkinsonian patients

  Makio Mogi;Minoru Harada;Tomoyshi Kondo;Peter Riederer

  996
  Citations

• Hereditary progressive dystonia with marked diurnal fluctuation caused by mutations in the GTP cyclohydrolase I gene

  Hiroshi Ichinose;Tamae Ohye;Ei ichi Takahashi;Ei ichi Takahashi;Naohiko Seki

  941
  Citations

• Distribution of major histocompatibility complex class II-positive microglia and cytokine profile of Parkinson's disease brains

  Kazuhiro Imamura;Nozomi Hishikawa;Makoto Sawada;Toshiharu Nagatsu

  775
  Citations

• Changes in cytokines and neurotrophins in Parkinson's disease.

  T Nagatsu;M Mogi;H Ichinose;A Togari

  658
  Citations

• Photometric Assay of Dopamine-β-Hydroxylase Activity in Human Blood

  Toshiharu Nagatsu;Sidney Udenfriend

  656
  Citations

• Interleukin (IL)-1β, IL-2, IL-4, IL-6 and transforming growth factor-α levels are elevated in ventricular cerebrospinal fluid in juvenile parkinsonism and Parkinson's disease

  Makio Mogi;Minoru Harada;Hirotaro Narabayashi;Hirofumi Inagaki

  643
  Citations

• The newly synthesized selective Ca2+calmodulin dependent protein kinase II inhibitor KN-93 reduces dopamine contents in PC12h cells

  Mariko Sumi;Kazutoshi Kiuchi;Tomohiko Ishikawa;Akira Ishii

  611
  Citations

• Inflammatory process in Parkinson's disease: role for cytokines.

  T Nagatsu;M Sawada

  497
  Citations

• Expanded polyglutamine stretches interact with TAFII130, interfering with CREB-dependent transcription.

  Takayoshi Shimohata;Toshihiro Nakajima;Mitsunori Yamada;Chiharu Uchida

  491
  Citations

• Brain-derived growth factor and nerve growth factor concentrations are decreased in the substantia nigra in Parkinson's disease.

  Makio Mogi;Akifumi Togari;Tomoyoshi Kondo;Yoshikuni Mizuno

  491
  Citations

• Inhibitors of purified beef adrenal tyrosine hydroxylase.

  Sidney Udenfriend;P. Zaltzman-Nirenberg;T. Nagatsu

  427
  Citations

• Role of cytokines in inflammatory process in Parkinson’s disease

  M. Sawada;K. Imamura;T. Nagatsu;T. Nagatsu

  416
  Citations

• Cytokines in Parkinson’s Disease

  T. Nagatsu;M. Mogi;H. Ichinose;A. Togari

  393
  Citations

• New chromogenic substrates for X-prolyl dipeptidyl-aminopeptidase.

  Toshiharu Nagatsu;Masami Hino;Hiroshi Fuyamada;Taro Hayakawa

  386
  Citations

• Neuroprotective effects of glial cell line-derived neurotrophic factor mediated by an adeno-associated virus vector in a transgenic animal model of amyotrophic lateral sclerosis.

  Li-Jun Wang;Yan-Yan Lu;Shin-ichi Muramatsu;Kunihiko Ikeguchi

  360
  Citations

• Caspase activities and tumor necrosis factor receptor R1 (p55) level are elevated in the substantia nigra from parkinsonian brain.

  M. Mogi;A. Togari;T. Kondo;Y. Mizuno

  348
  Citations

• A quantitative-trait analysis of human plasma-dopamine β-hydroxylase activity: Evidence for a major functional polymorphism at the DBH locus

  Cyrus P. Zabetian;George M. Anderson;Sarah G. Buxbaum;Robert C. Elston

  347
  Citations

• Highly sensitive assay for tyrosine hydroxylase activity by high-performance liquid chromatography

  Toshiharu Nagatsu;Kazuhiro Oka;Takeshi Kato

  342
  Citations