World's Best Scientists 2026 revealed!
Toshiharu Nagatsu

Toshiharu Nagatsu

D-Index & Metrics

Medicine

D-Index
108
Citations
45772
World Ranking
5976
National Ranking
132

Toshiharu Nagatsu publication distribution in Medicine in 2026

The chart shows the distribution of publications by all Research.com ranked scientists in the field of Medicine in 2026. The highlighted bar marks where Toshiharu Nagatsu sits on this spectrum.

101–120 publications: 5 scientists 121–140 publications: 26 scientists 141–160 publications: 73 scientists 161–180 publications: 155 scientists 181–200 publications: 230 scientists 201–220 publications: 363 scientists 221–240 publications: 487 scientists 241–260 publications: 545 scientists 261–280 publications: 722 scientists 281–300 publications: 768 scientists 301–320 publications: 834 scientists 321–340 publications: 895 scientists 341–360 publications: 922 scientists 361–380 publications: 838 scientists 381–400 publications: 861 scientists 401–420 publications: 918 scientists 421–440 publications: 806 scientists 441–460 publications: 771 scientists 461–480 publications: 751 scientists 481–500 publications: 713 scientists 501–520 publications: 617 scientists 521–540 publications: 611 scientists 541–560 publications: 537 scientists 561–580 publications: 504 scientists 581–600 publications: 509 scientists 601–620 publications: 396 scientists 621–640 publications: 386 scientists 641–660 publications: 371 scientists 661–680 publications: 340 scientists 681–700 publications: 336 scientists 701–720 publications: 307 scientists 721–740 publications: 259 scientists 741–760 publications: 230 scientists 761–780 publications: 228 scientists 781–800 publications: 217 scientists 801–820 publications: 204 scientists 821–840 publications: 186 scientists 841–860 publications: 177 scientists 861–880 publications: 155 scientists 881–900 publications: 139 scientists 901–920 publications: 145 scientists 921–940 publications: 116 scientists 941–960 publications: 133 scientists 961–980 publications: 91 scientists 981–1,000 publications: 96 scientists 1,001–1,020 publications: 77 scientists 1,021–1,040 publications: 70 scientists 1,041–1,060 publications: 63 scientists 1,061–1,080 publications: 77 scientists 1,081–1,100 publications: 49 scientists 1,101–1,120 publications: 54 scientists 1,121–1,140 publications: 49 scientists 1,141–1,160 publications: 51 scientists 1,161–1,180 publications: 35 scientists 1,181–1,200 publications: 39 scientists 1,201–1,220 publications: 26 scientists 1,221–1,240 publications: 37 scientists 1,241–1,260 publications: 36 scientists 1,261–1,280 publications: 27 scientists 1,281–1,300 publications: 32 scientists 1,301–1,320 publications: 28 scientists 1,321–1,340 publications: 17 scientists 1,341–1,360 publications: 30 scientists 1,361–1,380 publications: 28 scientists 1,381–1,400 publications: 17 scientists 1,401–1,420 publications: 21 scientists 1,421–1,440 publications: 15 scientists 1,441–1,460 publications: 12 scientists 1,461–1,480 publications: 12 scientists 1,481–1,500 publications: 18 scientists 1,501–1,520 publications: 14 scientists 1,521–1,540 publications: 17 scientists 1,541–1,560 publications: 15 scientists 1,561–1,580 publications: 6 scientists 1,581–1,600 publications: 2 scientists 1,601–1,620 publications: 12 scientists 1,621–1,640 publications: 11 scientists 1,641–1,660 publications: 8 scientists 1,661–1,680 publications: 5 scientists 1,681–1,700 publications: 5 scientists 1,701–1,720 publications: 10 scientists 1,721–1,740 publications: 12 scientists 1,741–1,760 publications: 14 scientists 1,761–1,780 publications: 6 scientists 1,781–1,795 publications: 5 scientists 1,796+ publications: 100 scientists
101 publications 1,796+

This scientist: 933 publications — 92nd percentile

92% of scientists in this discipline score the same or lower.

The last bar groups every scientist with 1,796 publications or more.

Toshiharu Nagatsu D-index placement in Medicine in 2026

The chart shows the D-index (discipline H-index) distribution of Medicine scientists ranked by Research.com in 2026. The highlighted bar marks where Toshiharu Nagatsu sits on this spectrum.

70–71 D-Index: 226 scientists 72–73 D-Index: 391 scientists 74–75 D-Index: 574 scientists 76–77 D-Index: 730 scientists 78–79 D-Index: 891 scientists 80–81 D-Index: 972 scientists 82–83 D-Index: 1,027 scientists 84–85 D-Index: 1,003 scientists 86–87 D-Index: 960 scientists 88–89 D-Index: 970 scientists 90–91 D-Index: 922 scientists 92–93 D-Index: 839 scientists 94–95 D-Index: 808 scientists 96–97 D-Index: 779 scientists 98–99 D-Index: 668 scientists 100–101 D-Index: 611 scientists 102–103 D-Index: 630 scientists 104–105 D-Index: 513 scientists 106–107 D-Index: 541 scientists 108–109 D-Index: 445 scientists 110–111 D-Index: 429 scientists 112–113 D-Index: 400 scientists 114–115 D-Index: 393 scientists 116–117 D-Index: 318 scientists 118–119 D-Index: 302 scientists 120–121 D-Index: 287 scientists 122–123 D-Index: 255 scientists 124–125 D-Index: 256 scientists 126–127 D-Index: 252 scientists 128–129 D-Index: 230 scientists 130–131 D-Index: 179 scientists 132–133 D-Index: 168 scientists 134–135 D-Index: 163 scientists 136–137 D-Index: 159 scientists 138–139 D-Index: 134 scientists 140–141 D-Index: 134 scientists 142–143 D-Index: 118 scientists 144–145 D-Index: 109 scientists 146–147 D-Index: 106 scientists 148–149 D-Index: 74 scientists 150–151 D-Index: 79 scientists 152–153 D-Index: 80 scientists 154–155 D-Index: 87 scientists 156–157 D-Index: 57 scientists 158–159 D-Index: 74 scientists 160–161 D-Index: 69 scientists 162–163 D-Index: 60 scientists 164–165 D-Index: 53 scientists 166–167 D-Index: 39 scientists 168–169 D-Index: 42 scientists 170–171 D-Index: 32 scientists 172–173 D-Index: 39 scientists 174–175 D-Index: 40 scientists 176–177 D-Index: 28 scientists 178–179 D-Index: 19 scientists 180–181 D-Index: 23 scientists 182–183 D-Index: 31 scientists 184–185 D-Index: 18 scientists 186–187 D-Index: 20 scientists 188–189 D-Index: 22 scientists 190–191 D-Index: 13 scientists 192–193 D-Index: 21 scientists 194–195 D-Index: 12 scientists 196–197 D-Index: 12 scientists 198–199 D-Index: 14 scientists 200–201 D-Index: 15 scientists 202–203 D-Index: 13 scientists 204–205 D-Index: 10 scientists 206–207 D-Index: 8 scientists 208–209 D-Index: 4 scientists 210–211 D-Index: 12 scientists 212–213 D-Index: 11 scientists 214–215 D-Index: 10 scientists 216 D-Index: 4 scientists 217+ D-Index: 98 scientists
70 D-Index 217+

This scientist: 108 D-Index — 71st percentile

71% of scientists in this discipline score the same or lower.

The last bar groups every scientist with 217 D-Index or more.

Overview

Toshiharu Nagatsu is affiliated with Fujita Health University in Japan. Their research primarily focuses on the fields of biochemistry, genetics, molecular biology, and medicine, with specific work spanning neurology, molecular biology, cell biology, cellular and molecular neuroscience, and clinical biochemistry.

The scientist's main topics of study include:

  • Parkinson's Disease Mechanisms and Treatments
  • RNA regulation and disease
  • Melanin and skin pigmentation
  • Nuclear Receptors and Signaling
  • Metabolism and Genetic Disorders
  • Ginkgo biloba and Cashew Applications
  • Retinoids in leukemia and cellular processes

Toshiharu Nagatsu has published extensively in several academic journals. The most frequent publication venues are:

  • Journal of Neural Transmission
  • International Journal of Molecular Sciences
  • Preprints.org
  • The Journal of Biochemistry
  • PubMed

Notable recent papers by Toshiharu Nagatsu include:

  • Neuromelanin in Parkinson's Disease: Tyrosine Hydroxylase and Tyrosinase, 2022, International Journal of Molecular Sciences
  • The role of tyrosine hydroxylase as a key player in neuromelanin synthesis and the association of neuromelanin with Parkinson's disease, 2023, Journal of Neural Transmission
  • Neuromelanin in Parkinson's Disease: Tyrosine Hydroxylase and Tyrosinase, 2022, Preprints.org
  • Catecholamines and Parkinson's disease: tyrosine hydroxylase (TH) over tetrahydrobiopterin (BH4) and GTP cyclohydrolase I (GCH1) to cytokines, neuromelanin, and gene therapy: a historical overview, 2023, Journal of Neural Transmission

Coauthors frequently collaborating with Toshiharu Nagatsu include:

  • Johannes M. Dijkstra
  • Hirohisa Watanabe
  • Akira Nakashima
  • Shosuke Ito
  • Kazumasa Wakamatsu

Best Publications

  • TYROSINE HYDROXYLASE. THE INITIAL STEP IN NOREPINEPHRINE BIOSYNTHESIS.

    Toshiharu Nagatsu;Morton Levitt;Sidney Udenfriend

  • Tumor necrosis factor-α (TNF-α) increases both in the brain and in the cerebrospinal fluid from parkinsonian patients

    Makio Mogi;Minoru Harada;Peter Riederer;Hirotaro Narabayashi

  • Interleukin-1β, interleukin-6, epidermal growth factor and transforming growth factor-α are elevated in the brain from parkinsonian patients

    Makio Mogi;Minoru Harada;Tomoyshi Kondo;Peter Riederer

  • Hereditary progressive dystonia with marked diurnal fluctuation caused by mutations in the GTP cyclohydrolase I gene

    Hiroshi Ichinose;Tamae Ohye;Ei ichi Takahashi;Ei ichi Takahashi;Naohiko Seki

  • Distribution of major histocompatibility complex class II-positive microglia and cytokine profile of Parkinson's disease brains

    Kazuhiro Imamura;Nozomi Hishikawa;Makoto Sawada;Toshiharu Nagatsu

  • Changes in cytokines and neurotrophins in Parkinson's disease.

    T Nagatsu;M Mogi;H Ichinose;A Togari

  • Photometric Assay of Dopamine-β-Hydroxylase Activity in Human Blood

    Toshiharu Nagatsu;Sidney Udenfriend

  • Interleukin (IL)-1β, IL-2, IL-4, IL-6 and transforming growth factor-α levels are elevated in ventricular cerebrospinal fluid in juvenile parkinsonism and Parkinson's disease

    Makio Mogi;Minoru Harada;Hirotaro Narabayashi;Hirofumi Inagaki

  • The newly synthesized selective Ca2+calmodulin dependent protein kinase II inhibitor KN-93 reduces dopamine contents in PC12h cells

    Mariko Sumi;Kazutoshi Kiuchi;Tomohiko Ishikawa;Akira Ishii

  • Inflammatory process in Parkinson's disease: role for cytokines.

    T Nagatsu;M Sawada

  • Expanded polyglutamine stretches interact with TAFII130, interfering with CREB-dependent transcription.

    Takayoshi Shimohata;Toshihiro Nakajima;Mitsunori Yamada;Chiharu Uchida

  • Brain-derived growth factor and nerve growth factor concentrations are decreased in the substantia nigra in Parkinson's disease.

    Makio Mogi;Akifumi Togari;Tomoyoshi Kondo;Yoshikuni Mizuno

  • Inhibitors of purified beef adrenal tyrosine hydroxylase.

    Sidney Udenfriend;P. Zaltzman-Nirenberg;T. Nagatsu

  • Role of cytokines in inflammatory process in Parkinson’s disease

    M. Sawada;K. Imamura;T. Nagatsu;T. Nagatsu

  • Cytokines in Parkinson’s Disease

    T. Nagatsu;M. Mogi;H. Ichinose;A. Togari

  • New chromogenic substrates for X-prolyl dipeptidyl-aminopeptidase.

    Toshiharu Nagatsu;Masami Hino;Hiroshi Fuyamada;Taro Hayakawa

  • Neuroprotective effects of glial cell line-derived neurotrophic factor mediated by an adeno-associated virus vector in a transgenic animal model of amyotrophic lateral sclerosis.

    Li-Jun Wang;Yan-Yan Lu;Shin-ichi Muramatsu;Kunihiko Ikeguchi

  • Caspase activities and tumor necrosis factor receptor R1 (p55) level are elevated in the substantia nigra from parkinsonian brain.

    M. Mogi;A. Togari;T. Kondo;Y. Mizuno

  • A quantitative-trait analysis of human plasma-dopamine β-hydroxylase activity: Evidence for a major functional polymorphism at the DBH locus

    Cyrus P. Zabetian;George M. Anderson;Sarah G. Buxbaum;Robert C. Elston

  • Highly sensitive assay for tyrosine hydroxylase activity by high-performance liquid chromatography

    Toshiharu Nagatsu;Kazuhiro Oka;Takeshi Kato

Frequent Co-Authors

Hiroshi Ichinose
Hiroshi Ichinose Tokyo Institute of Technology
Ikuko Nagatsu
Ikuko Nagatsu Fujita Health University
Makoto Naoi
Makoto Naoi Nagoya Institute of Technology
Kazuto Kobayashi
Kazuto Kobayashi Fukushima Medical University
Hiroyoshi Hidaka
Hiroyoshi Hidaka D. Western Therapeutics Institute (Japan)
Hamao Umezawa
Hamao Umezawa National Institutes of Health
Norio Ozaki
Norio Ozaki Nagoya University
Kunio Yagi
Kunio Yagi Nagoya University
Tomio Takeuchi
Tomio Takeuchi Keio University
Yoshikuni Mizuno
Yoshikuni Mizuno Juntendo University

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