His scientific interests lie mostly in Internal medicine, Endocrinology, Dipeptidyl peptidase, Biochemistry and Immunology. His Internal medicine study combines topics from a wide range of disciplines, such as Kynurenine pathway and Kynurenine. His work carried out in the field of Endocrinology brings together such families of science as Tryptophan, Immune system and Serotonin.
His Dipeptidyl peptidase research incorporates themes from Vildagliptin, Protease, Antigen, In vivo and Dipeptidyl peptidase-4. His research in Biochemistry tackles topics such as Molecular biology which are related to areas like CCL20, CCL15, CCL13 and CXCL2. The Haptoglobin study which covers Acute-phase protein that intersects with Alpha.
Simon Scharpé spends much of his time researching Internal medicine, Endocrinology, Biochemistry, Dipeptidyl peptidase and Enzyme. His research in Internal medicine intersects with topics in Immunology and Prolyl endopeptidase. His Endocrinology study integrates concerns from other disciplines, such as Tryptophan, Immune system, Acute-phase protein and Serotonin.
In his study, Chemokine is inextricably linked to Molecular biology, which falls within the broad field of Biochemistry. He has included themes like Dipeptide, Serine, In vivo and Dipeptidyl peptidase-4 in his Dipeptidyl peptidase study. His Enzyme research is multidisciplinary, incorporating perspectives in Chromatography, Angiotensin-converting enzyme and Stereochemistry.
His primary areas of investigation include Internal medicine, Endocrinology, Biochemistry, Dipeptidyl peptidase and Dipeptidyl peptidase-4. He performs integrative study on Internal medicine and Placebo. His Endocrinology research incorporates elements of Kynurenic acid, Vasoactive intestinal peptide and Neuroprotection.
His Dipeptidyl peptidase study incorporates themes from Immunohistochemistry, Vildagliptin, Molecular mass, Molecular biology and Pharmacology. The Dipeptidyl peptidase-4 study combines topics in areas such as U937 cell, Recombinant DNA, Size-exclusion chromatography, Gene silencing and In vivo. His study looks at the relationship between Enzyme and fields such as Dipeptidyl peptidase 8, as well as how they intersect with chemical problems.
Simon Scharpé mainly focuses on Internal medicine, Endocrinology, Biochemistry, Dipeptidyl peptidase-4 and Kynurenine. His Cardiology research extends to the thematically linked field of Internal medicine. Simon Scharpé combines topics linked to Hemodynamics with his work on Endocrinology.
Simon Scharpé usually deals with Biochemistry and limits it to topics linked to Function and In vivo, Gel electrophoresis, Enzyme, Fibril and Enzyme assay. His Dipeptidyl peptidase-4 research integrates issues from U937 cell, Cancer research, Protease, Fibroblast activation protein, alpha and Dipeptidyl peptidase. His Kynurenine study integrates concerns from other disciplines, such as Anesthesia, Kynurenic acid and Neuroprotection.
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Dipeptidyl-peptidase IV from bench to bedside: an update on structural properties, functions, and clinical aspects of the enzyme DPP IV.
Anne-Marie Lambeir;Christine Durinx;Simon Scharpé;Ingrid De Meester.
Critical Reviews in Clinical Laboratory Sciences (2003)
The effects of psychological stress on humans: increased production of pro-inflammatory cytokines and a Th1-like response in stress-induced anxiety
Michael Maes;Cai Song;Aihua Lin;Raf De Jongh.
CD26, let it cut or cut it down
Ingrid De Meester;Stephan Korom;Stephan Korom;Jo Van Damme;Simon Scharpé.
Immunology Today (1999)
Kynurenine pathway in major depression: evidence of impaired neuroprotection.
Aye Mu Myint;Aye Mu Myint;Yong Ku Kim;Robert Verkerk;Simon Scharpé.
Journal of Affective Disorders (2007)
Proline motifs in peptides and their biological processing.
G Vanhoof;F Goossens;I De Meester;D Hendriks.
The FASEB Journal (1995)
IDO and interferon-alpha-induced depressive symptoms: a shift in hypothesis from tryptophan depletion to neurotoxicity
Marieke C. Wichers;G.H. Koek;Geert Robaeys;R. Verkerk.
Molecular Psychiatry (2005)
Interleukin-1 beta: a putative mediator of HPA axis hyperactivity in major depression?
Michael Maes;Eugène Bosmans;Herbert Y. Meltzer;Simon Scharpé.
American Journal of Psychiatry (1993)
Relationships between interleukin-6 activity, acute phase proteins, and function of the hypothalamic-pituitary-adrenal axis in severe depression.
Michael Maes;Simon Scharpé;Herbert Y. Meltzer;Eugène Bosmans.
Psychiatry Research-neuroimaging (1993)
Acute phase proteins in schizophrenia, mania and major depression: modulation by psychotropic drugs
Michael Maes;Joris Delange;Rakesch Ranjan;Herbert Y. Meltzer.
Psychiatry Research-neuroimaging (1997)
Amino-terminal truncation of chemokines by CD26/dipeptidyl-peptidase IV. Conversion of RANTES into a potent inhibitor of monocyte chemotaxis and HIV-1-infection.
Paul Proost;Ingrid De Meester;Dominique Schols;Sofie Struyf.
Journal of Biological Chemistry (1998)
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