Simon Scharpé

Overview

Best Publications

• Dipeptidyl-peptidase IV from bench to bedside: an update on structural properties, functions, and clinical aspects of the enzyme DPP IV.

  Anne-Marie Lambeir;Christine Durinx;Simon Scharpé;Ingrid De Meester

  1307
  Citations

• The effects of psychological stress on humans: increased production of pro-inflammatory cytokines and a Th1-like response in stress-induced anxiety

  Michael Maes;Cai Song;Aihua Lin;Raf De Jongh

  1004
  Citations

• CD26, let it cut or cut it down

  Ingrid De Meester;Stephan Korom;Stephan Korom;Jo Van Damme;Simon Scharpé

  673
  Citations

• Kynurenine pathway in major depression: evidence of impaired neuroprotection.

  Aye Mu Myint;Aye Mu Myint;Yong Ku Kim;Robert Verkerk;Simon Scharpé

  635
  Citations

• Proline motifs in peptides and their biological processing.

  G Vanhoof;F Goossens;I De Meester;D Hendriks

  625
  Citations

• IDO and interferon-alpha-induced depressive symptoms: a shift in hypothesis from tryptophan depletion to neurotoxicity

  Marieke C. Wichers;G.H. Koek;Geert Robaeys;R. Verkerk

  570
  Citations

• Interleukin-1 beta: a putative mediator of HPA axis hyperactivity in major depression?

  Michael Maes;Eugène Bosmans;Herbert Y. Meltzer;Simon Scharpé

  485
  Citations

• Relationships between interleukin-6 activity, acute phase proteins, and function of the hypothalamic-pituitary-adrenal axis in severe depression.

  Michael Maes;Simon Scharpé;Herbert Y. Meltzer;Eugène Bosmans

  482
  Citations

• Acute phase proteins in schizophrenia, mania and major depression: modulation by psychotropic drugs

  Michael Maes;Joris Delange;Rakesch Ranjan;Herbert Y. Meltzer

  418
  Citations

• Amino-terminal truncation of chemokines by CD26/dipeptidyl-peptidase IV. Conversion of RANTES into a potent inhibitor of monocyte chemotaxis and HIV-1-infection.

  Paul Proost;Ingrid De Meester;Dominique Schols;Sofie Struyf

  412
  Citations

• Increased Serum Interleukin-8 in Patients with Early and Metastatic Breast Cancer Correlates with Early Dissemination and Survival

  Ina H. Benoy;Roberto Salgado;Peter Van Dam;Katrien Geboers

  399
  Citations

• The inflammatory response system in treatment-resistant schizophrenia: increased serum interleukin-6

  A Lin;G Kenis;S Bignotti;G.-J.-B Tura

  397
  Citations

• Molecular characterization of dipeptidyl peptidase activity in serum: soluble CD26/dipeptidyl peptidase IV is responsible for the release of X-Pro dipeptides.

  Christine Durinx;Anne-Marie Lambeir;Eugène Bosmans;Jean-Bernard Falmagne

  394
  Citations

• The monocyte-T-lymphocyte hypothesis of major depression.

  Michael Maes;Ronald Smith;Simon Scharpe

  393
  Citations

• Kinetic Investigation of Chemokine Truncation by CD26/Dipeptidyl Peptidase IV Reveals a Striking Selectivity within the Chemokine Family

  Anne-Marie Lambeir;Paul Proost;Christine Durinx;Gunther Bal

  352
  Citations

• Increased neopterin and interferon-gamma secretion and lower availability of L-tryptophan in major depression: further evidence for an immune response.

  Michael Maes;Simon Scharpé;Herbert Y. Meltzer;Ghadeer Okayli

  352
  Citations

• The inflammatory response system and the availability of plasma tryptophan in patients with primary sleep disorders and major depression

  Cai Song;Aihua Lin;Stefania Bonaccorso;Carine Heide

  332
  Citations

• Hypozincemia in depression

  M. Maes;P.C. D'Haese;S. Scharpé;P. D'Hondt

  293
  Citations

• Increased 24-hour urinary cortisol excretion in patients with post-traumatic stress disorder and patients with major depression, but not in patients with fibromyalgia.

  M Maes;A Lin;S Bonaccorso;F van Hunsel

  285
  Citations

• Research report Kynurenine pathway in major depression: Evidence of impaired neuroprotection

  Aye-Mu Myint;Yong Ku Kim;Robert Verkerk;Simon Scharpé

  0
  Citations