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Ingrid De Meester

Ingrid De Meester

D-Index & Metrics

Biology and Biochemistry

D-Index
66
Citations
15298
World Ranking
8692
National Ranking
151

Overview

Ingrid De Meester is affiliated with the University of Antwerp in Belgium. Their research primarily spans the fields of Medicine and Biochemistry, Genetics and Molecular Biology, with a focus on several subfields including Oncology, Surgery, Cellular and Molecular Neuroscience, Molecular Biology, and Endocrinology, Diabetes and Metabolism.

Their work encompasses a range of topics, notably Peptidase Inhibition and Analysis, Neuropeptides and Animal Physiology, Protease and Inhibitor Mechanisms, Cardiac Structural Anomalies and Repair, Diabetes Treatment and Management, Signaling Pathways in Disease, and Radiopharmaceutical Chemistry and Applications.

Frequent publication venues for De Meester include the Journal of Medicinal Chemistry and Nuclear Medicine and Biology, each with five publications. Other notable venues are the International Journal of Molecular Sciences with four publications, Cancers with three, and the European Journal of Medicinal Chemistry also with three publications.

Notable recent papers authored or co-authored by De Meester are:

  • Targeting fibroblast activation protein (FAP): next generation PET radiotracers using squaramide coupled bifunctional DOTA and DATA5m chelators, 2020, EJNMMI Radiopharmacy and Chemistry
  • Novel Generation of FAP Inhibitor-Based Homodimers for Improved Application in Radiotheranostics, 2023, Cancers
  • A novel serine protease inhibitor as potential treatment for dry eye syndrome and ocular inflammation, 2020, Scientific Reports
  • Native, Intact Glucagon-Like Peptide 1 Is a Natural Suppressor of Thrombus Growth Under Physiological Flow Conditions, 2020, Arteriosclerosis Thrombosis and Vascular Biology
  • In Vitro Evaluation of the Squaramide-Conjugated Fibroblast Activation Protein Inhibitor-Based Agents AAZTA5.SA.FAPi and DOTA.SA.FAPi, 2021, Molecules

De Meester has collaborated frequently with a group of researchers, including Pieter Van der Veken, Koen Augustyns, Yentl Van Rymenant, Emile Verhulst, and Anne-Marie Lambeir.

Best Publications

  • Dipeptidyl-peptidase IV from bench to bedside: an update on structural properties, functions, and clinical aspects of the enzyme DPP IV.

    Anne-Marie Lambeir;Christine Durinx;Simon Scharpé;Ingrid De Meester

  • The effects of psychological stress on humans: increased production of pro-inflammatory cytokines and a Th1-like response in stress-induced anxiety

    Michael Maes;Cai Song;Aihua Lin;Raf De Jongh

  • CD26, let it cut or cut it down

    Ingrid De Meester;Stephan Korom;Stephan Korom;Jo Van Damme;Simon Scharpé

  • Proline motifs in peptides and their biological processing.

    G Vanhoof;F Goossens;I De Meester;D Hendriks

  • Amino-terminal truncation of chemokines by CD26/dipeptidyl-peptidase IV. Conversion of RANTES into a potent inhibitor of monocyte chemotaxis and HIV-1-infection.

    Paul Proost;Ingrid De Meester;Dominique Schols;Sofie Struyf

  • Molecular characterization of dipeptidyl peptidase activity in serum: soluble CD26/dipeptidyl peptidase IV is responsible for the release of X-Pro dipeptides.

    Christine Durinx;Anne-Marie Lambeir;Eugène Bosmans;Jean-Bernard Falmagne

  • Kinetic Investigation of Chemokine Truncation by CD26/Dipeptidyl Peptidase IV Reveals a Striking Selectivity within the Chemokine Family

    Anne-Marie Lambeir;Paul Proost;Christine Durinx;Gunther Bal

  • Processing by CD26/dipeptidyl-peptidase IV reduces the chemotactic and anti-HIV-1 activity of stromal-cell-derived factor-1α

    Paul Proost;Sofie Struyf;Dominique Schols;Christine Durinx

  • Extended Structure–Activity Relationship and Pharmacokinetic Investigation of (4-Quinolinoyl)glycyl-2-cyanopyrrolidine Inhibitors of Fibroblast Activation Protein (FAP)

    Koen Jansen;Leen Heirbaut;Robert Verkerk;Jonathan D Cheng

  • Dipeptidyl-peptidase IV converts intact B-type natriuretic peptide into its des-SerPro form.

    Inger Brandt;Anne-Marie Lambeir;Jean-Marie Ketelslegers;Marc Vanderheyden

  • Selective Inhibitors of Fibroblast Activation Protein (FAP) with a (4-Quinolinoyl)-glycyl-2-cyanopyrrolidine Scaffold.

    Koen Jansen;Leen Heirbaut;Jonathan D. Cheng;Jurgen Joossens

  • Inhibition of CD26/dipeptidyl peptidase IV activity in vivo prolongs cardiac allograft survival in rat recipients

    S. Korom;I. De Meester;T. H. W. Stadlbauer;A. Chandraker

  • Functional comparison of two human monocyte chemotactic protein-2 isoforms, role of the amino-terminal pyroglutamic acid and processing by CD26/dipeptidyl peptidase IV.

    van E Coillie;P. Proost;van I Aelst;S. Struyf

  • Cleavage by CD26/dipeptidyl peptidase IV converts the chemokine LD78beta into a most efficient monocyte attractant and CCR1 agonist.

    Paul Proost;Patricia Menten;Sofie Struyf;Evemie Schutyser

  • The Dipeptidyl Peptidase Family, Prolyl Oligopeptidase, and Prolyl Carboxypeptidase in the Immune System and Inflammatory Disease, Including Atherosclerosis.

    Yannick Waumans;Lesley Baerts;Kaat Kehoe;Anne-Marie Lambeir

  • Natural truncation of RANTES abolishes signaling through the CC chemokine receptors CCR1 and CCR3, impairs its chemotactic potency and generates a CC chemokine inhibitor.

    Sofie Struyf;Ingrid De Meester;Simon Scharpé;Jean-Pierre Lenaerts

  • Relationships between lower plasma L-tryptophan levels and immune-inflammatory variables in depression

    Michael Maes;Herbert Y. Meltzer;Simon Scharpe;Eugène Bosmans

  • Truncation of Macrophage-derived Chemokine by CD26/ Dipeptidyl-Peptidase IV beyond Its Predicted Cleavage Site Affects Chemotactic Activity and CC Chemokine Receptor 4 Interaction

    Paul Proost;Sofie Struyf;Dominique Schols;Ghislain Opdenakker

  • Inhibition of dipeptidyl-peptidase IV catalyzed peptide truncation by Vildagliptin ((2S)-{[(3-hydroxyadamantan-1-yl)amino]acetyl}-pyrrolidine-2-carbonitrile).

    Inger Brandt;Jurgen Joossens;Xin Chen;Marie-Berthe Maes

  • Serine peptidase modulators

    Simon Scharpe;Ingrid De Meester;Anne-Marie Lambeir;Koen Augustyns

Frequent Co-Authors

Simon Scharpé
Simon Scharpé University of Antwerp
Anne-Marie Lambeir
Anne-Marie Lambeir University of Antwerp
Koen Augustyns
Koen Augustyns University of Antwerp
Paul Proost
Paul Proost KU Leuven
Jo Van Damme
Jo Van Damme Rega Institute for Medical Research
Walter Weder
Walter Weder University of Zurich
Sofie Struyf
Sofie Struyf KU Leuven
Jan Balzarini
Jan Balzarini KU Leuven
Erik Fransen
Erik Fransen University of Antwerp

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