His scientific interests lie mostly in Biochemistry, Dipeptidyl peptidase, Fibroblast activation protein, alpha, Molecular biology and Dipeptidyl peptidase-4. His work in the fields of Oligopeptidase, Receptor and Binding site overlaps with other areas such as Aminopeptidase. His Dipeptidyl peptidase research is multidisciplinary, incorporating perspectives in Dipeptidyl Peptidase 9, Point mutation and Gene family.
Mark D. Gorrell combines subjects such as Hepatic stellate cell, Protease, Enzyme, Immunology and Extracellular matrix with his study of Fibroblast activation protein, alpha. His study looks at the relationship between Dipeptidyl peptidase-4 and fields such as Serine protease, as well as how they intersect with chemical problems. His biological study spans a wide range of topics, including Internal medicine, Gene expression, Gene expression profiling and Endocrinology.
His primary scientific interests are in Biochemistry, Dipeptidyl peptidase, Fibroblast activation protein, alpha, Dipeptidyl peptidase-4 and Molecular biology. His Biochemistry study incorporates themes from Dipeptidyl peptidase 8 and Monoclonal antibody. His Dipeptidyl peptidase research is multidisciplinary, incorporating elements of Oligopeptidase, Dipeptidyl Peptidase 9, Adenosine deaminase and Gene family.
The Fibroblast activation protein, alpha study combines topics in areas such as Cancer research, Inflammation, Immunology, Downregulation and upregulation and Cell biology. His research investigates the connection with Immunology and areas like Internal medicine which intersect with concerns in Type 2 diabetes. His work deals with themes such as Primary biliary cirrhosis, Complementary DNA, Real-time polymerase chain reaction, Gene and Chemokine, which intersect with Molecular biology.
His primary areas of investigation include Fibroblast activation protein, alpha, Cancer research, Dipeptidyl peptidase-4, Biochemistry and Inflammation. The concepts of his Fibroblast activation protein, alpha study are interwoven with issues in Downregulation and upregulation, Cell biology, Fibroblast, Sirius Red and Apolipoprotein E. His work carried out in the field of Cancer research brings together such families of science as Liver fibrosis, Biomarker, Ovarian cancer and Gene.
The various areas that he examines in his Dipeptidyl peptidase-4 study include Molecular biology and Dipeptidyl peptidase. He has researched Molecular biology in several fields, including Liver injury, B cell, Immunoglobulin D, Chemokine and Fibrosis. The study incorporates disciplines such as Serine protease, Dipeptidyl Peptidase 9, Cell adhesion and Intracellular in addition to Dipeptidyl peptidase.
His main research concerns Dipeptidyl peptidase-4, Fibrosis, Fibroblast activation protein, alpha, Molecular biology and Disease. His research in Dipeptidyl peptidase-4 intersects with topics in Inflammation, Immunology, Biochemistry and Dipeptidyl peptidase. Mark D. Gorrell has included themes like Fibronectin and Liver injury in his Immunology study.
His Dipeptidyl peptidase study integrates concerns from other disciplines, such as Arthritis, Cancer research, Peptide YY and Focal adhesion. His Fibroblast activation protein, alpha research includes themes of Fibroblast, Protease and Downregulation and upregulation. His research integrates issues of Diabetes mellitus, Type 2 Diabetes Mellitus and Intensive care medicine in his study of Disease.
This overview was generated by a machine learning system which analysed the scientist’s body of work. If you have any feedback, you can contact us here.
Regulation of the Receptor Specificity and Function of the Chemokine RANTES (Regulated on Activation, Normal T Cell Expressed and Secreted) by Dipeptidyl Peptidase IV (CD26)-mediated Cleavage
Tamas Oravecz;Marina Pall;Gregory Roderiquez;Mark D. Gorrell.
Journal of Experimental Medicine (1997)
3-dimensional imaging of collagen using second harmonic generation.
Guy Cox;Eleanor Kable;Allan Jones;Ian Fraser.
Journal of Structural Biology (2003)
CD26: a multifunctional integral membrane and secreted protein of activated lymphocytes.
M. D. Gorrell;V. Gysbers;G. W. McCaughan.
Scandinavian Journal of Immunology (2001)
Dipeptidyl peptidase IV and related enzymes in cell biology and liver disorders.
Mark D. Gorrell.
Clinical Science (2005)
Fibroblast activation protein: a cell surface dipeptidyl peptidase and gelatinase expressed by stellate cells at the tissue remodelling interface in human cirrhosis
Miriam T. Levy;Geoffrey W. McCaughan;Catherine A. Abbott;John E. Park.
Cloning, expression and chromosomal localization of a novel human dipeptidyl peptidase (DPP) IV homolog, DPP8.
Catherine A. Abbott;Denise M. T. Yu;Erica Woollatt;Grant R. Sutherland.
FEBS Journal (2000)
Diabetes and nonalcoholic Fatty liver disease: a pathogenic duo.
K. H. Williams;K. H. Williams;N. A. Shackel;N. A. Shackel;M. D. Gorrell;M. D. Gorrell;S. V. McLennan;S. V. McLennan.
Endocrine Reviews (2013)
Understanding fibroblast activation protein (FAP): Substrates, activities, expression and targeting for cancer therapy
Elizabeth J. Hamson;Fiona M. Keane;Stefan Tholen;Oliver Schilling.
Proteomics Clinical Applications (2014)
Insights into the Pathobiology of Hepatitis C Virus-Associated Cirrhosis : Analysis of Intrahepatic Differential Gene Expression
Nicholas A. Shackel;Peter H. McGuinness;Catherine A. Abbott;Mark D. Gorrell;Mark D. Gorrell.
American Journal of Pathology (2002)
Inhibitor selectivity in the clinical application of dipeptidyl peptidase-4 inhibition
Mark Kirby;Denise M. T. Yu;Stephen P. O'connor;Mark D. Gorrell.
Clinical Science (2010)
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