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132
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Overview

Mark Raffeld is a researcher affiliated with the National Institutes of Health in the United States. Their body of work spans primarily the fields of Medicine and Biochemistry, Genetics, and Molecular Biology, with a significant number of publications related to genetics, oncology, molecular biology, pathology and forensic medicine, and immunology.

The scientist's recent publications illustrate engagement with various topics in cancer biology and diagnostics. These include investigations into biomarkers, tumor heterogeneity, and immune recognition of neoantigens. Notable recent studies include:

  • MGMT Status as a Clinical Biomarker in Glioblastoma, 2020, published in Trends in Cancer
  • Clonal Evolution and Heterogeneity of Osimertinib Acquired Resistance Mechanisms in EGFR Mutant Lung Cancer, 2020, published in Cell Reports Medicine
  • Antigen Experienced T Cells from Peripheral Blood Recognize p53 Neoantigens, 2020, published in Clinical Cancer Research
  • Randomized Phase II Study of First-Line Cladribine With Concurrent or Delayed Rituximab in Patients With Hairy Cell Leukemia, 2020, published in Journal of Clinical Oncology
  • Impact of the methylation classifier and ancillary methods on CNS tumor diagnostics, 2021, published in Neuro-Oncology

Frequently collaborating with other researchers, Mark Raffeld has coauthored extensively with individuals including Liqiang Xi, Stefania Pittaluga, Kenneth Aldape, Svetlana Pack, and Hao-Wei Wang. These collaborations indicate an interdisciplinary and multi-institutional approach to scientific research.

Their work has been distributed across various publication venues, with the most frequent being:

  • The American Journal of Surgical Pathology (7 publications)
  • Journal of Clinical Oncology (6 publications)
  • Blood (6 publications)
  • Acta Neuropathologica (5 publications)
  • Clinical Cancer Research (3 publications)

Mark Raffeld's research covers a range of topics, with a focus on both diagnostic and treatment-related aspects of oncology and hematology. Some main topics of their work include:

  • Lymphoma Diagnosis and Treatment
  • Glioma Diagnosis and Treatment
  • Chronic Lymphocytic Leukemia Research
  • Viral-associated Cancers and Disorders
  • Cancer Genomics and Diagnostics
  • Cutaneous Lymphoproliferative Disorders Research
  • Neuroblastoma Research and Treatments

The diverse subfields and topics linked with their research demonstrate a broad expertise oriented toward cancer biology, diagnostics, and immunological aspects of tumor development and treatment.

Best Publications

  • Cancer Regression and Autoimmunity in Patients After Clonal Repopulation with Antitumor Lymphocytes

    Mark E. Dudley;John R. Wunderlich;Paul F. Robbins;James C. Yang

  • Gene-Expression Profiles in Hereditary Breast Cancer

    I Hedenfalk;D Duggan;Y Chen;M Radmacher

  • Chemotherapy-Refractory Diffuse Large B-Cell Lymphoma and Indolent B-Cell Malignancies Can Be Effectively Treated With Autologous T Cells Expressing an Anti-CD19 Chimeric Antigen Receptor

    James N. Kochenderfer;Mark E. Dudley;Sadik H. Kassim;Robert P.T. Somerville

  • Tumor Regression in Patients With Metastatic Synovial Cell Sarcoma and Melanoma Using Genetically Engineered Lymphocytes Reactive With NY-ESO-1

    Paul F. Robbins;Richard A. Morgan;Steven A. Feldman;James C. Yang

  • Eradication of B-lineage cells and regression of lymphoma in a patient treated with autologous T cells genetically engineered to recognize CD19

    James N. Kochenderfer;Wyndham H. Wilson;John E. Janik;Mark E. Dudley

  • Activated STING in a Vascular and Pulmonary Syndrome

    Y. Liu;A.A. Jesus;B. Marrero;D. Yang

  • ZAP-70 expression identifies a chronic lymphocytic leukemia subtype with unmutated immunoglobulin genes, inferior clinical outcome, and distinct gene expression profile

    Adrian Wiestner;Andreas Rosenwald;Todd S. Barry;George Wright

  • The lymph node microenvironment promotes B-cell receptor signaling, NF-κB activation, and tumor proliferation in chronic lymphocytic leukemia

    Yair Herishanu;Patricia Pérez-Galán;Delong Liu;Angélique Biancotto

  • Human mesenchymal stem cells exert potent antitumorigenic effects in a model of Kaposi's sarcoma

    Aarif Y. Khakoo;Aarif Y. Khakoo;Shibani Pati;Stasia A. Anderson;William Reid

  • A Pilot Trial Using Lymphocytes Genetically Engineered with an NY-ESO-1-Reactive T-cell Receptor: Long-term Follow-up and Correlates with Response

    Paul F. Robbins;Sadik H. Kassim;Thai Lan N. Tran;Jessica S. Crystal

  • Mantle-cell lymphoma.

    E Campo;M Raffeld;E S Jaffe

  • B-cell Maturation Antigen Is a Promising Target for Adoptive T-cell Therapy of Multiple Myeloma

    Robert O. Carpenter;Moses O. Evbuomwan;Stefania Pittaluga;Jeremy J. Rose

  • Mutations in GATA2 are associated with the autosomal dominant and sporadic monocytopenia and mycobacterial infection (MonoMAC) syndrome

    Amy P. Hsu;Elizabeth P. Sampaio;Javed Khan;Katherine R. Calvo

  • Synergy between basic fibroblast growth factor and HIV-1 Tat protein in induction of Kaposi's sarcoma

    Barbara Ensoli;Rita Gendelman;Phillip Markham;Valeria Fiorelli

  • Helper virus induced T cell lymphoma in nonhuman primates after retroviral mediated gene transfer.

    R E Donahue;S W Kessler;D Bodine;K McDonagh

  • EBV positive mucocutaneous ulcer--a study of 26 cases associated with various sources of immunosuppression

    Stefan D Dojcinov;Girish Venkataraman;Mark Raffeld;Stefania Pittaluga

  • p53 mutation is associated with progression in follicular lymphomas

    Christian A. Sander;Takahiro Yano;Helen M. Clark;Cynthia Harris

  • Pulmonary Nontuberculous Mycobacterial Disease: Prospective Study of a Distinct Preexisting Syndrome

    Richard D. Kim;David E. Greenberg;Mary E. Ehrmantraut;Shireen V. Guide

  • Immuno-LCM: laser capture microdissection of immunostained frozen sections for mRNA analysis.

    Falko Fend;Michael R. Emmert-Buck;Rodrigo Chuaqui;Kristina Cole

  • Highly effective treatment of acquired immunodeficiency syndrome-related lymphoma with dose-adjusted EPOCH: impact of antiretroviral therapy suspension and tumor biology

    Richard F. Little;Stefania Pittaluga;Nicole Grant;Seth M. Steinberg

Frequent Co-Authors

Elaine S. Jaffe
Elaine S. Jaffe National Institutes of Health
Stefania Pittaluga
Stefania Pittaluga National Institutes of Health
Maryalice Stetler-Stevenson
Maryalice Stetler-Stevenson National Institutes of Health
Seth M. Steinberg
Seth M. Steinberg National Institutes of Health
Wyndham H. Wilson
Wyndham H. Wilson National Institutes of Health
Svetlana Pack
Svetlana Pack National Institutes of Health
Robert J. Kreitman
Robert J. Kreitman National Cancer Institute
Leticia Quintanilla-Martinez
Leticia Quintanilla-Martinez University of Tübingen
Julie Teruya-Feldstein
Julie Teruya-Feldstein Icahn School of Medicine at Mount Sinai
Steven A. Rosenberg
Steven A. Rosenberg National Institutes of Health

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