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Biology and Biochemistry

D-Index
76
Citations
16274
World Ranking
5152
National Ranking
2454

Overview

Raphael A. Nemenoff is affiliated with the University of Colorado Anschutz Medical Campus in the United States. Their research spans several fields including biochemistry, genetics and molecular biology, immunology and microbiology, and medicine. The scientist focuses on molecular biology, immunology, genetics, cancer research, and pulmonary and respiratory medicine as notable subfields of study.

The main topics covered in their work include:

  • Kruppel-like factors research
  • Congenital heart defects research
  • Complement system in diseases
  • Genetic and kidney cyst diseases
  • Phagocytosis and immune regulation
  • Immune cell function and interaction
  • Immunotherapy and immune responses

Recent publications by Raphael A. Nemenoff demonstrate a focus on mechanisms of disease and immune regulation. Some selected papers are:

  • "Complement factor H-deficient mice develop spontaneous hepatic tumors," 2020, Journal of Clinical Investigation
  • "Smooth muscle-derived progenitor cell myofibroblast differentiation through KLF4 downregulation promotes arterial remodeling and fibrosis," 2020, JCI Insight
  • "Complement C3a and C5a receptor blockade modulates regulatory T cell conversion in head and neck cancer," 2021, Journal for ImmunoTherapy of Cancer
  • "High Throughput Screen Identifies the DNMT1 (DNA Methyltransferase-1) Inhibitor, 5-Azacytidine, as a Potent Inducer of PTEN (Phosphatase and Tensin Homolog)," 2020, Arteriosclerosis Thrombosis and Vascular Biology
  • "Complement and Cancer-A Dysfunctional Relationship?," 2020, Antibodies

The scientist frequently publishes in journals such as JCI Insight, bioRxiv (Cold Spring Harbor Laboratory), Arteriosclerosis Thrombosis and Vascular Biology, Journal of the American Society of Nephrology, and Journal of Clinical Investigation.

Collaborations are notable with coauthors including Sizhao Lu, Austin Jolly, Allison Dubner, Karen S. Moulton, and Keith A. Strand, each contributing to multiple publications alongside this researcher.

Best Publications

  • Phosphorylation and activation of a high molecular weight form of phospholipase A2 by p42 microtubule-associated protein 2 kinase and protein kinase C.

    Raphael A. Nemenoff;Sim Winitz;Nan Xin Qian;Vicki Van Putten

  • Transmigrating Neutrophils Shape the Mucosal Microenvironment through Localized Oxygen Depletion to Influence Resolution of Inflammation

    Eric L. Campbell;Walter J. Bruyninckx;Caleb J. Kelly;Louise E. Glover

  • Analysis of Orthologous Gene Expression between Human Pulmonary Adenocarcinoma and a Carcinogen-Induced Murine Model

    Robert S. Stearman;Lori Dwyer-Nield;Laura Zerbe;Stacy A. Blaine

  • Peroxisome Proliferator-Activated Receptor Gamma (PPARγ) Expression Is Decreased in Pulmonary Hypertension and Affects Endothelial Cell Growth

    Shingo Ameshima;Heiko Golpon;Carlyne D. Cool;Daniel Chan

  • Insulin-stimulated tyrosine phosphorylation of the insulin receptor in detergent extracts of human placental membranes. Comparison to epidermal growth factor-stimulated phosphorylation.

    J Avruch;R A Nemenoff;P J Blackshear;M W Pierce

  • Fibroblast Growth Factor (FGF) and FGF Receptor-Mediated Autocrine Signaling in Non-Small-Cell Lung Cancer Cells

    Lindsay Marek;Kathryn E. Ware;Alexa Fritzsche;Paula Hercule

  • Identification and characterization of a hormonally regulated form of phospholipase A2 in rat renal mesangial cells.

    J H Gronich;J V Bonventre;R A Nemenoff

  • Identification of Insulin Receptor Tyrosine Residues Autophosphorylated in Vitro

    H E Tornqvist;M W Pierce;A R Frackelton;R A Nemenoff

  • Hypoxic Activation of Adventitial Fibroblasts*: Role in Vascular Remodeling

    Kurt R. Stenmark;Evgenia Gerasimovskaya;Raphael A. Nemenoff;Mita Das

  • Resistance to Radiotherapy and PD-L1 Blockade Is Mediated by TIM-3 Upregulation and Regulatory T-Cell Infiltration

    Ayman Oweida;Mohammad Hararah;Andy V Phan;David C. Binder

  • Induction of Cytosolic Phospholipase A2 by Oncogenic Ras in Human Non-small Cell Lung Cancer

    Lynn E. Heasley;Seth Thaler;Michael Nicks;Brenda Price

  • Purification of a high-molecular-mass form of phospholipase A2 from rat kidney activated at physiological calcium concentrations.

    J H Gronich;J V Bonventre;R A Nemenoff

  • Cox-2 inactivates Smad signaling and enhances EMT stimulated by TGF-β through a PGE2-dependent mechanisms

    Jason R. Neil;Kyle M. Johnson;Raphael A. Nemenoff;William P. Schiemann

  • Insulin stimulation of (Na+,K+)-adenosine triphosphatase-dependent 86Rb+ uptake in rat adipocytes.

    M D Resh;R A Nemenoff;G Guidotti

  • Restoration of Wnt-7a Expression Reverses Non-small Cell Lung Cancer Cellular Transformation through Frizzled-9-mediated Growth Inhibition and Promotion of Cell Differentiation

    Robert A. Winn;Robert A. Winn;Lindsay Marek;Sun-Young Han;Karen Rodriguez

  • Identification of the insulin receptor tyrosine residues undergoing insulin-stimulated phosphorylation in intact rat hepatoma cells.

    H E Tornqvist;J R Gunsalus;R A Nemenoff;A R Frackelton

  • Manipulation of pulmonary prostacyclin synthase expression prevents murine lung cancer

    Robert L. Keith;York E. Miller;Yasushi Hoshikawa;Mark D. Moore

  • Peroxisome Proliferator-Activated Receptor-γ Is a Target of Nonsteroidal Anti-Inflammatory Drugs Mediating Cyclooxygenase-Independent Inhibition of Lung Cancer Cell Growth

    Marilee Wick;Greg Hurteau;Christina Dessev;Daniel Chan

  • Differentiated Smooth Muscle Cells Generate a Subpopulation of Resident Vascular Progenitor Cells in the Adventitia Regulated by Klf4

    Mark W. Majesky;Henrick Horita;Allison Ostriker;Sizhao Lu

  • Selective Class I Histone Deacetylase Inhibition Suppresses Hypoxia-Induced Cardiopulmonary Remodeling Through an Antiproliferative Mechanism

    Maria A. Cavasin;Kim Demos-Davies;Todd R. Horn;Lori A. Walker

Frequent Co-Authors

Lynn E. Heasley
Lynn E. Heasley University of Colorado Anschutz Medical Campus
Robert W. Schrier
Robert W. Schrier University of Colorado Denver
Charles L. Edelstein
Charles L. Edelstein University of Colorado Denver
Kurt R. Stenmark
Kurt R. Stenmark University of Colorado Anschutz Medical Campus
Joseph V. Bonventre
Joseph V. Bonventre Brigham and Women's Hospital
Harold A. Scheraga
Harold A. Scheraga Cornell University
Wilbur A. Franklin
Wilbur A. Franklin University of Colorado Denver
Paul A. Bunn
Paul A. Bunn University of Colorado Boulder
Alvin M. Malkinson
Alvin M. Malkinson University of Colorado Denver
Joseph Avruch
Joseph Avruch Harvard University

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