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Medicine

D-Index
83
Citations
51565
World Ranking
15340
National Ranking
7736

Overview

Charles L. Edelstein is affiliated with the University of Colorado Denver in the United States and has contributed extensively to research in medicine and biochemistry, genetics, and molecular biology. Their work focuses primarily on nephrology and related genetic fields.

The scientist's recent research encompasses topics such as genetic and kidney cyst diseases, biomedical research and pathophysiology, autophagy in disease and therapy, renal and related cancers, genetic syndromes and imprinting, acute kidney injury research, and chemotherapy-induced organ toxicity mitigation.

Frequent coauthors collaborating with Edelstein include:

  • Daniel Atwood
  • Özgür Akın Oto
  • Katharina Hopp
  • Deepak Pokhrel
  • Anjana Chaudhary

They have published in several well-known venues, with significant contributions in:

  • Journal of the American Society of Nephrology (18 publications)
  • Cellular Signalling (4 publications)
  • Kidney International Reports (3 publications)
  • Kidney International (1 publication)
  • Kidney360 (1 publication)

Among their recent papers are:

  • "Overview of Antibiotic-Induced Nephrotoxicity" (2023, Kidney International Reports)
  • "Autophagy inhibition by chloroquine and hydroxychloroquine could adversely affect acute kidney injury and other organ injury in critically ill patients with COVID-19" (2020, Kidney International)
  • "Increased mTOR and suppressed autophagic flux in the heart of a hypomorphic Pkd1 mouse model of autosomal dominant polycystic kidney disease" (2020, Cellular Signalling)
  • "The effect of MEK1/2 inhibitors on cisplatin-induced acute kidney injury (AKI) and cancer growth in mice" (2020, Cellular Signalling)
  • "The effect of trehalose on autophagy-related proteins and cyst growth in a hypomorphic Pkd1 mouse model of autosomal dominant polycystic kidney disease" (2020, Cellular Signalling)

Edelstein has contributed scholarly work mainly in the fields of:

  • Medicine
  • Biochemistry, Genetics and Molecular Biology

The subfields of study they focus on include:

  • Genetics
  • Molecular Biology
  • Nephrology
  • Pathology and Forensic Medicine
  • Epidemiology

Best Publications

  • Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition)

    Daniel J. Klionsky;Amal Kamal Abdel-Aziz;Sara Abdelfatah;Mahmoud Abdellatif

  • Guidelines for the use and interpretation of assays for monitoring autophagy

    Daniel J. Klionsky;Fabio C. Abdalla;Hagai Abeliovich;Robert T. Abraham

  • Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)

    Daniel J. Klionsky;Kotb Abdelmohsen;Akihisa Abe;Joynal Abedin

  • Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)

    Daniel J. Klionsky;Kotb Abdelmohsen;Akihisa Abe;Joynal Abedin

  • Urinary IL-18 is an early predictive biomarker of acute kidney injury after cardiac surgery.

    C.R. Parikh;J. Mishra;H. Thiessen-Philbrook;B. Dursun

  • Urine IL-18 Is an Early Diagnostic Marker for Acute Kidney Injury and Predicts Mortality in the Intensive Care Unit

    Chirag R. Parikh;Edward Abraham;Marek Ancukiewicz;Charles L. Edelstein

  • Urinary interleukin-18 is a marker of human acute tubular necrosis.

    Chirag R. Parikh;Alkesh Jani;Vyacheslav Y. Melnikov;Sarah Faubel

  • Pathophysiology of cisplatin-induced acute kidney injury.

    Abdullah Ozkok;Charles L. Edelstein

  • Urine NGAL and IL-18 are predictive biomarkers for delayed graft function following kidney transplantation.

    C. R. Parikh;A. Jani;J. Mishra;Q. Ma

  • Mediators of Inflammation in Acute Kidney Injury

    Ali Akcay;Quocan Nguyen;Charles L. Edelstein

  • Impaired IL-18 processing protects caspase-1–deficient mice from ischemic acute renal failure

    Vyacheslav Y. Melnikov;Tevfik Ecder;Giamila Fantuzzi;Britta Siegmund

  • Postoperative Biomarkers Predict Acute Kidney Injury and Poor Outcomes after Pediatric Cardiac Surgery

    Chirag R. Parikh;Prasad Devarajan;Michael Zappitelli;Kyaw Sint;Kyaw Sint

  • Rapamycin Markedly Slows Disease Progression in a Rat Model of Polycystic Kidney Disease

    Yunxia Tao;Jun Kim;Robert W. Schrier;Charles L. Edelstein

  • Neutrophil-independent mechanisms of caspase-1– and IL-18–mediated ischemic acute tubular necrosis in mice

    Vyacheslav Y. Melnikov;Sarah Faubel;Britta Siegmund;M. Scott Lucia

  • Cisplatin-Induced Acute Renal Failure Is Associated with an Increase in the Cytokines Interleukin (IL)-1β, IL-18, IL-6, and Neutrophil Infiltration in the Kidney

    Sarah Faubel;Eli C. Lewis;Leonid Reznikov;Danica Ljubanovic

  • Fractionation of human serum high density lipoprotein in urea solutions. Evidence for polypeptide heterogeneity.

    Angelo Scanu;J. Toth;C. Edelstein;S. Koga

  • Lack of a Functional Alternative Complement Pathway Ameliorates Ischemic Acute Renal Failure in Mice

    Joshua M. Thurman;Danica Ljubanovic;Charles L. Edelstein;Gary S. Gilkeson

  • Cardiac and Renal Effects of Standard Versus Rigorous Blood Pressure Control in Autosomal-Dominant Polycystic Kidney Disease: Results of a Seven-Year Prospective Randomized Study

    Robert Schrier;Kimberly McFann;Ann Johnson;Arlene Chapman

  • Improved performance of urinary biomarkers of acute kidney injury in the critically ill by stratification for injury duration and baseline renal function.

    Zoltán H. Endre;Zoltán H. Endre;John W. Pickering;Robert J. Walker;Prasad Devarajan

  • The nature of renal cell injury

    Charles L. Edelstein;Hong Ling;Robert W. Schrier

Frequent Co-Authors

Robert W. Schrier
Robert W. Schrier University of Colorado Denver
Chirag R. Parikh
Chirag R. Parikh Johns Hopkins University
Prasad Devarajan
Prasad Devarajan Cincinnati Children's Hospital Medical Center
Raphael A. Nemenoff
Raphael A. Nemenoff University of Colorado Anschutz Medical Campus
Amit X. Garg
Amit X. Garg University of Western Ontario
Sergio Lavandero
Sergio Lavandero University of Chile
Boris Zhivotovsky
Boris Zhivotovsky Karolinska Institute
Evelina Gatti
Evelina Gatti Aix-Marseille University
Andrew Thorburn
Andrew Thorburn University of Colorado Denver
Steven G. Coca
Steven G. Coca Icahn School of Medicine at Mount Sinai

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