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Biology and Biochemistry

D-Index
110
Citations
44170
World Ranking
969
National Ranking
598

Medicine

D-Index
110
Citations
44172
World Ranking
5568
National Ranking
2998

Overview

Sean P. Colgan is affiliated with the University of Colorado Anschutz Medical Campus in the United States. Their research predominantly spans the fields of Biochemistry, Genetics and Molecular Biology, and Medicine. Within these domains, they have contributed extensively to subfields such as Molecular Biology, Immunology, Physiology, Cancer Research, and Genetics.

The scientist's work covers key topics including:

  • Gut microbiota and health
  • Cancer, Hypoxia, and Metabolism
  • Diet and metabolism studies
  • Inflammatory Bowel Disease
  • Cancer Research and Treatments
  • Barrier Structure and Function Studies
  • Immune cells in cancer

Sean P. Colgan has authored several influential papers, among which are:

  • "Microbiota-derived butyrate dynamically regulates intestinal homeostasis through regulation of actin-associated protein synaptopodin," 2020, Proceedings of the National Academy of Sciences
  • "Hypoxia and Innate Immunity: Keeping Up with the HIFsters," 2020, Annual Review of Immunology
  • "Creatine Transporter, Reduced in Colon Tissues From Patients With Inflammatory Bowel Diseases, Regulates Energy Balance in Intestinal Epithelial Cells, Epithelial Integrity, and Barrier Function," 2020, Gastroenterology
  • "Monocyte-derived macrophages orchestrate multiple cell-type interactions to repair necrotic liver lesions in disease models," 2023, Journal of Clinical Investigation
  • "Microbiota-Sourced Purines Support Wound Healing and Mucous Barrier Function," 2020, iScience

The scientist frequently publishes in several notable venues including:

  • The FASEB Journal (13 publications)
  • Gastroenterology (9 publications)
  • bioRxiv (Cold Spring Harbor Laboratory) (7 publications)
  • Inflammatory Bowel Diseases (6 publications)
  • Gut Microbes (5 publications)

Sean P. Colgan collaborates regularly with a number of co-authors, with whom they have multiple joint publications. Frequent collaborators include:

  • Ian M. Cartwright (34 collaborative works)
  • Alexander S. Dowdell (28 collaborative works)
  • Nichole Welch (18 collaborative works)
  • J. Scott Lee (16 collaborative works)
  • Rachael Kostelecky (16 collaborative works)

Best Publications

  • Resolvins: a family of bioactive products of omega-3 fatty acid transformation circuits initiated by aspirin treatment that counter proinflammation signals.

    Charles N. Serhan;Song Hong;Karsten Gronert;Sean P. Colgan

  • Novel Functional Sets of Lipid-Derived Mediators with Antiinflammatory Actions Generated from Omega-3 Fatty Acids via Cyclooxygenase 2–Nonsteroidal Antiinflammatory Drugs and Transcellular Processing

    Charles N. Serhan;Clary B. Clish;Jessica Brannon;Sean P. Colgan

  • Crosstalk between Microbiota-Derived Short-Chain Fatty Acids and Intestinal Epithelial HIF Augments Tissue Barrier Function

    Caleb J Kelly;Leon Zheng;Eric L Campbell;Bejan J Saeedi

  • Hypoxia-inducible Factor-1-dependent Regulation of the Multidrug Resistance (MDR1) Gene

    Katrina M. Comerford;Timothy J. Wallace;Jörn Karhausen;Nancy A. Louis

  • Ecto-5′-nucleotidase (CD73) regulation by hypoxia-inducible factor-1 mediates permeability changes in intestinal epithelia

    Kristin Synnestvedt;Glenn T. Furuta;Katrina M. Comerford;Nancy Louis

  • Epithelial hypoxia-inducible factor-1 is protective in murine experimental colitis

    Jörn Karhausen;Glenn T. Furuta;John E. Tomaszewski;Randall S. Johnson

  • Crucial Role for Ecto-5′-Nucleotidase (CD73) in Vascular Leakage during Hypoxia

    Linda F. Thompson;Holger K. Eltzschig;Juan C. Ibla;Juan C. Ibla;C. Justin Van De Wiele

  • Resolvin D1 and Its Aspirin-triggered 17R Epimer STEREOCHEMICAL ASSIGNMENTS, ANTI-INFLAMMATORY PROPERTIES, AND ENZYMATIC INACTIVATION

    Yee Ping Sun;Sungwhan F. Oh;Jasim Uddin;Rong Yang

  • Hypoxia-inducible factor-1 alpha–dependent induction of FoxP3 drives regulatory T-cell abundance and function during inflammatory hypoxia of the mucosa

    Eric T. Clambey;Eóin N. McNamee;Joseph A. Westrich;Louise E. Glover

  • Regulation of immunity and inflammation by hypoxia in immunological niches

    Cormac T. Taylor;Sean P. Colgan

  • Anti-Inflammatory Actions of Neuroprotectin D1/Protectin D1 and Its Natural Stereoisomers: Assignments of Dihydroxy-Containing Docosatrienes

    Charles N. Serhan;Katherine Gotlinger;Song Hong;Yan Lu

  • Coordinated Adenine Nucleotide Phosphohydrolysis and Nucleoside Signaling in Posthypoxic Endothelium Role of Ectonucleotidases and Adenosine A2B Receptors

    Holger K. Eltzschig;Juan C. Ibla;Glenn T. Furuta;Martin O. Leonard

  • Physiological roles for ecto-5'-nucleotidase (CD73).

    Sean P. Colgan;Holger K. Eltzschig;Holger K. Eltzschig;Tobias Eckle;Linda F. Thompson;Linda F. Thompson;Linda F. Thompson

  • Salmonella typhimurium attachment to human intestinal epithelial monolayers: transcellular signalling to subepithelial neutrophils.

    Beth A. McCormick;Sean P. Colgan;Charlene Delp-Archer;Samuel I. Miller

  • Hypoxia-Inducible Factor 1–Dependent Induction of Intestinal Trefoil Factor Protects Barrier Function during Hypoxia

    Glenn T. Furuta;Jerrold R. Turner;Cormac T. Taylor;Robert M. Hershberg

  • Rho protein regulates tight junctions and perijunctional actin organization in polarized epithelia.

    A Nusrat;M Giry;J R Turner;S P Colgan

  • Metabolic Shifts in Immunity and Inflammation

    Douglas J. Kominsky;Eric L. Campbell;Sean P. Colgan

  • Hypoxia: an alarm signal during intestinal inflammation.

    Sean P. Colgan;Cormac T. Taylor

  • Physiologic hypoxia and oxygen homeostasis in the healthy intestine. A Review in the Theme: Cellular Responses to Hypoxia

    Leon Zheng;Caleb J Kelly;Sean Patrick Colgan

  • NLRP3 inflammasome plays a key role in the regulation of intestinal homeostasis

    Simon A. Hirota;Jeffrey Ng;Alan Lueng;Maitham Khajah

Frequent Co-Authors

Holger K. Eltzschig
Holger K. Eltzschig The University of Texas Health Science Center at Houston
Glenn T. Furuta
Glenn T. Furuta University of Colorado Denver
Cormac T. Taylor
Cormac T. Taylor University College Dublin
Charles N. Serhan
Charles N. Serhan Brigham and Women's Hospital
James L. Madara
James L. Madara American Medical Association
Richard S. Blumberg
Richard S. Blumberg Brigham and Women's Hospital
Eric G. Campbell
Eric G. Campbell University of Colorado Denver
Gregory L. Stahl
Gregory L. Stahl Brigham and Women's Hospital
Asma Nusrat
Asma Nusrat University of Michigan–Ann Arbor
Steven P. Balk
Steven P. Balk Beth Israel Deaconess Medical Center

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