World's Best Scientists 2026 revealed!

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Biology and Biochemistry

D-Index
112
Citations
46126
World Ranking
900
National Ranking
563

Medicine

D-Index
113
Citations
46510
World Ranking
4960
National Ranking
2691

Research.com Recognitions

  • 2020 - Fellow of the American Association for the Advancement of Science (AAAS)

Overview

Jerrold R. Turner is affiliated with Brigham and Women's Hospital in the United States. Their research primarily spans the fields of biochemistry, genetics, molecular biology, medicine, and neuroscience, focusing particularly on molecular biology, neurology, surgery, genetics, and immunology.

The main topics of Turner's research include:

  • Barrier Structure and Function Studies
  • Gut microbiota and health
  • Helicobacter pylori-related gastroenterology studies
  • Inflammatory Bowel Disease
  • Neurological Disease Mechanisms and Treatments
  • Microscopic Colitis
  • Connexins and lens biology

The scientist's recent published papers showcase their work on epithelial biology, intestinal permeability, and tight junctions. Notable publications include:

  • "Paracellular permeability and tight junction regulation in gut health and disease," 2023, Nature Reviews Gastroenterology & Hepatology
  • "The Tight Junction Protein ZO-1 Is Dispensable for Barrier Function but Critical for Effective Mucosal Repair," 2021, Gastroenterology
  • "Tight junction proteins occludin and ZO-1 as regulators of epithelial proliferation and survival," 2022, Annals of the New York Academy of Sciences
  • "Tight Junctions as Targets and Effectors of Mucosal Immune Homeostasis," 2020, Cellular and Molecular Gastroenterology and Hepatology
  • "Contributions of Myosin Light Chain Kinase to Regulation of Epithelial Paracellular Permeability and Mucosal Homeostasis," 2020, International Journal of Molecular Sciences

Turner frequently publishes in several scientific journals, with the most common venues including:

  • Gastroenterology
  • bioRxiv (Cold Spring Harbor Laboratory)
  • Inflammatory Bowel Diseases
  • Cellular and Molecular Gastroenterology and Hepatology
  • The FASEB Journal

The scientist has collaborated extensively with several researchers, with the most frequent co-authors being:

  • Wei-Ting Kuo
  • Shabnam Abtahi
  • Sandra D. Chánez-Paredes
  • Nitesh Shashikanth
  • Li Zuo

Among their recognitions, Jerrold R. Turner was named a Fellow of the American Association for the Advancement of Science (AAAS) in 2020.

Best Publications

  • Intestinal mucosal barrier function in health and disease.

    Jerrold R. Turner

  • The intestinal epithelial barrier: a therapeutic target?

    Matthew A. Odenwald;Jerrold R. Turner;Jerrold R. Turner

  • Interferon-γ and Tumor Necrosis Factor-α Synergize to Induce Intestinal Epithelial Barrier Dysfunction by Up-Regulating Myosin Light Chain Kinase Expression

    Fengjun Wang;Fengjun Wang;W. Vallen Graham;Yingmin Wang;Edwina D. Witkowski

  • Molecular basis of epithelial barrier regulation: from basic mechanisms to clinical application.

    Jerrold R. Turner

  • Molecular physiology and pathophysiology of tight junctions. IV. Regulation of tight junctions by extracellular stimuli: nutrients, cytokines, and immune cells.

    A. Nusrat;J. R. Turner;J. L. Madara

  • Physiological regulation of epithelial tight junctions is associated with myosin light-chain phosphorylation.

    Jerrold R. Turner;Jerrold R. Turner;Brian K. Rill;Susan L. Carlson;Denise Carnes

  • Cell Biology of Tight Junction Barrier Regulation and Mucosal Disease

    Aaron Buckley;Jerrold R. Turner

  • A porous defense: the leaky epithelial barrier in intestinal disease.

    Daniel R Clayburgh;Le Shen;Jerrold R Turner

  • Hypoxia-Inducible Factor 1–Dependent Induction of Intestinal Trefoil Factor Protects Barrier Function during Hypoxia

    Glenn T. Furuta;Jerrold R. Turner;Cormac T. Taylor;Robert M. Hershberg

  • Myosin light chain phosphorylation regulates barrier function by remodeling tight junction structure

    Le Shen;Eric D. Black;Edwina D. Witkowski;Wayne I. Lencer

  • Rho protein regulates tight junctions and perijunctional actin organization in polarized epithelia.

    A Nusrat;M Giry;J R Turner;S P Colgan

  • Purification and characterization of a membrane protein (gp45-70) that is a cofactor for cleavage of C3b and C4b.

    Tsukasa Seya;Jerry R. Turner;John P. Atkinson

  • Tight junction proteins claudin-1 and occludin control hepatitis C virus entry and are downregulated during infection to prevent superinfection.

    Shufeng Liu;Wei Yang;Le Shen;Jerrold R. Turner

  • Caveolin-1–dependent occludin endocytosis is required for TNF-induced tight junction regulation in vivo

    Amanda M. Marchiando;Le Shen;W. Vallen Graham;Christopher R. Weber

  • Targeted epithelial tight junction dysfunction causes immune activation and contributes to development of experimental colitis.

    Liping Su;Le Shen;Daniel R. Clayburgh;Sam C. Nalle

  • CD95 promotes tumour growth

    Lina Chen;Lina Chen;Sun Mi Park;Alexei V. Tumanov;Annika Hau;Annika Hau

  • Epithelial myosin light chain kinase–dependent barrier dysfunction mediates T cell activation–induced diarrhea in vivo

    Daniel R. Clayburgh;Terrence A. Barrett;Yueming Tang;Jon B. Meddings

  • A membrane-permeant peptide that inhibits MLC kinase restores barrier function in in vitro models of intestinal disease

    Yevgeny Zolotarevsky;Gail Hecht;Athanasia Koutsouris;Deborah E. Gonzalez

  • Alcohol, Intestinal Bacterial Growth, Intestinal Permeability to Endotoxin, and Medical Consequences: Summary of a Symposium

    Vishnudutt Purohit;J. Christian Bode;Christiane Bode;David A. Brenner

  • Actin Depolymerization Disrupts Tight Junctions via Caveolae-mediated Endocytosis

    Le Shen;Jerrold R. Turner

Frequent Co-Authors

David T. Rubin
David T. Rubin University of Chicago
Yang-Xin Fu
Yang-Xin Fu Tsinghua University
James L. Madara
James L. Madara American Medical Association
John Hart
John Hart University of Illinois at Urbana-Champaign
Eugene B. Chang
Eugene B. Chang University of Chicago
Pradeep K. Dudeja
Pradeep K. Dudeja University of Illinois at Chicago
Mark W. Musch
Mark W. Musch University of Chicago
Stephen B. Hanauer
Stephen B. Hanauer Northwestern University
Clara Abraham
Clara Abraham Yale University
Marshall H. Montrose
Marshall H. Montrose University of Cincinnati

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