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Immunology
China
2026

D-Index & Metrics

Immunology

D-Index
130
Citations
60165
World Ranking
235
National Ranking
2

Medicine

D-Index
130
Citations
60332
World Ranking
2502
National Ranking
17

Research.com Recognitions

  • 2026 - Research.com Immunology in China Leader Award
  • 2025 - Research.com Immunology in China Leader Award

Overview

Yang-Xin Fu is a researcher affiliated with Tsinghua University in China who focuses on medicine, immunology, and microbiology. Their scientific contributions span multiple subfields, primarily immunology and oncology, with significant work also in molecular biology, infectious diseases, and epidemiology.

The main topics of Yang-Xin Fu's research include immunotherapy and immune responses, cancer immunotherapy and biomarkers, CAR-T cell therapy research, immune cell function and interaction, interferon and immune responses, immune cells in cancer, and studies related to SARS-CoV-2 and COVID-19.

They have authored numerous publications in respected venues, frequently publishing in:

  • Nature Communications
  • Cancer Research
  • UNC Libraries
  • The Journal of Experimental Medicine
  • Science Immunology

Yang-Xin Fu has collaborated extensively with coauthors including Hua Peng, Longchao Liu, Zhichen Sun, Chuanhui Han, and Yong Liang.

Representative recent papers authored by Yang-Xin Fu include:

  • "Gut microbial metabolites facilitate anticancer therapy efficacy by modulating cytotoxic CD8+ T cell immunity" (2021, Cell Metabolism)
  • "PD-L1 on dendritic cells attenuates T cell activation and regulates response to immune checkpoint blockade" (2020, Nature Communications)
  • "Intratumoral accumulation of gut microbiota facilitates CD47-based immunotherapy via STING signaling" (2020, The Journal of Experimental Medicine)
  • "Lactate increases stemness of CD8+ T cells to augment anti-tumor immunity" (2022, Nature Communications)
  • "DNA Sensing in Mismatch Repair-Deficient Tumor Cells Is Essential for Anti-tumor Immunity" (2020, Cancer Cell)

Best Publications

  • Innate and adaptive immune cells in the tumor microenvironment

    Thomas F. Gajewski;Hans Schreiber;Yang Xin Fu

  • Irradiation and anti–PD-L1 treatment synergistically promote antitumor immunity in mice

    Liufu Deng;Hua Liang;Byron Burnette;Michael Beckett

  • STING-Dependent Cytosolic DNA Sensing Promotes Radiation-Induced Type I Interferon-Dependent Antitumor Immunity in Immunogenic Tumors

    Liufu Deng;Hua Liang;Meng Xu;Xuanming Yang

  • Therapeutic effects of ablative radiation on local tumor require CD8+ T cells: changing strategies for cancer treatment

    Youjin Lee;Sogyong L. Auh;Yugang Wang;Byron Burnette

  • Radiotherapy and immunotherapy: a beneficial liaison?

    Ralph R. Weichselbaum;Hua Liang;Liufu Deng;Yang Xin Fu

  • The Efficacy of Radiotherapy Relies upon Induction of Type I Interferon–Dependent Innate and Adaptive Immunity

    Byron C. Burnette;Hua Liang;Youjin Lee;Lukasz Chlewicki

  • Commensal bacteria protect against food allergen sensitization

    Andrew T Stefka;Taylor Feehley;Prabhanshu Tripathi;Ju Qiu

  • The aryl hydrocarbon receptor regulates gut immunity through modulation of innate lymphoid cells.

    Ju Qiu;Jennifer J. Heller;Xiaohuan Guo;Zong Ming E. Chen

  • Phagocytosis checkpoints as new targets for cancer immunotherapy.

    Mingye Feng;Wen Jiang;Betty Y.S. Kim;Cheng Cheng Zhang

  • A STING-activating nanovaccine for cancer immunotherapy

    Min Luo;Hua Wang;Zhaohui Wang;Haocheng Cai

  • Development and maturation of secondary lymphoid tissues.

    Yang Xin Fu;David D. Chaplin

  • CD47 blockade triggers T cell–mediated destruction of immunogenic tumors

    Xiaojuan Liu;Yang Pu;Kyle Cron;Liufu Deng

  • The Therapeutic Effect of Anti-HER2/neu Antibody Depends on Both Innate and Adaptive Immunity

    Sae Gwang Park;Zhujun Jiang;Eric D. Mortenson;Liufu Deng

  • Circulating and liver resident CD4+CD25+ regulatory T cells actively influence the antiviral immune response and disease progression in patients with hepatitis B.

    Dongping Xu;Junliang Fu;Lei Jin;Hui Zhang

  • Gut microbial metabolites facilitate anticancer therapy efficacy by modulating cytotoxic CD8+ T cell immunity

    Yao He;Liuhui Fu;Yiping Li;Wenyan Wang

  • Intratumor depletion of CD4+ cells unmasks tumor immunogenicity leading to the rejection of late-stage tumors

    Ping Yu;Youjin Lee;Wenhua Liu;Thomas Krausz

  • Low-dose X-ray radiotherapy–radiodynamic therapy via nanoscale metal–organic frameworks enhances checkpoint blockade immunotherapy

    Kuangda Lu;Chunbai He;Nining Guo;Christina Chan

  • PD-L1 on host cells is essential for PD-L1 blockade–mediated tumor regression

    Haidong Tang;Yong Liang;Robert A. Anders;Janis M. Taube

  • PD-L1 on dendritic cells attenuates T cell activation and regulates response to immune checkpoint blockade

    Qi Peng;Xiangyan Qiu;Zihan Zhang;Silin Zhang

  • Facilitating T Cell Infiltration in Tumor Microenvironment Overcomes Resistance to PD-L1 Blockade

    Haidong Tang;Yang Wang;Yang Wang;Lukasz K. Chlewicki;Yuan Zhang

  • CD95 promotes tumour growth

    Lina Chen;Lina Chen;Sun Mi Park;Alexei V. Tumanov;Annika Hau;Annika Hau

  • Slug is a direct Notch target required for initiation of cardiac cushion cellularization

    Kyle Niessen;YangXin Fu;YangXin Fu;Linda Chang;Pamela A. Hoodless;Pamela A. Hoodless

Frequent Co-Authors

Ralph R. Weichselbaum
Ralph R. Weichselbaum University of Chicago
Jerrold R. Turner
Jerrold R. Turner Brigham and Women's Hospital
Robert A. Anders
Robert A. Anders Johns Hopkins University School of Medicine
Rebecca L. O'Brien
Rebecca L. O'Brien National Jewish Health
Willi K. Born
Willi K. Born University of Colorado Anschutz Medical Campus
Hans Schreiber
Hans Schreiber University of Chicago
David D. Chaplin
David D. Chaplin University of Alabama at Birmingham
Lieping Chen
Lieping Chen Yale University
Hong Tang
Hong Tang Chinese Academy of Sciences
Aly Karsan
Aly Karsan University of British Columbia

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