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Immunology

D-Index
119
Citations
78822
World Ranking
335
National Ranking
210

Medicine

D-Index
119
Citations
78915
World Ranking
3817
National Ranking
2092

Research.com Recognitions

  • Member of the Association of American Physicians
  • Member of the Association of American Physicians
  • Member of the Association of American Physicians
  • Member of the Association of American Physicians

Overview

Thomas F. Gajewski is affiliated with the University of Chicago in the United States. Their research focuses primarily on Medicine, with significant contributions in Immunology and Microbiology. The subfields of study include Oncology, Immunology, Infectious Diseases, Molecular Biology, and Pulmonary and Respiratory Medicine.

Their work revolves around several main topics:

  • Cancer Immunotherapy and Biomarkers
  • CAR-T cell therapy research
  • Immunotherapy and Immune Responses
  • COVID-19 Clinical Research Studies
  • Immune Cell Function and Interaction
  • SARS-CoV-2 and COVID-19 Research
  • Melanoma and MAPK Pathways

Thomas F. Gajewski has published extensively in various scientific venues. The most frequent publication venues include:

  • Regular and Young Investigator Award Abstracts
  • Journal for ImmunoTherapy of Cancer
  • Cancer Research
  • Cancer Immunology Research
  • bioRxiv (Cold Spring Harbor Laboratory)

Some of their recent papers are:

  • "Cancer and the Microbiome-Influence of the Commensal Microbiota on Cancer, Immune Responses, and Immunotherapy" (2020) published in Gastroenterology
  • "Randomized, Double-Blind, Placebo-Controlled, Global Phase III Trial of Talimogene Laherparepvec Combined With Pembrolizumab for Advanced Melanoma" (2022) published in Journal of Clinical Oncology
  • "CXCL9 and CXCL10 bring the heat to tumors" (2022) published in Science Immunology
  • "Pembrolizumab Plus Ipilimumab Following Anti-PD-1/L1 Failure in Melanoma" (2021) published in Journal of Clinical Oncology
  • "Immune cell and tumor cell-derived CXCL10 is indicative of immunotherapy response in metastatic melanoma" (2021) published in Journal for ImmunoTherapy of Cancer

Frequent collaborators include:

  • Emily F. Higgs
  • Sherin J. Rouhani
  • Jonathan Trujillo
  • Yuanyuan Zha
  • Alexandra Cabanov

Thomas F. Gajewski holds membership in the Association of American Physicians. This affiliation represents a recognition within the medical research community.

Best Publications

  • Innate and adaptive immune cells in the tumor microenvironment

    Thomas F. Gajewski;Hans Schreiber;Yang Xin Fu

  • Commensal Bifidobacterium promotes antitumor immunity and facilitates anti–PD-L1 efficacy

    Ayelet Sivan;Leticia Corrales;Nathaniel Hubert;Jason B. Williams

  • The commensal microbiome is associated with anti-PD-1 efficacy in metastatic melanoma patients

    Vyara Matson;Jessica Fessler;Riyue Bao;Tara Chongsuwat

  • Melanoma-intrinsic β-catenin signalling prevents anti-tumour immunity

    Stefani Spranger;Riyue Bao;Thomas F. Gajewski

  • Tumor and Microenvironment Evolution during Immunotherapy with Nivolumab.

    Nadeem Riaz;Jonathan J. Havel;Vladimir Makarov;Alexis Desrichard

  • STING-Dependent Cytosolic DNA Sensing Promotes Radiation-Induced Type I Interferon-Dependent Antitumor Immunity in Immunogenic Tumors

    Liufu Deng;Hua Liang;Meng Xu;Xuanming Yang

  • Up-regulation of PD-L1, IDO, and T(regs) in the melanoma tumor microenvironment is driven by CD8(+) T cells.

    Stefani Spranger;Robbert M. Spaapen;Yuanyuan Zha;Jason Williams

  • STING-Dependent Cytosolic DNA Sensing Mediates Innate Immune Recognition of Immunogenic Tumors

    Seng Ryong Woo;Mercedes Beatriz Fuertes;Leticia Corrales;Stefani Spranger

  • Loss of PTEN Promotes Resistance to T Cell–Mediated Immunotherapy

    Weiyi Peng;Jie Qing Chen;Chengwen Liu;Shruti Malu

  • Direct Activation of STING in the Tumor Microenvironment Leads to Potent and Systemic Tumor Regression and Immunity

    Leticia Corrales;Laura Hix Glickman;Sarah M. McWhirter;David B. Kanne

  • Oncolytic Virotherapy Promotes Intratumoral T Cell Infiltration and Improves Anti-PD-1 Immunotherapy

    Antoni Ribas;Reinhard Dummer;Igor Puzanov;Ari VanderWalde

  • Tumor-Residing Batf3 Dendritic Cells Are Required for Effector T Cell Trafficking and Adoptive T Cell Therapy.

    Stefani Spranger;Daisy Dai;Brendan Horton;Thomas F. Gajewski

  • Host type I IFN signals are required for antitumor CD8+ T cell responses through CD8α+ dendritic cells

    Mercedes B. Fuertes;Aalok K. Kacha;Justin Kline;Seng Ryong Woo

  • Chemokine Expression in Melanoma Metastases Associated with CD8+ T-Cell Recruitment

    Helena Harlin;Yuru Meng;Amy C. Peterson;Yuanyuan Zha

  • Anti-proliferative effect of IFN-gamma in immune regulation. I. IFN-gamma inhibits the proliferation of Th2 but not Th1 murine helper T lymphocyte clones.

    T F Gajewski;F W Fitch

  • Helper T Cell Differentiation Is Controlled by the Cell Cycle

    Jennifer J. Bird;Daniel R. Brown;Alan C. Mullen;Naomi H. Moskowitz

  • Epacadostat plus pembrolizumab versus placebo plus pembrolizumab in patients with unresectable or metastatic melanoma (ECHO-301/KEYNOTE-252): a phase 3, randomised, double-blind study

    Georgina V Long;Reinhard Dummer;Omid Hamid;Thomas F Gajewski

  • PD-L1/B7H-1 Inhibits the Effector Phase of Tumor Rejection by T Cell Receptor (TCR) Transgenic CD8+ T Cells

    Christian Blank;Ian Elliott Brown;Amy C. Peterson;Mike Spiotto

  • Cancer classification using the Immunoscore: a worldwide task force

    Jérôme Galon;Franck Pagès;Francesco M Marincola;Francesco M Marincola;Helen K Angell;Helen K Angell

  • Interaction of PD-L1 on tumor cells with PD-1 on tumor-specific T cells as a mechanism of immune evasion: implications for tumor immunotherapy.

    Christian Blank;Thomas F. Gajewski;Andreas Mackensen

Frequent Co-Authors

Jason J. Luke
Jason J. Luke University of Pittsburgh
F. Stephen Hodi
F. Stephen Hodi Harvard University
Antoni Ribas
Antoni Ribas University of California, Los Angeles
Igor Puzanov
Igor Puzanov Roswell Park Cancer Institute
Frank W. Fitch
Frank W. Fitch University of Chicago
Theodore Karrison
Theodore Karrison University of Chicago
Bernard A. FoxEarle
Bernard A. FoxEarle Earle A. Chiles Research Institute
Pierre Coulie
Pierre Coulie Université Catholique de Louvain
Maria-Luisa Alegre
Maria-Luisa Alegre University of Chicago

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