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Immunology

D-Index
67
Citations
19679
World Ranking
2651
National Ranking
1267

Overview

Bernard A. FoxEarle is affiliated with the Earle A. Chiles Research Institute in the United States. Their research primarily focuses on medicine and immunology and microbiology, contributing extensively to oncology, immunology, molecular biology, infectious diseases, and radiology, nuclear medicine, and imaging.

Their work spans several main topics, including cancer immunotherapy and biomarkers, immunotherapy and immune responses, CAR-T cell therapy research, immune cell function and interaction, vaccines and immunoinformatics approaches, monoclonal and polyclonal antibodies research, and SARS-CoV-2 and COVID-19 research.

Frequent co-authors collaborating with FoxEarle include Shawn M. Jensen, Carlo Bifulco, Rom S. Leidner, Brian Piening, and Carmen Ballesteros-Merino.

The researcher has contributed to multiple publication venues, with many works appearing in Regular and Young Investigator Award Abstracts, Journal of Translational Medicine, Journal for ImmunoTherapy of Cancer, bioRxiv (Cold Spring Harbor Laboratory), and Cancer Research.

Representative recent publications include:

  • Neoantigen T-Cell Receptor Gene Therapy in Pancreatic Cancer, 2022, New England Journal of Medicine
  • Multicenter International Society for Immunotherapy of Cancer Study of the Consensus Immunoscore for the Prediction of Survival and Response to Chemotherapy in Stage III Colon Cancer, 2020, Journal of Clinical Oncology
  • Neoadjuvant anti-OX40 (MEDI6469) therapy in patients with head and neck squamous cell carcinoma activates and expands antigen-specific tumor-infiltrating T cells, 2021, Nature Communications
  • Lymphatic-preserving treatment sequencing with immune checkpoint inhibition unleashes cDC1-dependent antitumor immunity in HNSCC, 2022, Nature Communications
  • Heterodimeric IL-15 delays tumor growth and promotes intratumoral CTL and dendritic cell accumulation by a cytokine network involving XCL1, IFN-γ, CXCL9 and CXCL10, 2020, Journal for ImmunoTherapy of Cancer

In addition to journal articles, FoxEarle has published a book titled Cyber Mission Thread Analysis: An Implementation Guide for Process Planning and Execution, released in 2022 through RAND Corporation eBooks.

Best Publications

  • International validation of the consensus Immunoscore for the classification of colon cancer: a prognostic and accuracy study

    Franck Pagès;Bernhard Mlecnik;Florence Marliot;Gabriela Bindea;Gabriela Bindea;Gabriela Bindea

  • Towards the introduction of the 'Immunoscore' in the classification of malignant tumours.

    Jérôme Galon;Jérôme Galon;Jérôme Galon;Bernhard Mlecnik;Bernhard Mlecnik;Bernhard Mlecnik;Gabriela Bindea;Gabriela Bindea;Gabriela Bindea;Helen K. Angell;Helen K. Angell;Helen K. Angell

  • Direct gene transfer with DNA-liposome complexes in melanoma: expression, biologic activity, and lack of toxicity in humans

    Gary J. Nabel;Elizabeth G. Nabel;Zhi Yong Yang;Bernard A. Fox

  • Cancer classification using the Immunoscore: a worldwide task force

    Jérôme Galon;Franck Pagès;Francesco M Marincola;Francesco M Marincola;Helen K Angell;Helen K Angell

  • Co-expression of CD39 and CD103 identifies tumor-reactive CD8 T cells in human solid tumors

    Thomas Duhen;Rebekka Duhen;Ryan Montler;Jake Moses

  • The immune score as a new possible approach for the classification of cancer

    Jérôme Galon;Franck Pagès;Francesco M Marincola;Francesco M Marincola;Magdalena Thurin

  • OX40 is a potent immune-stimulating target in late-stage cancer patients.

    Brendan D. Curti;Magdalena Kovacsovics-Bankowski;Nicholas Morris;Edwin Walker

  • Cancer and inflammation: Promise for biologic therapy

    Sandra Demaria;Eli Pikarsky;Michael Karin;Lisa M. Coussens

  • Optimizing Timing of Immunotherapy Improves Control of Tumors by Hypofractionated Radiation Therapy.

    Kristina H. Young;Jason R. Baird;Talicia Savage;Benjamin Cottam

  • Granulocyte–Macrophage Colony-Stimulating Factor Gene-Modified Autologous Tumor Vaccines in Non–Small-Cell Lung Cancer

    John Nemunaitis;Daniel Sterman;David Jablons;John W. Smith

  • Timing of PD-1 Blockade Is Critical to Effective Combination Immunotherapy with Anti-OX40.

    David J. Messenheimer;Shawn M. Jensen;Michael E. Afentoulis;Keith W. Wegmann

  • Novel technologies and emerging biomarkers for personalized cancer immunotherapy.

    Jianda Yuan;Priti S. Hegde;Raphael Clynes;Periklis G. Foukas;Periklis G. Foukas

  • Phase 1/2 trial of autologous tumor mixed with an allogeneic GVAX ® vaccine in advanced-stage non-small-cell lung cancer

    J Nemunaitis;T Jahan;H Ross;D Sterman

  • Future perspectives in melanoma research

    Paolo A. Ascierto;Sanjiv Agarwala;Gerardo Botti;Alessandra Cesano

  • Adoptive immunotherapy with vaccine-primed lymph node cells secondarily activated with anti-CD3 and interleukin-2.

    A E Chang;A Aruga;M J Cameron;V K Sondak

  • Multicenter International Society for Immunotherapy of Cancer Study of the Consensus Immunoscore for the Prediction of Survival and Response to Chemotherapy in Stage III Colon Cancer.

    Bernhard Mlecnik;Carlo Bifulco;Gabriela Bindea;Gabriela Bindea;Florence Marliot

  • Defining the critical hurdles in cancer immunotherapy

    Bernard A. Fox;Bernard A. Fox;Dolores J. Schendel;Lisa H. Butterfield;Steinar Aamdal

  • Immunotherapy of Malignancy by In Vivo Gene Transfer into Tumors

    Gary J. Nabel;Alfred Chang;Elizabeth G. Nabel;Gregory Plautz

  • Multiparametric immune profiling in HPV- oral squamous cell cancer.

    Zipei Feng;Daniel Bethmann;Matthias Kappler;Carmen Ballesteros-Merino

  • Gene-Modified Tumor Vaccine with Therapeutic Potential Shifts Tumor-Specific T Cell Response from a Type 2 to a Type 1 Cytokine Profile

    Hong-Ming Hu;Walter J. Urba;Bernard A. Fox

  • Immunoscore and Immunoprofiling in cancer: an update from the melanoma and immunotherapy bridge 2015.

    J Galon;J Galon;B A Fox;B A Fox;C B Bifulco;G Masucci

Frequent Co-Authors

Walter J. Urba
Walter J. Urba Providence Portland Medical Center
Paolo A. Ascierto
Paolo A. Ascierto National Institutes of Health
Francesco M. Marincola
Francesco M. Marincola National Institutes of Health
Thomas F. Gajewski
Thomas F. Gajewski University of Chicago
Lisa H. Butterfield
Lisa H. Butterfield University of California, San Francisco
Yutaka Kawakami
Yutaka Kawakami International University Of Health And Welfare Atami Hospital
Toshihiko Torigoe
Toshihiko Torigoe Sapporo Medical University
Iris D. Nagtegaal
Iris D. Nagtegaal Radboud University
Pamela S. Ohashi
Pamela S. Ohashi Princess Margaret Cancer Centre

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